ambroxol has been researched along with Infantile Respiratory Distress Syndrome in 45 studies
Ambroxol: A metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually administered as the hydrochloride.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the efficacy and safety of giving ambroxol to pregnant women who are at risk of preterm birth, for preventing neonatal RDS." | 8.90 | Ambroxol for women at risk of preterm birth for preventing neonatal respiratory distress syndrome. ( Gonzalez Garay, AG; Reveiz, L; Solis Galicia, C; Velasco Hidalgo, L, 2014) |
| "To evaluate the efficacy and safety of giving ambroxol to pregnant women who are at risk of preterm birth, for preventing neonatal RDS." | 4.90 | Ambroxol for women at risk of preterm birth for preventing neonatal respiratory distress syndrome. ( Gonzalez Garay, AG; Reveiz, L; Solis Galicia, C; Velasco Hidalgo, L, 2014) |
| "Ambroxol did not cause any significant maternal or infant side effects." | 3.78 | Antenatal ambroxol usage in the prevention of infant respiratory distress syndrome. Beneficial and adverse effects. ( Kimya, Y; Küçükkömürcü, S; Ozan, H; Uncu, G, 1995) |
| "Ambroxol treatment group consisted of 39 subjects in whom 1,000 mg of ambroxol diluted in 500 ml of 5% glucose solution was given intravenously for 4 hours once a day for 3 days, while the control group consisted of 41 subjects in whom ambroxol was not administered." | 2.69 | Antenatal use of ambroxol for the prevention of infant respiratory distress syndrome. ( Fernandez, AM; Laoag-Fernandez, JB; Maruo, T, 2000) |
| "Ambroxol was significantly more effective than betamethasone in twin births, in infants born before the 31st week, when ROM to delivery time was more than 48 hours, when treatment to delivery time was between 2 and 7 days and in female infants." | 2.66 | An alternative to steroids for prevention of respiratory distress syndrome (RDS): multicenter controlled study to compare ambroxol and betamethasone. ( Corbella, E; Lazzarin, A; Luerti, M; Zavattini, G, 1987) |
| "Ambroxol was administered for a maximum of 5 days - 1000 mg in an infusion solution; betamethasone was injected intramuscularly in 2 daily doses of 8 mg." | 2.66 | [Induction of fetal lung maturation using ambroxol and betamethasone. Results of an open multicenter study]. ( Ponnath, H; Wiest, W; Wolff, F, 1987) |
| "The ambroxol-treated group had lower risk of neonatal infection than the corticosteroid-treated group (RR = 0." | 2.49 | Prevention of respiratory distress syndrome in preterm infants by antenatal ambroxol: a meta-analysis of randomized controlled trials. ( Huang, XM; Lu, H; Wu, QQ; Zhang, ZQ, 2013) |
| "Ambroxol has been shown to significantly reduce RDS compared to placebo without causing important adverse effects in either mother or baby." | 2.38 | Prevention and treatment of fetal lung immaturity. ( Cosmi, EV; Di Renzo, GC, 1989) |
