amantadine has been researched along with Pain in 15 studies
amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An aim of a study was to establish the relationship between pain, motor complications and depression in Parkinson's disease and evaluate an effect of the 3 months therapy with the dopamine receptor agonist pramipexole (mirapex)." | 9.13 | [Pain and depression in Parkinson's disease: new therapeutic possibilities of pramipexole]. ( Letvinenko, IV; Mogil'naia, VI; Odinak, MM, 2008) |
| "Our study has shown that intravenous amantadine is beneficial in reducing the pain of painful peripheral neuropathy, with an effect sustained for at least 1 week after an infusion." | 9.10 | A pilot study of the beneficial effects of amantadine in the treatment of painful diabetic peripheral neuropathy. ( Amin, P; Sturrock, ND, 2003) |
| "A double-blind, placebo-controlled trial of amantadine hydrochloride (Symmetrel) in acute herpes zoster (shingles) was carried out in 100 patients in general practice." | 9.04 | Treatment of acute herpes zoster with amantadine hydrochloride (Symmetrel). ( Galbraith, AW, 1973) |
| "An aim of a study was to establish the relationship between pain, motor complications and depression in Parkinson's disease and evaluate an effect of the 3 months therapy with the dopamine receptor agonist pramipexole (mirapex)." | 5.13 | [Pain and depression in Parkinson's disease: new therapeutic possibilities of pramipexole]. ( Letvinenko, IV; Mogil'naia, VI; Odinak, MM, 2008) |
| "Our study has shown that intravenous amantadine is beneficial in reducing the pain of painful peripheral neuropathy, with an effect sustained for at least 1 week after an infusion." | 5.10 | A pilot study of the beneficial effects of amantadine in the treatment of painful diabetic peripheral neuropathy. ( Amin, P; Sturrock, ND, 2003) |
| "A double-blind, placebo-controlled trial of amantadine hydrochloride (Symmetrel) in acute herpes zoster (shingles) was carried out in 100 patients in general practice." | 5.04 | Treatment of acute herpes zoster with amantadine hydrochloride (Symmetrel). ( Galbraith, AW, 1973) |
| "In the course of 3 years we observed a considerable improvement of herpes zoster in 44 patients being treated with amantadine." | 3.66 | [Improvement of zoster therapy by adamantine]. ( Barolin, GS; Saurugg, D; Zechner, G, 1978) |
| "Morphine was measured in serum of amantadine or vehicle treated rats to search for possible pharmacokinetic interactions between amantadine and morphine." | 1.33 | Effects of pre-treatment with amantadine on morphine induced antinociception during second phase formalin responses in rats. ( Meert, TF; Snijdelaar, DG; van Rijn, CM; Vinken, P, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (20.00) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 7 (46.67) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Childers, WE | 1 |
| Baudy, RB | 1 |
| Takeda, A | 1 |
| Letvinenko, IV | 1 |
| Odinak, MM | 1 |
| Mogil'naia, VI | 1 |
| Suski, M | 1 |
| Bujak-Gizycka, B | 1 |
| Madej, J | 1 |
| Olszanecki, R | 1 |
| Korbut, R | 1 |
| Siao, KT | 1 |
| Pypendop, BH | 1 |
| Escobar, A | 1 |
| Stanley, SD | 1 |
| Ilkiw, JE | 1 |
| Amin, P | 1 |
| Sturrock, ND | 1 |
| Karadag, HC | 1 |
| Ulugol, A | 1 |
| Tamer, M | 1 |
| Ipci, Y | 1 |
| Dokmeci, I | 1 |
| Inomata, S | 1 |
| Kakiuchi, Y | 1 |
| Miyabe, M | 1 |
| Ohara, Y | 1 |
| Sukegawa, I | 1 |
| Osaka, Y | 1 |
| Kohda, Y | 1 |
| Toyooka, H | 1 |
| Snijdelaar, DG | 1 |
| van Rijn, CM | 1 |
| Vinken, P | 1 |
| Meert, TF | 1 |
| Eisenberg, E | 1 |
| Pud, D | 1 |
| Taira, T | 1 |
| Barolin, GS | 1 |
| Saurugg, D | 1 |
| Zechner, G | 1 |
| Chiba, S | 1 |
| Ito, M | 1 |
| Matsumoto, H | 1 |
| Galbraith, AW | 1 |
| Delwaide, PJ | 1 |
| Schwab, RS | 1 |
| Young, RR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Controlled Phase II, Two-Arm Study of Umbilical Cord Blood Cell Transplant (MC001) Into Injured Spinal Cord Followed by the Locomotor Training for Patients With Chronic Complete Spinal Cord Injuries (SCI).[NCT03979742] | Phase 2 | 18 participants (Anticipated) | Interventional | 2022-02-22 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for amantadine and Pain
| Article | Year |
|---|---|
N-methyl-D-aspartate antagonists and neuropathic pain: the search for relief.
