amantadine has been researched along with Pneumonia, Viral in 24 studies
amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source
Pneumonia, Viral: Inflammation of the lung parenchyma that is caused by a viral infection.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Facing the outbreak of coronavirus disease 2019 (COVID-19) pandemic, there is an urgent need to find protective or curable drugs to prevent or to stop the course of the coronavirus SARS-CoV-2 infection." | 5.56 | Adamantanes might be protective from COVID-19 in patients with neurological diseases: multiple sclerosis, parkinsonism and cognitive impairment. ( Grieb, P; Rejdak, K, 2020) |
| "We treated a woman for influenza pneumonia with respiratory failure at 33 weeks' gestation with oral amantadine and ribavirin inhalation therapy in conjunction with evacuation of the uterus and delivery." | 5.27 | Favorable outcome after treatment with amantadine and ribavirin in a pregnancy complicated by influenza pneumonia. A case report. ( Carpenter, RJ; Faro, S; Kirshon, B; Samo, TC; Zurawin, RK, 1988) |
| " This allowed a total dosage not much less than might have been given by other routes, but with the advantage that it was evenly deposited over the surface of the infected respiratory tract beginning within seconds of the start of treatment and reached higher concentration in nasal secretions than in serum." | 3.76 | Chemotherapy of respiratory viruses. ( Gilbert, BE; Knight, V, 1986) |
| "Although influenza causes a high fever in the elderly similar to that of healthy adults, the cough lasts longer but frequency and degree of sore throat and coryza are lower in the elderly." | 2.42 | [Clinical characteristic of the elderly in influenza infection]. ( Ikematsu, H, 2003) |
| "Amantadine was approved by the US Food and Drug Administration in 1968 as a prophylactic agent for influenza and later for Parkinson's disease." | 1.56 | Amantadine disrupts lysosomal gene expression: A hypothesis for COVID19 treatment. ( Polymeropoulos, MH; Przychodzen, BP; Smieszek, SP, 2020) |
| "Facing the outbreak of coronavirus disease 2019 (COVID-19) pandemic, there is an urgent need to find protective or curable drugs to prevent or to stop the course of the coronavirus SARS-CoV-2 infection." | 1.56 | Adamantanes might be protective from COVID-19 in patients with neurological diseases: multiple sclerosis, parkinsonism and cognitive impairment. ( Grieb, P; Rejdak, K, 2020) |
| "Zanamivir was administered intranasally and amantadine was administered orally." | 1.32 | Compared protective effect of nasal immunoprophylaxis using a new human monoclonal IgM antibody, human polyclonal antibodies, F(ab')2, amantadine, and zanamivir for prophylaxis of influenza A virus pneumonia in mice. ( Bazin, H; Cavallo, JD; Hernandez, E; Lhonneux, A; Noury, J; Ramisse, F, 2003) |
| "Treatment with amantadine hydrochloride and ribavirin was prescribed, and the patient was discharged after 19 days." | 1.29 | Influenza A pneumonitis following treatment of acute cardiac allograft rejection with murine monoclonal anti-CD3 antibody (OKT3). ( Embrey, RP; Geist, LJ, 1995) |