| "Bronchopulmonary dysplasia was diagnosed in 25% of the infants in the control group, compared to none diagnosed in the work group." | 1.37 | [Antenatal ambroxol administration for prevention of respiratopry distress syndrome in preterm infants: preliminary report]. ( Andreeva, A; Hitrova, S; Jekova, N; Marinov, B, 2011) |
| "Carnitine is a body-owned Betaine which is wide-spread in living nature in the form of a physiologic metabolit." | 1.26 | [Pharmacologic influencing of fetal phospholipide synthesis. Part II: Carnitin - a new way of dyspnea syndrome prophylaxis? (author's transl)]. ( Blümel, G; Erhardt, W; Krieglsteiner, P; Lohninger, A; Riedl, W, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (46.67) | 18.7374 |
| 1990's | 12 (26.67) | 18.2507 |
| 2000's | 5 (11.11) | 29.6817 |
| 2010's | 6 (13.33) | 24.3611 |
| 2020's | 1 (2.22) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, JS | 1 |
| Li, BH | 1 |
| Xu, YQ | 1 |
| Li, J | 1 |
| Lin, Y | 1 |
| Zhang, H | 1 |
| Liu, J | 1 |
| Liu, T | 1 |
| Wang, Y | 1 |
| Dai, W | 1 |
| Gonzalez Garay, AG | 1 |
| Reveiz, L | 1 |
| Velasco Hidalgo, L | 1 |
| Solis Galicia, C | 1 |
| Justus, G | 1 |
| Sloboda, DM | 1 |
| Henrich, W | 1 |
| Plagemann, A | 1 |
| Dudenhausen, JW | 2 |
| Braun, T | 1 |
| Fan, YZ | 1 |
| Wen, ZL | 1 |
| Zhang, ZQ | 2 |
| Huang, XM | 2 |
| Lu, H | 2 |
| Marinov, B | 1 |
| Jekova, N | 1 |
| Andreeva, A | 1 |
| Hitrova, S | 1 |
| Wu, QQ | 1 |
| Hu, Q | 1 |
| Lian, JM | 1 |
| Li, JQ | 1 |
| Akkoca Yildiz, O | 1 |
| Henahan, J | 1 |
| Lazzarin, A | 3 |
| Luerti, M | 4 |
| Uberti-Foppa, C | 2 |
| Zavattini, G | 4 |
| Rossi, A | 1 |
| Tornaghi, R | 1 |
| Spagnolo, D | 1 |
| Bianchi, C | 1 |
| Barbera, AG | 1 |
| Corbella, E | 3 |
| Snell, NJ | 1 |
| Kimya, Y | 1 |
| Küçükkömürcü, S | 1 |
| Ozan, H | 1 |
| Uncu, G | 1 |
| Lenclen, R | 1 |
| Paupe, A | 1 |
| Philippe, HJ | 1 |
| Olivier-Martin, M | 1 |
| Nisand, I | 1 |
| Sackey, S | 1 |
| Gadzinowski, J | 1 |
| Szymankiewicz, M | 1 |
| Breborowicz, GH | 1 |
| Rudnicki, J | 1 |
| Patalan, J | 1 |
| Rózewicki, K | 1 |
| Dani, C | 1 |
| Grella, PV | 1 |
| Lazzarin, L | 1 |
| Rubaltelli, FF | 1 |
| Schmalisch, G | 2 |
| Wauer, RR | 2 |
| Böhme, B | 2 |
| Laoag-Fernandez, JB | 1 |
| Fernandez, AM | 1 |
| Maruo, T | 1 |
| Mĕchurová, A | 1 |
| Renovanz, HD | 1 |
| von Seefeld, H | 1 |
| Endell, W | 1 |
| Grosspietzsch, R | 1 |
| Klink, F | 1 |
| von Klitzing, L | 1 |
| Oberheuser, F | 1 |
| Lohninger, A | 1 |
| Krieglsteiner, P | 1 |
| Riedl, W | 1 |
| Erhardt, W | 1 |
| Blümel, G | 1 |
| Geibel, W | 1 |
| Rindt, W | 1 |
| Becker, H | 1 |
| Durisová, A | 1 |
| Arand, J | 1 |
| Lehmann, D | 1 |
| Winsel, K | 1 |
| Carrera, G | 1 |
| Liberatore, A | 1 |
| Riboni, G | 1 |
| Clementi, M | 1 |
| Grio, R | 1 |
| Marchino, GL | 1 |
| Giobbe, C | 1 |
| Zaccheo, F | 1 |
| Ferrara, L | 1 |
| Castello, C | 1 |
| Ardissone, D | 1 |
| Mazza, O | 1 |
| Piacentino, R | 1 |
| Gerner, R | 1 |
| Heytmanek, G | 1 |
| Salzer, H | 2 |
| Vityska-Binstorfer, E | 1 |
| Genger, H | 1 |
| Metka, M | 1 |
| Pfersmann, R | 1 |
| Wolff, F | 2 |
| Weidinger, H | 1 |
| Cosmi, EV | 2 |
| Di Renzo, GC | 2 |
| Anceschi, MM | 1 |