Topics: Analgesics; Analgesics, Opioid; Animals; Binding Sites; Glycine; Humans; Ion Channel Gating; Pain; P | 2007 |
4 trials available for amantadine and Pain
| Article | Year |
|---|---|
[Pain and depression in Parkinson's disease: new therapeutic possibilities of pramipexole].
Topics: Aged; Amantadine; Benzothiazoles; Depressive Disorder, Major; Dopamine Agonists; Drug Therapy, Combi | 2008 |
Effect of amantadine on oxymorphone-induced thermal antinociception in cats.
Topics: Amantadine; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Cats; Dose-Response Relationship, | 2012 |
A pilot study of the beneficial effects of amantadine in the treatment of painful diabetic peripheral neuropathy.
Topics: Adolescent; Adult; Aged; Amantadine; Analgesics, Non-Narcotic; Diabetic Neuropathies; Female; Humans | 2003 |
Treatment of acute herpes zoster with amantadine hydrochloride (Symmetrel).
Topics: Adolescent; Adult; Age Factors; Aged; Amantadine; Clinical Trials as Topic; Complement Fixation Test | 1973 |
10 other studies available for amantadine and Pain
| Article | Year |
|---|---|
[Parkinson's Disease with Intolerable Painful Dyskinesia: Standard Treatment and Subsequent Tips].
Topics: Amantadine; Antiparkinson Agents; Dyskinesia, Drug-Induced; Humans; Levodopa; Pain; Parkinson Diseas | 2022 |
[Evaluation of morphine metabolism in presence of amantadine and dextromethorphan in human serum by high performance liquid chromatography coupled with mass spectrometry (LC/MS) method].
Topics: Amantadine; Analgesics, Non-Narcotic; Analgesics, Opioid; Chromatography, High Pressure Liquid; Dext | 2008 |
Systemic agmatine attenuates tactile allodynia in two experimental neuropathic pain models in rats.
Topics: Amantadine; Analgesics, Non-Narcotic; Animals; Diabetic Neuropathies; Female; Ligation; Male; Pain; | 2003 |
Combined therapy with clonidine and amantadine may act in two stages of glutamate-mediated neuropathic pain caused by a needle puncture in an upper extremity.
Topics: Adrenergic alpha-Agonists; Adult; Amantadine; Analgesics, Non-Narcotic; Calcium Channel Blockers; Ca | 2005 |
Effects of pre-treatment with amantadine on morphine induced antinociception during second phase formalin responses in rats.
Topics: Amantadine; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Dose-Response Relatio | 2005 |
Can patients with chronic neuropathic pain be cured by acute administration of the NMDA receptor antagonist amantadine?
Topics: Aged; Amantadine; Analgesics, Non-Narcotic; Chronic Disease; Excitatory Amino Acid Antagonists; Fema | 1998 |
Comments on Eisenberg and Pud, PAIN, 74 (1998) 337-339.
Topics: Amantadine; Analgesics, Non-Narcotic; Humans; Nervous System Diseases; Pain | 1998 |
[Improvement of zoster therapy by adamantine].
Topics: Adult; Amantadine; Female; Herpes Zoster; Humans; Infusions, Parenteral; Male; Pain | 1978 |
Amantadine treatment for refractory pain and fatigue in patients with multiple sclerosis.
Topics: Adult; Amantadine; Fatigue; Female; Humans; Male; Multiple Sclerosis; Pain | 1992 |
Polysynaptic spinal reflexes in Parkinson's disease.
Topics: Aged; Amantadine; Dihydroxyphenylalanine; Drug Combinations; Electromyography; Female; Humans; Male; | 1974 |