amatoxin has been researched along with Necrosis* in 1 studies
1 other study(ies) available for amatoxin and Necrosis
Article | Year |
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[A clinical analysis of twelve patients with Galerina autumnalis poisoning].
Twelve patients with Galerina Autumnalis (GA) poisoning were treated. Amatoxin and phallotoxin are the principal toxins of GA. After absorption from intestine into the liver, the toxins combine with RNA polymerase, resulting in block of messenger (mRNA) synthesis, hepatocellular damage, hepatitis, hepatic necrosis, serious coagulation abnormalities and DIC. The clinical characteristics are long latent period, short period of "pseudo-remission" and serious liver dysfunction. These were pathologically confirmed by autopsy. Our experiences with this poisoning are as follows: treatment should be carried out as early as possible, especially with gastric lavage and catharsis and special attention paid to the "pseudo-remission". Topics: Adolescent; Adult; Agaricales; Amanitins; Child; Female; Gastric Lavage; Humans; Liver; Male; Mushroom Poisoning; Necrosis | 1993 |