| Guidetti, R | 1 |
| Knitza, R | 1 |
| Linke, M | 1 |
| Wisser, J | 1 |
| Hepp, H | 1 |
| Colombo, ML | 1 |
| Dogliani, P | 1 |
| Ulla, L | 1 |
| Marini, A | 1 |
| Franzetti, M | 1 |
| Gios, G | 1 |
| Flauto, U | 1 |
| Arosio, A | 1 |
| Maccabruni, M | 1 |
| Rondini, G | 1 |
| Chirico, G | 1 |
| Giancola, A | 1 |
| Console, V | 1 |
| Disse, BG | 1 |
| Vytiska-Binstorfer, E | 1 |
| Simbruner, G | 1 |
| Papageorgiou, A | 1 |
| Stern, L | 1 |
| Ponnath, H | 1 |
| Wiest, W | 1 |
| Bajorek, J | 1 |
| Czeszyńska, M | 1 |
| Gizejowska, M | 1 |
| Baryła-Pankiewicz, E | 1 |
| Capsoni, F | 1 |
| Galli, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Ambroxol as a Novel Disease Modifying Treatment for Parkinson's Disease Dementia[NCT02914366] | Phase 2 | 55 participants (Actual) | Interventional | 2015-11-30 | Active, not recruiting | ||
| Ambroxol as a Novel Disease Modifying Treatment for Lewy Body Dementia[NCT04405596] | Phase 1/Phase 2 | 15 participants (Anticipated) | Interventional | 2025-01-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
15 reviews available for ambroxol and Infantile Respiratory Distress Syndrome
| Article | Year |
|---|---|
Antenatal maternal medication administration in preventing respiratory distress syndrome of premature infants: A network meta-analysis.
Topics: Ambroxol; Betamethasone; Bronchopulmonary Dysplasia; Dexamethasone; Female; Humans; Infant, Newborn; | 2018 |
Ambroxol for women at risk of preterm birth for preventing neonatal respiratory distress syndrome.
Topics: Adrenal Cortex Hormones; Ambroxol; Betamethasone; Expectorants; Female; Humans; Infant, Newborn; Pre | 2014 |
Avoiding the prenatal programming effects of glucocorticoids: are there alternative treatments for the induction of antenatal lung maturation?
Topics: Ambroxol; Animals; Female; Fetal Organ Maturity; Glucocorticoids; Growth Substances; Humans; Infant, | 2015 |
[Ambroxol for the prevention of respiratory distress syndrome in preterm infants: a meta analysis].
Topics: Ambroxol; Bronchopulmonary Dysplasia; Cerebral Hemorrhage; Ductus Arteriosus, Patent; Humans; Infant | 2010 |
Prevention of respiratory distress syndrome in preterm infants by antenatal ambroxol: a meta-analysis of randomized controlled trials.
Topics: Ambroxol; Confidence Intervals; Expectorants; Humans; Infant, Newborn; Infant, Premature; Odds Ratio | 2013 |
[Ambroxol].
Topics: Ambroxol; Anti-Inflammatory Agents; Antioxidants; Asthma; Bronchial Hyperreactivity; Cystic Fibrosis | 2006 |
Antenatal ambroxol usage in the prevention of infant respiratory distress syndrome. Beneficial and adverse effects.
Topics: Ambroxol; Expectorants; Female; Fetal Organ Maturity; Gestational Age; Humans; Infant, Newborn; Lung | 1995 |
[Prenatal prevention of infant respiratory distress syndrome. 2nd part: clinical applications and indications].
Topics: Adrenal Cortex Hormones; Ambroxol; Drug Therapy, Combination; Female; Humans; Infant, Newborn; Pregn | 1995 |
[Problems in inducing pulmonary maturation in relation to premature delivery].
