ambroxol has been researched along with Alveolitis, Fibrosing in 8 studies
Ambroxol: A metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually administered as the hydrochloride.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the possible therapeutic effect of ambroxol on pulmonary fibrosis induced by paraquat." | 7.77 | Protective effect of ambroxol against paraquat-induced pulmonary fibrosis in rats. ( Sun, HC; Yang, LT; Zhi, QM, 2011) |
| "To evaluate the possible therapeutic effect of ambroxol on pulmonary fibrosis induced by paraquat." | 3.77 | Protective effect of ambroxol against paraquat-induced pulmonary fibrosis in rats. ( Sun, HC; Yang, LT; Zhi, QM, 2011) |
| " The present study found that: (1) in healthy rats, the ambroxol-induced increase of alveolar antielastase activity did not appear due to reactivation of alpha 1-antitrypsin normally oxidized in the alveolar milieu; (2) in bleomycin-induced pulmonary fibrosis, ambroxol protection reduced total long collagen content at day 28, and (3) in paraquat-induced pulmonary fibrosis, alveolar phospholipids were markedly reduced throughout the 21 days of the experiment." | 3.67 | Relationship between changes in alveolar surfactant levels and lung defence mechanisms. ( Cetta, G; Coccia, P; Donnini, M; Luisetti, M; Pozzi, E; Rossi, A; Salmona, M; Spialtini, L, 1989) |
| " Patients in the treatment group took ambroxol orally at a dosage of 90 mg, three times per day for 3 months from the beginning of radiotherapy." | 2.75 | The protective effects of ambroxol on radiation lung injury and influence on production of transforming growth factor beta1 and tumor necrosis factor alpha. ( Dai, M; Mao, WD; Shen, WS; Shu, ZQ; Xi, L; Xia, DH; Xv, C; Yang, HZ, 2010) |
| "Pulmonary fibrosis is the end point of progressive functional disorder of respiratory mechanism and alveolo-capillary gas exchanges." | 2.66 | Nitrosourea derivatives-induced pulmonary toxicity in patients treated for malignant brain tumors. Early subclinical detection and its prevention. ( Butti, G; Gaetani, P; Knerich, R; Rossi, A; Silvani, V; Spanu, G, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xia, DH | 1 |
| Xi, L | 1 |
| Xv, C | 1 |
| Mao, WD | 1 |
| Shen, WS | 1 |
| Shu, ZQ | 1 |
| Yang, HZ | 1 |
| Dai, M | 1 |
| Zhi, QM | 1 |
| Yang, LT | 1 |
| Sun, HC | 1 |
| VANWORMER, DE | 1 |
| RANKIN, J | 1 |
| KOBAYASHI, M | 1 |
| BARBEE, RA | 1 |
| DICKIE, HA | 1 |
| Luisetti, M | 3 |
| Peona, V | 1 |
| Salmona, M | 3 |
| Pagnoni, AM | 1 |
| Villani, F | 1 |
| Knerich, R | 2 |
| Genghini, M | 2 |
| Abbà, L | 1 |
| Pozzi, E | 3 |
| Masturzo, P | 1 |
| Scelsi, M | 1 |
| Spialtini, L | 2 |
| Coccia, P | 1 |
| Rossi, A | 2 |
| Donnini, M | 1 |
| Cetta, G | 1 |
| Gaetani, P | 1 |
| Silvani, V | 1 |
| Butti, G | 1 |
| Spanu, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Ambroxol on the Inflammatory Markers and Clinical Outcome of Patients With Diabetic Peripheral Neuropathy[NCT05558878] | 80 participants (Anticipated) | Interventional | 2022-10-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for ambroxol and Alveolitis, Fibrosing
| Article | Year |
|---|---|
The protective effects of ambroxol on radiation lung injury and influence on production of transforming growth factor beta1 and tumor necrosis factor alpha.
Topics: Adrenal Cortex Hormones; Adult; Aged; Ambroxol; Carbon Monoxide; Female; Free Radical Scavengers; Hu | 2010 |
Nitrosourea derivatives-induced pulmonary toxicity in patients treated for malignant brain tumors. Early subclinical detection and its prevention.
Topics: Adult; Aged; Ambroxol; Brain Neoplasms; Bromhexine; Carmustine; Clinical Trials as Topic; Double-Bli | 1987 |
6 other studies available for ambroxol and Alveolitis, Fibrosing
| Article | Year |
|---|---|
Protective effect of ambroxol against paraquat-induced pulmonary fibrosis in rats.
Topics: Ambroxol; Animals; Collagen; Cytokines; Disease Models, Animal; Expectorants; Lung; Male; Oxidative | 2011 |
FARMER'S LUNG.
Topics: Ambroxol; Biopsy; Farmer's Lung; Granuloma; Humans; Leukocyte Count; Pathology; Precipitin Tests; Pu | 1965 |
AGRICULTURAL DUSTS AND DIFFUSE PULMONARY FIBROSIS.
Topics: Agricultural Workers' Diseases; Allergy and Immunology; Ambroxol; Dust; Farmer's Lung; Fungi; Humans | 1965 |
Ambroxol and pulmonary toxicity induced by antineoplastic drugs.
Topics: Ambroxol; Animals; Antineoplastic Agents; Bleomycin; Bromhexine; Busulfan; Cyclophosphamide; Humans; | 1986 |
Role of alveolar phospholipids in bleomycin-induced pulmonary fibrosis in the rat.
Topics: Ambroxol; Animals; Bleomycin; Macrophages; Male; Membrane Fluidity; Phosphatidylcholines; Pulmonary | 1987 |
Relationship between changes in alveolar surfactant levels and lung defence mechanisms.
Topics: Ambroxol; Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen; Glutathione; Lung; Macrophage | 1989 |