Page last updated: 2024-10-22

ambroxol and Infections, Paramyxoviridae

ambroxol has been researched along with Infections, Paramyxoviridae in 1 studies

Ambroxol: A metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually administered as the hydrochloride.

Research Excerpts

ExcerptRelevanceReference
"It was investigated whether the botanical drug combination Sinupret is able to modulate the resistance of mice to a respiratory tract infection with Sendai virus (Parainfluenza viridae) if given prophylactically to the animals."1.31Enhanced resistance to Sendai virus infection in DBA/2J mice with a botanical drug combination (Sinupret). ( März, RW; Ottendorfer, D; Schmolz, M; Sieder, C, 2001)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schmolz, M1
Ottendorfer, D1
März, RW1
Sieder, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Herbal Formula (SBL) for the Treatment of Perennial Allergic Rhinitis: A Randomized, Double-blind, Placebo-controlled Clinical Trial[NCT00456755]Phase 2126 participants (Actual)Interventional2004-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Allergic Rhinitis Symptom Score Including Rhinorrhea, Nasal Obstruction, Sneezing, Itchy Nose and Itchy Eyes at Week 4

The severity of PAR was evaluated by means of a daily symptom diary chart. Patients were instructed to grade retrospectively everyday before bedtime, their generalwell-being, nasalsymptoms (nasal blockage, rhinorrhea, nose itching, sneezing) and non-nasal symptoms(itching eyes, tearing eyes, redness of eyes, itching of ears or palate) on the diary chart. A 4-point severity scale from no symptoms (0), mild (1), moderated (2) to severe (3) was used. (NCT00456755)
Timeframe: 4 week

,
InterventionUnit Score (Mean)
General HealthNose BlockageRhinorrhea volumeSneeze FrequencyNose ItchingEyes ItchingTearsEye CongestionEar itching
Placebo2.81.211.241.180.990.560.430.260.61
Shi-Bi-Lin2.821.191.261.151.110.730.520.370.81

Quality of Life (Difference Between Baseline and Week 4)

SF-36 QOL questionnaire administrated before and after treatment. It has eight domains: general health (GH), physical functioning (PF), social functioning (SF), role limitation caused by physical problems (RP), bodily pain (BP), role limitations caused by emotional problem (RE), mental health (MH), and vitality (VT). Each domain was started from 0 (worst health) to 100 (best health). (NCT00456755)
Timeframe: 4 week

,
InterventionUnit Score (Mean)
Physical functioningRole limitation by physical problemBodily painGeneral HealthVitalitySocail functioningRole limitation by emotional problemMental health
Placebo03-10-9131731
Shi-Bi-Lin47-3-7817131

Other Studies

1 other study available for ambroxol and Infections, Paramyxoviridae

ArticleYear
Enhanced resistance to Sendai virus infection in DBA/2J mice with a botanical drug combination (Sinupret).
    International immunopharmacology, 2001, Volume: 1, Issue:9-10

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adjuvants, Immunologic; Ambroxol; Animals; CD4-CD8 Ratio; Expecto

2001