Topics: Ambroxol; Female; Fetal Organ Maturity; Glucocorticoids; Humans; Infant, Newborn; Lung; Obstetric La | 2000 |
[The antioxidative and inflammation inhibiting properties of ambroxol].
Topics: Ambroxol; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; | 1992 |
[Respiratory distress syndrome in premature births].
Topics: Ambroxol; Cesarean Section; Humans; Infant, Newborn; Infant, Premature, Diseases; Respiratory Distre | 1990 |
[Prevention of pediatric respiratory distress syndrome with special reference to glucocorticoids].
Topics: Ambroxol; Female; Fetal Organ Maturity; Glucocorticoids; Humans; Infant, Newborn; Lung; Pregnancy; R | 1990 |
Prevention and treatment of fetal lung immaturity.
Topics: Adrenergic beta-Agonists; Ambroxol; Aminophylline; Female; Fetal Organ Maturity; Glucocorticoids; Hu | 1989 |
The pharmacology of ambroxol--review and new results.
Topics: Airway Resistance; Ambroxol; Animals; Bromhexine; Bronchitis; Chronic Disease; Humans; Infant, Newbo | 1987 |
Antenatal prevention of the neonatal respiratory distress syndrome: benefits and potential risks for the mother and the infant.
Topics: Ambroxol; Aminophylline; Female; Fetal Organ Maturity; Follow-Up Studies; Gestational Age; Glucocort | 1986 |
15 trials available for ambroxol and Infantile Respiratory Distress Syndrome
| Article | Year |
|---|---|
Therapeutic effect of micropump intravenous infusion of ambroxol hydrochloride on respiratory distress syndrome in premature infants.
Topics: Ambroxol; Child; Female; Humans; Infant; Infant, Newborn; Infant, Premature; Infusions, Intravenous; | 2023 |
[Efficacy of intravenous or atomizing ambroxol for prevention of respiratory distress syndrome in preterm infants].
Topics: Administration, Inhalation; Ambroxol; Female; Humans; Infant, Newborn; Infant, Premature; Injections | 2006 |
Expectorant promising for treating infant respiratory distress syndrome.
Topics: Ambroxol; Betamethasone; Clinical Trials as Topic; Female; Fetus; Humans; Infant, Newborn; Maternal- | 1983 |
Antenatal ambroxol usage in the prevention of infant respiratory distress syndrome. Beneficial and adverse effects.
Topics: Ambroxol; Expectorants; Female; Fetal Organ Maturity; Gestational Age; Humans; Infant, Newborn; Lung | 1995 |
Antenatal ambroxol treatment does not prevent the respiratory distress syndrome in premature infants.
Topics: Ambroxol; Chi-Square Distribution; Confidence Intervals; Expectorants; Humans; Infant, Newborn; Infa | 1997 |
Changes in pulmonary function in preterm infants recovering from RDS following early treatment with ambroxol: results of a randomized trial.
Topics: Ambroxol; Expectorants; Female; Humans; Infant, Newborn; Infant, Premature; Male; Respiration; Respi | 1999 |
Changes in pulmonary function in preterm infants recovering from RDS following early treatment with ambroxol: results of a randomized trial.
Topics: Ambroxol; Expectorants; Female; Humans; Infant, Newborn; Infant, Premature; Male; Respiration; Respi | 1999 |
Changes in pulmonary function in preterm infants recovering from RDS following early treatment with ambroxol: results of a randomized trial.
Topics: Ambroxol; Expectorants; Female; Humans; Infant, Newborn; Infant, Premature; Male; Respiration; Respi | 1999 |
Changes in pulmonary function in preterm infants recovering from RDS following early treatment with ambroxol: results of a randomized trial.
Topics: Ambroxol; Expectorants; Female; Humans; Infant, Newborn; Infant, Premature; Male; Respiration; Respi | 1999 |
Antenatal use of ambroxol for the prevention of infant respiratory distress syndrome.