| "We treated a woman for influenza pneumonia with respiratory failure at 33 weeks' gestation with oral amantadine and ribavirin inhalation therapy in conjunction with evacuation of the uterus and delivery." | 1.27 | Favorable outcome after treatment with amantadine and ribavirin in a pregnancy complicated by influenza pneumonia. A case report. ( Carpenter, RJ; Faro, S; Kirshon, B; Samo, TC; Zurawin, RK, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (50.00) | 18.7374 |
| 1990's | 2 (8.33) | 18.2507 |
| 2000's | 3 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 7 (29.17) | 2.80 |
| Authors | Studies |
|---|---|
| Smieszek, SP | 1 |
| Przychodzen, BP | 1 |
| Polymeropoulos, MH | 1 |
| Abreu, GEA | 1 |
| Aguilar, MEH | 1 |
| Covarrubias, DH | 1 |
| Durán, FR | 1 |
| Rejdak, K | 1 |
| Grieb, P | 1 |
| Cortés Borra, A | 1 |
| Tipton, PW | 1 |
| Wszolek, ZK | 1 |
| Wiwanitkit, V | 1 |
| Aranda-Abreu, GE | 1 |
| Hernandez, E | 1 |
| Ramisse, F | 1 |
| Lhonneux, A | 1 |
| Noury, J | 1 |
| Bazin, H | 1 |
| Cavallo, JD | 1 |
| Ikematsu, H | 1 |
| Reichman, RC | 1 |
| Dolin, R | 1 |
| Harris, LF | 1 |
| Fishaut, M | 1 |
| Mostow, SR | 1 |
| Embrey, RP | 1 |
| Geist, LJ | 1 |
| Mahmood, W | 1 |
| Sacks, SL | 1 |
| Otsuka, H | 1 |
| Suzuki, H | 1 |
| Banks, RA | 1 |
| Walker, JS | 1 |
| Stephen, EL | 1 |
| Spertzel, RO | 1 |
| Couch, RB | 1 |
| Jackson, GG | 1 |
| Douglas, RG | 1 |
| Knight, V | 1 |
| Gilbert, BE | 1 |
| Johnson, DC | 1 |
| Kirshon, B | 1 |
| Faro, S | 1 |
| Zurawin, RK | 1 |
| Samo, TC | 1 |
| Carpenter, RJ | 1 |
| Stevens, DA | 1 |
| Rudakova, IS | 1 |
| Chernukh, AM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Amantadine for COVID-19: A Randomized, Placebo Controlled, Double-blinded, Clinical Trial[NCT04894617] | Phase 3 | 226 participants (Anticipated) | Interventional | 2021-06-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for amantadine and Pneumonia, Viral
| Article | Year |
|---|---|
[Clinical characteristic of the elderly in influenza infection].
Topics: Age Factors; Aged; Amantadine; Antiviral Agents; Chromatography; Enzyme Inhibitors; Guanidines; Huma | 2003 |
Viral pneumonias.
Topics: Adenovirus Infections, Human; Adult; Amantadine; Chickenpox; Child; Common Cold; Enterovirus Infecti | 1980 |
Anti-infective therapy for viral pneumonia.
Topics: Acyclovir; Amantadine; Antiviral Agents; Foscarnet; Ganciclovir; Humans; Neuraminidase; Pneumonia, V | 1995 |
[Influenza].
Topics: Age Factors; Amantadine; Antiviral Agents; Databases, Factual; Disease Outbreaks; Encephalitis, Vira | 2001 |
Chemotherapy of respiratory viruses.
Topics: Acyclovir; Adult; Amantadine; Animals; Antiviral Agents; Benzimidazoles; Child; Clinical Trials as T | 1986 |
1 trial available for amantadine and Pneumonia, Viral
| Article | Year |
|---|---|
Chemotherapy of respiratory viruses.
Topics: Acyclovir; Adult; Amantadine; Animals; Antiviral Agents; Benzimidazoles; Child; Clinical Trials as T | 1986 |
19 other studies available for amantadine and Pneumonia, Viral
| Article | Year |
|---|---|
Amantadine disrupts lysosomal gene expression: A hypothesis for COVID19 treatment.
Topics: Amantadine; Antiviral Agents; Betacoronavirus; Cathepsin B; Cathepsin L; Cell Line; Coronavirus Infe | 2020 |
Amantadine as a drug to mitigate the effects of COVID-19.
Topics: Amantadine; Betacoronavirus; Coronavirus Envelope Proteins; Coronavirus Infections; COVID-19; COVID- | 2020 |
Adamantanes might be protective from COVID-19 in patients with neurological diseases: multiple sclerosis, parkinsonism and cognitive impairment.
