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ambroxol and Disease, Pulmonary

ambroxol has been researched along with Disease, Pulmonary in 32 studies

Ambroxol: A metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually administered as the hydrochloride.

Research Excerpts

ExcerptRelevanceReference
"This paper was aimed at investigating the effects of bronchoalveolar lavage (BAL) with ambroxol hydrochloride (AH) on treating pulmonary infection and on serum proinflammatory cytokines and oxidative stress responses in patients with cerebral infarction (CI)."7.96Effects of Bronchoalveolar Lavage with Ambroxol Hydrochloride on Treating Pulmonary Infection in Patients with Cerebral Infarction and on Serum Proinflammatory Cytokines, MDA and SOD. ( Cheng, J; Meng, F; Sang, P; Wang, J, 2020)
"Although whole lung lavage is the first-line therapy for pulmonary alveolar proteinosis, oral ambroxol could be an alternative treatment option, even in patients with severe respiratory compromise."7.81Marked improvement in autoimmune pulmonary alveolar proteinosis with severe hypoxemia in a patient treated with ambroxol: a case report. ( Matsumoto, Y; Matsuoka, H; Oda, N; Okada, N; Suzuki, Y; Tamai, K; Yoshimatsu, H, 2015)
"This paper was aimed at investigating the effects of bronchoalveolar lavage (BAL) with ambroxol hydrochloride (AH) on treating pulmonary infection and on serum proinflammatory cytokines and oxidative stress responses in patients with cerebral infarction (CI)."3.96Effects of Bronchoalveolar Lavage with Ambroxol Hydrochloride on Treating Pulmonary Infection in Patients with Cerebral Infarction and on Serum Proinflammatory Cytokines, MDA and SOD. ( Cheng, J; Meng, F; Sang, P; Wang, J, 2020)
"Although whole lung lavage is the first-line therapy for pulmonary alveolar proteinosis, oral ambroxol could be an alternative treatment option, even in patients with severe respiratory compromise."3.81Marked improvement in autoimmune pulmonary alveolar proteinosis with severe hypoxemia in a patient treated with ambroxol: a case report. ( Matsumoto, Y; Matsuoka, H; Oda, N; Okada, N; Suzuki, Y; Tamai, K; Yoshimatsu, H, 2015)
" With regard to a possible therapeutic application in this context the effect of bromhexine and ambroxol on the activity of AM of of guinea-pigs and of patients with lung diseases was investigated."3.67[Modulation of alveolar macrophage activity by ambroxol, bromhexine and exogenous arachidonic acid]. ( Eckert, H; Grollmuss, H; Unger, U; Winsel, K, 1985)
"Ambroxol, a drug capable of elevating the phospholipid content in healthy rabbit lungs, was tested on two models of experimental lung injury, lung changes in sepsis induced by a peritonitis and in bromcarbamide intoxication."3.67Ambroxol increases the choline but not fatty acid incorporation into lung phospholipids in experimental lung disorders. ( Müller, B; von Wichert, P; Wilke, A, 1987)
"The clinical activity of trans-4-[(2-amino-3,5-dibromo-benzyl)-amino]-cyclohexanol-hydrochloride (ambroxol, NA 872) as well as its influence on lung function was examined in a total of 63 patients (34 suffering from silicosis, 28 from chronic obstructive bronchitis and 1 from cryptococcosis)."3.66[Therapeutic study on ambroxol in chronic bronchopulmonary diseases (author's transl)]. ( Curti, PC; Renovanz, HD, 1978)
"Fifty younger patients without known pulmonary disease were randomly assigned into 2 groups."2.73Protective effect of ambroxol on pulmonary function after cardiopulmonary bypass. ( Cagli, K; Ergun, K; Gedik, S; Hizarci, M; Kocabeyoglu, SS; Korkmaz, K; Kunt, A; Lafci, G; Ulas, MM, 2008)
"Cystic fibrosis is an inherited condition resulting in thickened, sticky respiratory secretions."2.49Nebulized and oral thiol derivatives for pulmonary disease in cystic fibrosis. ( Nash, EF; Ratjen, F; Stephenson, A; Tam, J; Tullis, E, 2013)
"Cystic fibrosis is an inherited condition resulting in thickened, sticky respiratory secretions."2.45Nebulized and oral thiol derivatives for pulmonary disease in cystic fibrosis. ( Nash, EF; Ratjen, F; Stephenson, A; Tullis, E, 2009)
"This is most evident in pulmonary diseases characterized by low glutathione levels and high oxidant production by inflammatory cells (e."2.40Characterization of N-acetylcysteine and ambroxol in anti-oxidant therapy. ( Gillissen, A; Nowak, D, 1998)
"Ambroxol has been established for decades in the treatment of acute and chronic respiratory diseases."1.46[More than expectorant: new scientific data on ambroxol in the context of the treatment of bronchopulmonary diseases]. ( de Zeeuw, J; Plomer, M, 2017)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199020 (62.50)18.7374
1990's3 (9.38)18.2507
2000's3 (9.38)29.6817
2010's5 (15.63)24.3611
2020's1 (3.13)2.80