Topics: Adult; Ambroxol; Apgar Score; Drug Administration Schedule; Expectorants; Female; Fetal Membranes, P | 2000 |
Antenatal use of ambroxol for the prevention of infant respiratory distress syndrome.
Topics: Adult; Ambroxol; Apgar Score; Drug Administration Schedule; Expectorants; Female; Fetal Membranes, P | 2000 |
Antenatal use of ambroxol for the prevention of infant respiratory distress syndrome.
Topics: Adult; Ambroxol; Apgar Score; Drug Administration Schedule; Expectorants; Female; Fetal Membranes, P | 2000 |
Antenatal use of ambroxol for the prevention of infant respiratory distress syndrome.
Topics: Adult; Ambroxol; Apgar Score; Drug Administration Schedule; Expectorants; Female; Fetal Membranes, P | 2000 |
Randomized double blind trial of Ambroxol for the treatment of respiratory distress syndrome.
Topics: Ambroxol; Double-Blind Method; Humans; Infant, Low Birth Weight; Infant, Newborn; Male; Respiratory | 1992 |
[Surfactant and ambroxol in the therapy of idiopathic respiratory syndrome in newborn infants].
Topics: Ambroxol; Humans; Infant, Newborn; Infusions, Intravenous; Positive-Pressure Respiration; Pulmonary | 1991 |
[Ambroxol versus betamethasone for the promotion of antepartum lung maturity in pathological pregnancies].
Topics: Ambroxol; Betamethasone; Bromhexine; Double-Blind Method; Female; Fetal Organ Maturity; Gestational | 1990 |
Requirements of perinatal prevention and treatment of respiratory distress syndrome.
Topics: Ambroxol; Aminophylline; Asphyxia Neonatorum; Clinical Trials as Topic; Double-Blind Method; Female; | 1989 |
Ambroxol in the treatment of idiopathic respiratory distress syndrome. An interim report on a controlled double-blind multicenter study versus placebo.
Topics: Ambroxol; Blood Gas Analysis; Bromhexine; Clinical Trials as Topic; Double-Blind Method; Humans; Inf | 1987 |
An alternative to steroids for prevention of respiratory distress syndrome (RDS): multicenter controlled study to compare ambroxol and betamethasone.
Topics: Ambroxol; Betamethasone; Bromhexine; Clinical Trials as Topic; Female; Humans; Infant, Newborn; Male | 1987 |
An alternative to steroids for prevention of respiratory distress syndrome (RDS): multicenter controlled study to compare ambroxol and betamethasone.
Topics: Ambroxol; Betamethasone; Bromhexine; Clinical Trials as Topic; Female; Humans; Infant, Newborn; Male | 1987 |
An alternative to steroids for prevention of respiratory distress syndrome (RDS): multicenter controlled study to compare ambroxol and betamethasone.
Topics: Ambroxol; Betamethasone; Bromhexine; Clinical Trials as Topic; Female; Humans; Infant, Newborn; Male | 1987 |
An alternative to steroids for prevention of respiratory distress syndrome (RDS): multicenter controlled study to compare ambroxol and betamethasone.
Topics: Ambroxol; Betamethasone; Bromhexine; Clinical Trials as Topic; Female; Humans; Infant, Newborn; Male | 1987 |
[Ambroxol in comparison with betamethasone for the stimulation of antepartal lung maturity. A clinical double-blind study].
Topics: Ambroxol; Betamethasone; Bromhexine; Clinical Trials as Topic; Double-Blind Method; Female; Fetal Or | 1986 |
[Induction of fetal lung maturation using ambroxol and betamethasone. Results of an open multicenter study].
Topics: Ambroxol; Betamethasone; Bromhexine; Clinical Trials as Topic; Double-Blind Method; Female; Fetal Or | 1987 |
16 other studies available for ambroxol and Infantile Respiratory Distress Syndrome
| Article | Year |
|---|---|
[Efficacy of different dosages of ambroxol hydrochloride in the prevention of neonatal respiratory distress syndrome].
