ambroxol has been researched along with Amyotrophic Lateral Sclerosis in 1 studies
Ambroxol: A metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually administered as the hydrochloride.
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bouscary, A | 1 |
| Quessada, C | 1 |
| René, F | 1 |
| Spedding, M | 1 |
| Henriques, A | 1 |
| Ngo, S | 1 |
| Loeffler, JP | 1 |
1 review available for ambroxol and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Drug repositioning in neurodegeneration: An overview of the use of ambroxol in neurodegenerative diseases.
Topics: Ambroxol; Amyotrophic Lateral Sclerosis; Animals; beta-Glucosidase; Disease Models, Animal; Disease | 2020 |