amantadine has been researched along with Stroke in 9 studies
amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source
Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the efficacy and safety of amantadine sulfate in patients with ischemic stroke." | 9.34 | [The use of amantadine sulfate in ischemic stroke]. ( Akhmatkhanova, LK; Kovaleva, EA; Ramazanov, GR; Shevchenko, EV, 2020) |
| "Amantadine and modafinil are neurostimulants that may improve cognitive and functional recovery post-stroke, but the existing study results vary, and no comprehensive review has been published." | 9.05 | Amantadine and Modafinil as Neurostimulants During Post-stroke Care: A Systematic Review. ( Brown, CS; Cote, J; Eldridge, A; Gagnon, DJ; Leclerc, AM; May, T; Nocella, K; Riker, RR; Seder, DB, 2020) |
| "To assess the efficacy and safety of amantadine sulfate in patients with ischemic stroke." | 5.34 | [The use of amantadine sulfate in ischemic stroke]. ( Akhmatkhanova, LK; Kovaleva, EA; Ramazanov, GR; Shevchenko, EV, 2020) |
| "Amantadine and modafinil are neurostimulants that may improve cognitive and functional recovery post-stroke, but the existing study results vary, and no comprehensive review has been published." | 5.05 | Amantadine and Modafinil as Neurostimulants During Post-stroke Care: A Systematic Review. ( Brown, CS; Cote, J; Eldridge, A; Gagnon, DJ; Leclerc, AM; May, T; Nocella, K; Riker, RR; Seder, DB, 2020) |
| "We pooled individual patient data of five single-centre observational studies to determine the effect of amantadine treatment among patients with ischaemic stroke, intracerebral haemorrhage, subarachnoid haemorrhage, community-acquired bacterial meningitis and status epilepticus, admitted between January 2012 and December 2015 and ventilated ≥7 days." | 4.12 | Amantadine treatment is associated with improved consciousness in patients with non-traumatic brain injury. ( Balk, S; Gerner, ST; Giede-Jeppe, A; Huttner, HB; Jäger, J; Kallmünzer, B; Kuramatsu, JB; Madzar, D; Mueller, T; Rühl, L; Schwab, S; Sembill, JA; Sprügel, MI, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 4 (44.44) | 2.80 |
| Authors | Studies |
|---|---|
| Rühl, L | 1 |
| Kuramatsu, JB | 1 |
| Sembill, JA | 1 |
| Kallmünzer, B | 1 |
| Madzar, D | 1 |
| Gerner, ST | 1 |
| Giede-Jeppe, A | 1 |
| Balk, S | 1 |
| Mueller, T | 1 |
| Jäger, J | 1 |
| Schwab, S | 1 |
| Huttner, HB | 1 |
| Sprügel, MI | 1 |
| Gagnon, DJ | 2 |
| Leclerc, AM | 2 |
| Riker, RR | 2 |
| Brown, CS | 2 |
| May, T | 2 |
| Nocella, K | 2 |
| Cote, J | 2 |
| Eldridge, A | 2 |
| Seder, DB | 2 |
| Ramazanov, GR | 1 |
| Kovaleva, EA | 1 |
| Shevchenko, EV | 1 |
| Akhmatkhanova, LK | 1 |
| Wilcox, SK | 1 |
| Garry, A | 1 |
| Johnson, MJ | 1 |
| Krivonos, OV | 1 |
| Amosova, NA | 1 |
| Smolentseva, IG | 1 |
| Barrett, AM | 1 |
| Levy, CE | 1 |
| Gonzalez Rothi, LJ | 1 |
| Kazui, H | 1 |
| Mori, E | 1 |
| Hashimoto, M | 1 |
| Hirono, N | 1 |
| Satou, T | 1 |
| Wada, H | 1 |
| Arai, H | 1 |
| Sasaki, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Amantadine for Neuroenhancement in Acute Patients Study - A Prospective Pilot Proof of Concept Phase IIb Study in Intensive and Intermediate Care Unit Patients[NCT05479032] | Phase 2 | 50 participants (Anticipated) | Interventional | 2022-09-30 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for amantadine and Stroke
| Article | Year |
|---|---|
Amantadine and Modafinil as Neurostimulants During Post-stroke Care: A Systematic Review.
Topics: Amantadine; Central Nervous System Stimulants; Dopamine Agents; Humans; Modafinil; Recovery of Funct | 2020 |
2 trials available for amantadine and Stroke
| Article | Year |
|---|---|
[The use of amantadine sulfate in ischemic stroke].
Topics: Amantadine; Brain Ischemia; Humans; Ischemic Stroke; Russia; Stroke; Treatment Outcome | 2020 |
Use of the glutamate NMDA receptor antagonist PK-Merz in acute stroke.
Topics: Amantadine; Female; Humans; Male; Middle Aged; Receptors, N-Methyl-D-Aspartate; Stroke | 2010 |
6 other studies available for amantadine and Stroke
| Article | Year |
|---|---|
Amantadine treatment is associated with improved consciousness in patients with non-traumatic brain injury.
Topics: Amantadine; Brain Injuries; Brain Ischemia; Consciousness; Delirium; Glasgow Coma Scale; Humans; Sei | 2022 |
Amantadine and Modafinil as Neurostimulants Following Acute Stroke: A Retrospective Study of Intensive Care Unit Patients.
Topics: Adult; Amantadine; Central Nervous System Stimulants; Humans; Intensive Care Units; Modafinil; Retro | 2021 |
Novel use of amantadine: to treat hiccups.
Topics: Aged; Amantadine; Analgesics, Non-Narcotic; Antidepressive Agents; Fatal Outcome; Hiccup; Humans; Ma | 2009 |
Pharmaceuticals for poststroke and brain injury rehabilitation.
Topics: Amantadine; Aphasia, Broca; Brain Injuries; Dopamine Agents; Humans; Methylphenidate; Persistent Veg | 2007 |
Phobia after bilateral thalamic hemorrhage.
Topics: Amantadine; Cerebral Hemorrhage; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Phobic Disor | 2001 |
[The prevention of pneumonia in the elderly by dopamine agonists].
Topics: Aged; Amantadine; Angiotensin-Converting Enzyme Inhibitors; Dopamine Agonists; Humans; Levodopa; Pne | 2001 |