Topics: Adamantane; Adult; Aged; Aged, 80 and over; Amantadine; Asymptomatic Infections; Betacoronavirus; Co | 2020 |
Does amantadine have a protective effect against COVID-19?
Topics: Amantadine; Betacoronavirus; Coronavirus Infections; COVID-19; Humans; Pandemics; Pneumonia, Viral; | 2020 |
Response to "Does amantadine have a protective effect against COVID-19?"
Topics: Amantadine; Betacoronavirus; Coronavirus Infections; COVID-19; Humans; Pandemics; Pneumonia, Viral; | 2020 |
Amantadine, COVID-19 and Parkinsonism.
Topics: Amantadine; Betacoronavirus; Coronavirus Infections; COVID-19; Humans; Pandemics; Parkinsonian Disor | 2020 |
Response to: Amantadine, COVID-19 and Parkinsonism.
Topics: Amantadine; Betacoronavirus; Coronavirus Infections; COVID-19; Humans; Pandemics; Parkinsonian Disor | 2020 |
Compared protective effect of nasal immunoprophylaxis using a new human monoclonal IgM antibody, human polyclonal antibodies, F(ab')2, amantadine, and zanamivir for prophylaxis of influenza A virus pneumonia in mice.
Topics: Amantadine; Animals; Antibodies, Monoclonal; Antiviral Agents; Female; Guanidines; Humans; Immunizat | 2003 |
Influenza--a reminder.
Topics: Adolescent; Adult; Amantadine; Female; Humans; Influenza A virus; Influenza B virus; Influenza, Huma | 1984 |
Amantadine for severe influenza A pneumonia in infancy.
Topics: Amantadine; Female; Humans; Infant; Influenza A virus; Influenza, Human; Pneumonia, Viral; Tissue Di | 1980 |
Influenza A pneumonitis following treatment of acute cardiac allograft rejection with murine monoclonal anti-CD3 antibody (OKT3).
Topics: Amantadine; Antiviral Agents; Graft Rejection; Heart Transplantation; Humans; Immunocompromised Host | 1995 |
The enigma of influenzal pneumonia.
Topics: Adrenal Cortex Hormones; Amantadine; Anti-Bacterial Agents; Bacterial Infections; Humans; Influenza | 1978 |
Small-particle aerosols of antiviral compounds in treatment of type A influenza pneumonia in mice.
Topics: Administration, Intranasal; Aerosols; Amantadine; Animals; Antiviral Agents; Female; Injections, Int | 1976 |
Antiviral agents in influenza--summary of Influenza Workshop VIII.
Topics: Amantadine; Animals; Antiviral Agents; Drug Evaluation; Humans; Influenza, Human; Interferon Inducer | 1976 |
Influenza: the disease and its complications.
Topics: Amantadine; Aspirin; Bacterial Infections; Bronchitis; Central Nervous System Diseases; Cross Infect | 1976 |
Antiviral drugs for common respiratory diseases. What's here, what's to come.
Topics: Adult; Aged; Amantadine; Antiviral Agents; Child; Female; Humans; Infant; Infant, Newborn; Influenza | 1988 |
Favorable outcome after treatment with amantadine and ribavirin in a pregnancy complicated by influenza pneumonia. A case report.
Topics: Adult; Amantadine; Drug Therapy, Combination; Female; Humans; Infant, Newborn; Influenza A virus; In | 1988 |
Viral and mycoplasma pneumonias.
Topics: Amantadine; Anti-Bacterial Agents; Antiviral Agents; Chickenpox; Humans; Influenza Vaccines; Influen | 1974 |
Changes in the state of the microvascular bed and in the extent of transcapillary exchange by preparations with P-vitamin activity.
Topics: Amantadine; Animals; Capillaries; Capillary Permeability; Coronary Disease; Coumarins; Flavonoids; F | 1969 |