amantadine has been researched along with Pain, Postoperative in 7 studies
amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source
Pain, Postoperative: Pain during the period after surgery.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A remifentanil infusion was started at a rate of 0." | 2.79 | Influence of high-dose intraoperative remifentanil with or without amantadine on postoperative pain intensity and morphine consumption in major abdominal surgery patients: a randomised trial. ( Klambeck, M; Kopf, A; Mousa, SA; Schäfer, M; Treskatsch, S, 2014) |
| "Amantadine is known to be a noncompetitive N-methyl-D-aspartate receptor antagonist and may be useful in preventing postoperative central sensitization, acute opioid tolerance, and opioid-induced hyperalgesia, thereby decreasing pain and analgesic requirements." | 2.71 | Effects of perioperative oral amantadine on postoperative pain and morphine consumption in patients after radical prostatectomy: results of a preliminary study. ( Katz, J; Koren, G; Snijdelaar, DG, 2004) |
| "Because of no differences in postoperative pain or opioid consumption, we conclude that a preoperative dose of 200 mg amantadine IV fails to enhance postoperative analgesia in patients undergoing elective abdominal hysterectomy." | 2.70 | Amantadine, a N-methyl-D-aspartate receptor antagonist, does not enhance postoperative analgesia in women undergoing abdominal hysterectomy. ( Buerkle, H; Gottschalk, A; Oncü, A; Schroeder, F; Standl, T; Ufer, M, 2001) |
| "The study sample consisted of 15 cancer patients with the diagnosis of surgical neuropathic pain." | 2.69 | The NMDA receptor antagonist amantadine reduces surgical neuropathic pain in cancer patients: a double blind, randomized, placebo controlled trial. ( Adler, R; Eisenberg, E; Fried, G; Pud, D; Spitzer, A; Yarnitsky, D, 1998) |
| "Three types of hyperalgesia can occur during the postoperative period: primary hyperalgesia, which disappears with wound healing, secondary or central hyperalgesia, which can lead to chronic pain, and opiate-induced hyperalgesia." | 2.48 | [Prevention of postoperative hyperalgesia]. ( Mamie, C, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Treskatsch, S | 1 |
| Klambeck, M | 1 |
| Mousa, SA | 1 |
| Kopf, A | 1 |
| Schäfer, M | 1 |
| Mamie, C | 1 |
| Bujak-Giżycka, B | 1 |
| Kącka, K | 1 |
| Suski, M | 1 |
| Olszanecki, R | 1 |
| Madej, J | 1 |
| Dobrogowski, J | 1 |
| Korbut, R | 1 |
| Snijdelaar, DG | 1 |
| Koren, G | 1 |
| Katz, J | 1 |
| Eisenberg, E | 2 |
| Pud, D | 2 |
| Koltun, L | 1 |
| Loven, D | 1 |
| Spitzer, A | 1 |
| Adler, R | 1 |
| Fried, G | 1 |
| Yarnitsky, D | 1 |
| Gottschalk, A | 1 |
| Schroeder, F | 1 |
| Ufer, M | 1 |
| Oncü, A | 1 |
| Buerkle, H | 1 |
| Standl, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phenomics and Genomics of Clinically Relevant Chronic Postsurgical Pain: A Multicenter Prospective Study[NCT04798573] | 10,000 participants (Anticipated) | Observational | 2012-08-03 | Active, not recruiting | |||
| The Implications of Amantadine Sulphate Usage in Spine Deformities Corrective Surgeries Patients as Regard Its Effect on the Duration of Wake up Test and Postoperative Opioid Consumption[NCT03178708] | Phase 2/Phase 3 | 60 participants (Actual) | Interventional | 2017-08-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for amantadine and Pain, Postoperative
| Article | Year |
|---|---|
[Prevention of postoperative hyperalgesia].
Topics: Amantadine; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Excit | 2012 |
6 trials available for amantadine and Pain, Postoperative
| Article | Year |
|---|---|
Influence of high-dose intraoperative remifentanil with or without amantadine on postoperative pain intensity and morphine consumption in major abdominal surgery patients: a randomised trial.
Topics: Abdomen; Aged; Amantadine; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Female | 2014 |
Beneficial effect of amantadine on postoperative pain reduction and consumption of morphine in patients subjected to elective spine surgery.
Topics: Adolescent; Amantadine; Analgesics, Non-Narcotic; Anesthetics, Intravenous; Double-Blind Method; Fem | 2012 |
Effects of perioperative oral amantadine on postoperative pain and morphine consumption in patients after radical prostatectomy: results of a preliminary study.
Topics: Adolescent; Adult; Aged; Amantadine; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Gener | 2004 |
Effects of perioperative oral amantadine on postoperative pain and morphine consumption in patients after radical prostatectomy: results of a preliminary study.
Topics: Adolescent; Adult; Aged; Amantadine; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Gener | 2004 |
Effects of perioperative oral amantadine on postoperative pain and morphine consumption in patients after radical prostatectomy: results of a preliminary study.
Topics: Adolescent; Adult; Aged; Amantadine; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Gener | 2004 |
Effects of perioperative oral amantadine on postoperative pain and morphine consumption in patients after radical prostatectomy: results of a preliminary study.
Topics: Adolescent; Adult; Aged; Amantadine; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Gener | 2004 |
Effect of early administration of the N-methyl-d-aspartate receptor antagonist amantadine on the development of postmastectomy pain syndrome: a prospective pilot study.
Topics: Adolescent; Adult; Aged; Amantadine; Analgesics, Non-Narcotic; Analysis of Variance; Breast Diseases | 2007 |
The NMDA receptor antagonist amantadine reduces surgical neuropathic pain in cancer patients: a double blind, randomized, placebo controlled trial.
Topics: Adult; Aged; Amantadine; Analgesics, Non-Narcotic; Double-Blind Method; Female; Hot Temperature; Hum | 1998 |
Amantadine, a N-methyl-D-aspartate receptor antagonist, does not enhance postoperative analgesia in women undergoing abdominal hysterectomy.
Topics: Aged; Amantadine; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Double-Blind Me | 2001 |