Authors

AuthorsStudies
Meng, F1
Cheng, J1
Sang, P1
Wang, J1
Plomer, M1
de Zeeuw, J1
Deretic, V1
Timmins, GS1
Dey, P1
Banerjee, S1
Mandal, S1
Chattopadhyay, P1
Tam, J1
Nash, EF2
Ratjen, F2
Tullis, E2
Stephenson, A2
Oda, N1
Tamai, K1
Suzuki, Y1
Yoshimatsu, H1
Matsuoka, H1
Matsumoto, Y1
Okada, N1
Ulas, MM1
Hizarci, M1
Kunt, A1
Ergun, K1
Kocabeyoglu, SS1
Korkmaz, K1
Lafci, G1
Gedik, S1
Cagli, K1
PEPYS, J3
WILLIAMS, JV1
DONOGHUE, FE1
SCHMIDT, HW1
HOEER, PW2
LONGBOTTOM, JL1
JENKINS, PA1
KUBASEK, M1
HORBACH, L1
SCHWEISFURTH, R1
LONGBOTTON, JL1
JENKINS, JA1
REIMANN, HA1
Akkoca Yildiz, O1
Shimura, S1
Okubo, T1
Maeda, S1
Aoki, T1
Tomioka, M1
Shindo, Y1
Takishima, T1
Umeya, K1
Gillissen, A1
Nowak, D1
Curti, PC1
Renovanz, HD1
Marcatili, S1
Guarino, C1
Giannattasio, A1
Marcatili, A1
Festa, M1
Cautiero, V1
Marini, MG1
Pierfederici, P1
Dell'Orso, S1
Cotrufo, M1
Luisetti, M1
Peona, V1
Salmona, M1
Pagnoni, AM1
Villani, F1
Knerich, R1
Genghini, M1
Abbà, L1
Pozzi, E1
Winsel, K1
Grollmuss, H1
Unger, U1
Eckert, H1
Solopov, VN1
Kolganova, NA1
Romanini, BM1
Sandri, MG1
Tosi, M1
Mezzetti, M1
Mazzetti, A1
Wilke, A1
Müller, B1
von Wichert, P1

Reviews

5 reviews available for ambroxol and Disease, Pulmonary

ArticleYear
Enhancement of lung levels of antibiotics by ambroxol and bromhexine.
    Expert opinion on drug metabolism & toxicology, 2019, Volume: 15, Issue:3

    Topics: Ambroxol; Animals; Anti-Bacterial Agents; Bacterial Infections; Bromhexine; Drug Resistance, Bacteri

2019
Nebulized and oral thiol derivatives for pulmonary disease in cystic fibrosis.
    The Cochrane database of systematic reviews, 2013, Jul-12, Issue:7

    Topics: Acetylcysteine; Administration, Inhalation; Administration, Oral; Ambroxol; Carbocysteine; Cystic Fi

2013
Nebulized and oral thiol derivatives for pulmonary disease in cystic fibrosis.
    The Cochrane database of systematic reviews, 2009, Jan-21, Issue:1

    Topics: Acetylcysteine; Administration, Inhalation; Administration, Oral; Ambroxol; Carbocysteine; Cystic Fi

2009
[Ambroxol].
    Tuberkuloz ve toraks, 2006, Volume: 54 Suppl 1

    Topics: Ambroxol; Anti-Inflammatory Agents; Antioxidants; Asthma; Bronchial Hyperreactivity; Cystic Fibrosis

2006
Characterization of N-acetylcysteine and ambroxol in anti-oxidant therapy.
    Respiratory medicine, 1998, Volume: 92, Issue:4

    Topics: Acetylcysteine; Ambroxol; Animals; Expectorants; Free Radical Scavengers; Humans; Lung; Lung Disease

1998

Trials

4 trials available for ambroxol and Disease, Pulmonary

ArticleYear
Protective effect of ambroxol on pulmonary function after cardiopulmonary bypass.
    Journal of cardiovascular pharmacology, 2008, Volume: 52, Issue:6