Topics: Ambroxol; Dose-Response Relationship, Drug; Female; Humans; Incidence; Infant, Newborn; Male; Respir | 2009 |
[Antenatal ambroxol administration for prevention of respiratopry distress syndrome in preterm infants: preliminary report].
Topics: Adult; Ambroxol; Bronchopulmonary Dysplasia; Expectorants; Female; Humans; Infant, Newborn; Pregnanc | 2011 |
Polymorphonuclear leucocytes functions from premature infants after prevention of respiratory distress syndrome with betamethasone and ambroxol.
Topics: Ambroxol; Betamethasone; Bromhexine; Female; Gestational Age; Humans; Infant, Newborn; Infant, Prema | 1984 |
Cord blood prolactin and thyroid hormone levels after antenatal administration of betamethasone or ambroxol for prevention of respiratory distress syndrome (RDS).
Topics: Ambroxol; Betamethasone; Bromhexine; Female; Fetal Blood; Gestational Age; Humans; Infant, Newborn; | 1984 |
Advances in respiratory distress syndrome.
Topics: Ambroxol; Bromhexine; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Pregnancy; Respirato | 1982 |
[Evaluation of ambroxol given prenatally and postnatally on gas exchange in the newborn with respiratory distress syndrome].
Topics: Ambroxol; Drug Administration Schedule; Expectorants; Humans; Infant, Newborn; Lung; Postnatal Care; | 1995 |
[Surfactant and respiratory distress syndrome].
Topics: Adrenergic beta-Agonists; Ambroxol; Amniotic Fluid; Animals; Dexamethasone; Glucocorticoids; Humans; | 1978 |
[Prevention and therapy of respiratory distress syndrome in premature infants by means of bromhexine metabolite VIII. Animal experimental studies on the therapeutic efficacy of bromhexine metabolite VIII in premature respiratory distress syndrome].
Topics: Ambroxol; Amniotic Fluid; Animals; Bile; Bromhexine; Female; Fetal Blood; Humans; Infant, Newborn; K | 1977 |
[Pharmacologic influencing of fetal phospholipide synthesis. Part II: Carnitin - a new way of dyspnea syndrome prophylaxis? (author's transl)].
Topics: Ambroxol; Animals; Betamethasone; Carnitine; Female; Fetus; Humans; Infant, Newborn; Phospholipids; | 1978 |
[RDS prevention by prednilyden and ambroxol. A comparative study].
Topics: Ambroxol; Bromhexine; Female; Glucocorticoids; Humans; Infant, Newborn; Pregnancy; Respiratory Distr | 1979 |
[Ambroxol in the treatment of idiopathic respiratory distress syndrome].
Topics: Ambroxol; Humans; Infant, Newborn; Respiratory Distress Syndrome, Newborn | 1992 |
[The status of drug prevention of respiratory distress syndrome in German gynecologic clinics].
Topics: Ambroxol; Betamethasone; Dexamethasone; Female; Fetal Organ Maturity; Follow-Up Studies; Gestational | 1989 |
[Use of ambroxol in the therapy of neonatal respiratory insufficiency].
Topics: Ambroxol; Bromhexine; Drug Evaluation; Humans; Infant, Newborn; Pneumonia, Aspiration; Pulmonary Ate | 1988 |
Alternatives to the antenatal glucocorticoid treatment for the prevention of respiratory distress syndrome.
Topics: Ambroxol; Aminophylline; Animals; Carnitine; Embryonic and Fetal Development; Fat Emulsions, Intrave | 1987 |
[Effect of Lasolvan on the course of respiratory distress syndrome in newborn infants].
Topics: Ambroxol; Bromhexine; Female; Humans; Infant, Newborn; Male; Respiratory Distress Syndrome, Newborn | 1987 |
A study of cellular immunity in newborns after prevention of respiratory distress syndrome (RDS).
Topics: Ambroxol; Betamethasone; Bromhexine; Chemotaxis, Leukocyte; Female; Humans; Immunity, Cellular; Infa | 1986 |