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amantadine and Neoplasms

amantadine has been researched along with Neoplasms in 13 studies

amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
" We included studies investigating pemoline and modafinil in participants with multiple sclerosis (MS)-associated fatigue and methylphenidate in patients suffering from advanced cancer and fatigue in meta-analysis."4.91Pharmacological treatments for fatigue associated with palliative care. ( Cuhls, H; Minton, O; Mücke, M; Peuckmann-Post, V; Radbruch, L; Stone, P, 2015)
" Studies investigating amantadine, pemoline, and modafinil in participants with Multiple Sclerosis (MS)-associated fatigue and methylphenidate in patients suffering from advanced cancer and fatigue could be used for meta-analysis."4.86Pharmacological treatments for fatigue associated with palliative care. ( Elsner, F; Krumm, N; Peuckmann, V; Radbruch, L; Trottenberg, P, 2010)
"The study sample consisted of 15 cancer patients with the diagnosis of surgical neuropathic pain."2.69The NMDA receptor antagonist amantadine reduces surgical neuropathic pain in cancer patients: a double blind, randomized, placebo controlled trial. ( Adler, R; Eisenberg, E; Fried, G; Pud, D; Spitzer, A; Yarnitsky, D, 1998)
"However, many cancer cells are resistant to death receptor-mediated apoptosis."1.37Cisplatin and a potent platinum(IV) complex-mediated enhancement of TRAIL-induced cancer cells killing is associated with modulation of upstream events in the extrinsic apoptotic pathway. ( Andera, L; Hofmanová, J; Horváth, V; Jelínková, I; Kozubík, A; Skender, B; Soucek, K; Sova, P; Szöllosi, J; Szöor, A; Vaculová, A; Vereb, G; Vondálová Blanárová, O, 2011)
"Amantadine prophylaxis was performed in 91 patients during influenza A epidemics."1.29[Amantadine in the prevention of nosocomial influenza]. ( Bíró, L; Guller, Z; Koltai, M; Szepesi, A, 1996)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19904 (30.77)18.7374
1990's3 (23.08)18.2507
2000's0 (0.00)29.6817
2010's5 (38.46)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Ali, EMH1
Abdel-Maksoud, MS1
Oh, CH1
Li, L1
Liu, M1
Yue, L1
Wang, R2
Zhang, N1
Liang, Y1
Zhang, L1
Cheng, L1
Xia, J1
Shaili, E1
Mücke, M1
Cuhls, H1
Peuckmann-Post, V1
Minton, O1
Stone, P1
Radbruch, L2
Vondálová Blanárová, O1
Jelínková, I1
Szöor, A1
Skender, B1
Soucek, K1
Horváth, V1
Vaculová, A1
Andera, L1
Sova, P1
Szöllosi, J1
Hofmanová, J1
Vereb, G1
Kozubík, A1
Peuckmann, V1
Elsner, F1
Krumm, N1
Trottenberg, P1
Galasso, GJ1
White, DO1
Bíró, L1
Guller, Z1
Koltai, M1
Szepesi, A1
Pud, D1
Eisenberg, E1
Spitzer, A1
Adler, R1
Fried, G1
Yarnitsky, D1
Schepetiuk, S1
Papanaoum, K1
Qiao, M1
Orgogozo, JM1
Loiseau, P1
Frohberg, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Feasibility Study of Adjunctive Bright Light Therapy (BLT) for Amelioration of Fatigue in Chinese Cancer Patients Admitted to a Palliative Care Unit[NCT04525924]42 participants (Anticipated)Interventional2020-08-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

8 reviews available for amantadine and Neoplasms

ArticleYear
Thieno[2,3-d]pyrimidine as a promising scaffold in medicinal chemistry: Recent advances.
    Bioorganic & medicinal chemistry, 2019, 04-01, Volume: 27, Issue:7

    Topics: Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Chemistry, Ph

2019
Platinum anticancer drugs and photochemotherapeutic agents: recent advances and future developments.
    Science progress, 2014, Volume: 97, Issue:Pt 1