    Topics: Administration, Oral; Adult; Ambroxol; Bronchoalveolar Lavage Fluid; Cardiopulmonary Bypass; Coronar

2008
Effect of expectorants on relaxation behavior of sputum viscoelasticity in vivo.
    Biorheology, 1983, Volume: 20, Issue:5

    Topics: Adult; Aged; Ambroxol; Bromhexine; Chymotrypsin; Elasticity; Expectorants; Female; Humans; Lung Dise

1983
Alterations of the endoalveolar surfactant after surgery with extracorporeal circulation.
    Respiration; international review of thoracic diseases, 1990, Volume: 57, Issue:4

    Topics: Adult; Ambroxol; Bronchoalveolar Lavage Fluid; Chromatography, Thin Layer; Extracorporeal Circulatio

1990
Ambroxol for prophylaxis and treatment of bronchopulmonary complications after chest surgery.
    International journal of clinical pharmacology research, 1986, Volume: 6, Issue:2

    Topics: Adult; Aged; Ambroxol; Bromhexine; Bronchial Diseases; Clinical Trials as Topic; Double-Blind Method

1986

Other Studies

23 other studies available for ambroxol and Disease, Pulmonary

ArticleYear
Effects of Bronchoalveolar Lavage with Ambroxol Hydrochloride on Treating Pulmonary Infection in Patients with Cerebral Infarction and on Serum Proinflammatory Cytokines, MDA and SOD.
    Computational and mathematical methods in medicine, 2020, Volume: 2020

    Topics: Ambroxol; Bronchoalveolar Lavage; Case-Control Studies; Cerebral Infarction; Computational Biology;

2020
[More than expectorant: new scientific data on ambroxol in the context of the treatment of bronchopulmonary diseases].
    MMW Fortschritte der Medizin, 2017, Volume: 159, Issue:Suppl 5

    Topics: Ambroxol; Clinical Trials as Topic; Expectorants; Humans; Lung Diseases; Publications

2017
Design and evaluation of anti-fibrosis drug engineered resealed erythrocytes for targeted delivery.
    Drug delivery and translational research, 2019, Volume: 9, Issue:5

    Topics: Albumins; Ambroxol; Animals; Bronchoalveolar Lavage Fluid; Cytokines; Drug Carriers; Drug Liberation

2019
FARMER'S lung.
    What's new, 1958, Volume: 208

    Topics: Agriculture; Ambroxol; Farmer's Lung; Humans; Lung Diseases; Occupational Diseases

1958
Marked improvement in autoimmune pulmonary alveolar proteinosis with severe hypoxemia in a patient treated with ambroxol: a case report.
    Journal of medical case reports, 2015, May-06, Volume: 9

    Topics: Aged; Ambroxol; Autoimmune Diseases; Expectorants; Female; Granulocyte-Macrophage Colony-Stimulating

2015
FARMER'S lung.
    Lancet (London, England), 1953, May-09, Volume: 1, Issue:6767

    Topics: Agriculture; Ambroxol; Farmer's Lung; Humans; Lung Diseases

1953
FARMER'S lung.
    British medical journal, 1958, Jul-12, Volume: 2, Issue:5088

    Topics: Agriculture; Ambroxol; Farmer's Lung; Lung Diseases; Medical Records; Mycoses; Occupational Diseases

1958
HYPERSENSITIVITY REACTIONS IN MAN TO FUNGI, VEGETABLE DUSTS AND TUBERCULIN.
    Guy's Hospital reports, 1963, Volume: 112

    Topics: Ambroxol; Aspergillosis; Aspergillus; Dust; Farmer's Lung; Fungi; Humans; Hypersensitivity; Lung Dis

1963
PULMONARY FUNCTION STUDIES IN PATIENTS WITH FARMER'S LUNG.
    Thorax, 1963, Volume: 18

    Topics: Agricultural Workers' Diseases; Ambroxol; Farmer's Lung; Humans; Lung Diseases; Respiratory Function

1963
FARMER'S LUNG AND SILO-FILLER'S DISEASE.
    The Medical clinics of North America, 1964, Volume: 48

    Topics: Agricultural Workers' Diseases; Ambroxol; Dust; Farmer's Lung; Gas Poisoning; Humans; Hypersensitivi

1964
[CONTRIBUTION TO THE PATHOGENESIS OF FARMER'S LUNG BASED ON ANIMAL EXPERIMENTS AND ON A CASE OF PRIMARY ACUTE PULMONARY ASPERGILLOSIS].
    Verhandlungen der Deutschen Gesellschaft fur Pathologie, 1963, Volume: 47

    Topics: Adolescent; Agricultural Workers' Diseases; Ambroxol; Animal Experimentation; Animals; Aspergillosis

1963
VEGETABLE DUST PNEUMOCONIOSES. IMMUNOLOGIC RESPONSES TO VEGETABLE DUSTS AND THEIR FLORA.
    The American review of respiratory disease, 1964, Volume: 89

    Topics: Agricultural Workers' Diseases; Ambroxol; Aspergillosis; C-Reactive Protein; Dust; Farmer's Lung; Fu

1964
[FARMER'S LUNG--A MASS OUTBREAK].
    Casopis lekaru ceskych, 1964, Jun-19, Volume: 103

    Topics: Adolescent; Agricultural Workers' Diseases; Ambroxol; Czechoslovakia; Disease Outbreaks; Farmer's Lu

1964
[THE DISEASE PICTURE OF THE FARMER'S LUNG AND ITS RELATION TO FUNGAL INFECTIONS].
    Zeitschrift fur klinische Medizin, 1964, Mar-09, Volume: 158

    Topics: Adolescent; Agricultural Workers' Diseases; Ambroxol; Aspergillosis; Farmer's Lung; Humans; Lung Dis

1964
[PULMONARY ASPERGILLOSIS AND FARMER'S LUNG].
    El Torax, 1964, Volume: 13

    Topics: Allergy and Immunology; Ambroxol; Aspergillosis; Asthma; Eosinophilia; Farmer's Lung; Humans; Immuno

1964
NONMICROBIC PNEUMONIAS AND PNEUMONOSES.
    Biochemical clinics, 1964, Volume: 4

    Topics: Air Pollution; Ambroxol; Asbestosis; Beryllium; Classification; Eosinophilic Granuloma; Farmer's Lun

1964
[Ambroxol. Prophylaxis and therapy of pulmonary complications. Symposium on the occasion of the 12th International Sylt Week on Anesthesiology. 9 September 1998].
    Der Anaesthesist, 1998, Volume: 47, Issue:11 Suppl P

    Topics: Ambroxol; Anesthesia; Dose-Response Relationship, Drug; Expectorants; Humans; Lung Diseases; Medicin

1998
[Therapeutic study on ambroxol in chronic bronchopulmonary diseases (author's transl)].
    Arzneimittel-Forschung, 1978, Volume: 28, Issue:5a

    Topics: Ambroxol; Bromhexine; Bronchitis; Chronic Disease; Cryptococcosis; Humans; Lung Diseases; Lung Disea

1978
Ambroxol and pulmonary toxicity induced by antineoplastic drugs.
    International journal of clinical pharmacology research, 1986, Volume: 6, Issue:2

    Topics: Ambroxol; Animals; Antineoplastic Agents; Bleomycin; Bromhexine; Busulfan; Cyclophosphamide; Humans;

1986
[Modulation of alveolar macrophage activity by ambroxol, bromhexine and exogenous arachidonic acid].
    Zeitschrift fur Erkrankungen der Atmungsorgane, 1985, Volume: 165, Issue:2

    Topics: Ambroxol; Animals; Arachidonic Acid; Arachidonic Acids; Bromhexine; Guinea Pigs; Luminescent Measure

1985
[Effect of lasolvan on mucociliary transport in patients with chronic nonspecific lung diseases].
    Klinicheskaia meditsina, 1988, Volume: 66, Issue:3

    Topics: Adhesiveness; Ambroxol; Bromhexine; Chronic Disease; Drug Evaluation; Humans; Lung Diseases; Mucocil

1988
New aspects in the treatment of pulmonary and upper airways diseases. Proceedings of the satellite symposium to the 4th Congress of the European Society of Pneumology. Milano and Stresa, September 23-28, 1985.
    Respiration; international review of thoracic diseases, 1987, Volume: 51 Suppl 1

    Topics: Ambroxol; Animals; Bromhexine; Humans; Lung Diseases; Respiratory Tract Diseases

1987
Ambroxol increases the choline but not fatty acid incorporation into lung phospholipids in experimental lung disorders.
    Respiration; international review of thoracic diseases, 1987, Volume: 52, Issue:2

    Topics: Ambroxol; Animals; Bromhexine; Choline; Fatty Acids; Female; Lung; Lung Diseases; Male; Peritonitis;

1987