    Topics: Amantadine; Antineoplastic Agents; Cisplatin; Clinical Trials as Topic; Humans; Light; Neoplasms; Or

2014
Pharmacological treatments for fatigue associated with palliative care.
    The Cochrane database of systematic reviews, 2015, May-30, Issue:5

    Topics: Adult; Amantadine; Benzhydryl Compounds; Carnitine; Central Nervous System Stimulants; Chronic Disea

2015
Pharmacological treatments for fatigue associated with palliative care.
    The Cochrane database of systematic reviews, 2010, Nov-10, Issue:11

    Topics: Adult; Amantadine; Benzhydryl Compounds; Central Nervous System Stimulants; Fatigue; Humans; Kidney

2010
Antiviral agents: the road from scepticism to efficacy.
    Acta microbiologica Academiae Scientiarum Hungaricae, 1981, Volume: 28, Issue:3

    Topics: Acyclovir; Amantadine; Antiviral Agents; Bromodeoxyuridine; Clinical Trials as Topic; Guanine; Hepat

1981
Antiviral chemotherapy.
    The Medical journal of Australia, 1984, Jun-09, Volume: 140, Issue:12

    Topics: Acyclovir; Amantadine; Animals; Antiviral Agents; Bromodeoxyuridine; Female; Hepatitis B; Herpes Gen

1984
[Teratogenic and oncogenic effects of central nervous system drugs].
    La Revue du praticien, 1977, Jun-21, Volume: 27, Issue:35

    Topics: Abnormalities, Drug-Induced; Amantadine; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepi

1977
[Present position of the toxicology of drugs].
    Munchener medizinische Wochenschrift (1950), 1970, Aug-28, Volume: 112, Issue:35

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Amantadine; Aminopterin; Animals; Animals, Newbo

1970

Trials

2 trials available for amantadine and Neoplasms

ArticleYear
Antiviral agents: the road from scepticism to efficacy.
    Acta microbiologica Academiae Scientiarum Hungaricae, 1981, Volume: 28, Issue:3

    Topics: Acyclovir; Amantadine; Antiviral Agents; Bromodeoxyuridine; Clinical Trials as Topic; Guanine; Hepat

1981
The NMDA receptor antagonist amantadine reduces surgical neuropathic pain in cancer patients: a double blind, randomized, placebo controlled trial.
    Pain, 1998, Volume: 75, Issue:2-3

    Topics: Adult; Aged; Amantadine; Analgesics, Non-Narcotic; Double-Blind Method; Female; Hot Temperature; Hum

1998

Other Studies

4 other studies available for amantadine and Neoplasms

ArticleYear
Host-Guest Protein Assembly for Affinity Purification of Methyllysine Proteomes.
    Analytical chemistry, 2020, 07-07, Volume: 92, Issue:13

    Topics: Amantadine; Bridged-Ring Compounds; Chromatography, Affinity; Chromobox Protein Homolog 5; Chromosom

2020
Cisplatin and a potent platinum(IV) complex-mediated enhancement of TRAIL-induced cancer cells killing is associated with modulation of upstream events in the extrinsic apoptotic pathway.
    Carcinogenesis, 2011, Volume: 32, Issue:1

    Topics: Amantadine; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Separation; Cisplatin; Flow Cytomet

2011
[Amantadine in the prevention of nosocomial influenza].
    Orvosi hetilap, 1996, Jan-28, Volume: 137, Issue:4

    Topics: Aged; Amantadine; Antiviral Agents; Cardiovascular Diseases; Chronic Disease; Cross Infection; Diabe

1996
Spread of influenza A virus infection in hospitalised patients with cancer.
    Australian and New Zealand journal of medicine, 1998, Volume: 28, Issue:4

    Topics: Adult; Aged; Amantadine; Antiviral Agents; Cross Infection; Disease Outbreaks; Female; Humans; Immun

1998