amantadine has been researched along with Muscle Rigidity in 26 studies
amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source
Muscle Rigidity: Continuous involuntary sustained muscle contraction which is often a manifestation of BASAL GANGLIA DISEASES. When an affected muscle is passively stretched, the degree of resistance remains constant regardless of the rate at which the muscle is stretched. This feature helps to distinguish rigidity from MUSCLE SPASTICITY. (From Adams et al., Principles of Neurology, 6th ed, p73)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A paranoid schizophrenic patient developed the neuroleptic malignant syndrome after receiving three doses of fluphenazine HCl and two doses of thioridazine while he was recovering from major trauma." | 7.66 | A case of neuroleptic malignant syndrome successfully treated with amantadine. ( Boettger, ML; McCarron, MM; Peck, JJ, 1982) |
| "A paranoid schizophrenic patient developed the neuroleptic malignant syndrome after receiving three doses of fluphenazine HCl and two doses of thioridazine while he was recovering from major trauma." | 3.66 | A case of neuroleptic malignant syndrome successfully treated with amantadine. ( Boettger, ML; McCarron, MM; Peck, JJ, 1982) |
| " Dextroamphetamine in lower dosage also reduced disability by some 17 percent." | 2.64 | Amphetamines in the treatment of Parkinson's disease. ( Asselman, P; Bovill, KT; Marsden, CD; Parkes, JD; Phipps, JA; Rose, P; Tarsy, D, 1975) |
| " This case report serves as a reminder of the importance that patients receive their anti-Parkinsonian medications perioperatively, and highlights the potential benefits of inserting a gastric tube to continue anti-Parkinson's medication dosing during prolonged surgery." | 1.37 | Nasogastric medication for perioperative Parkinson's rigidity during anaesthesia emergence. ( Grice, T; Stagg, P, 2011) |
| "This article gives an overview of Parkinson's disease, a common neurological disorder." | 1.27 | Comprehensive care of the patient with Parkinson's disease. ( Bratton, M; Jost, MG; Lannon, MC; Lockhart-Pretti, P; Thomas, CA, 1986) |
| "Twenty-seven patients with Parkinson's disease participated in a double-blind crossover trial of L-dopa and amantadine." | 1.25 | Interactions of L-dopa and amantadine in patients with Parkinsonism. ( Cox, B; Danta, G; Schnieden, H; Yuill, GM, 1973) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (84.62) | 18.7374 |
| 1990's | 1 (3.85) | 18.2507 |
| 2000's | 2 (7.69) | 29.6817 |
| 2010's | 1 (3.85) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brantley, E | 1 |
| Cohn, J | 1 |
| Babu, K | 1 |
| Stagg, P | 1 |
| Grice, T | 1 |
| Takahashi, H | 1 |
| Shinohara, Y | 1 |
| Fann, WE | 1 |
| Lake, CR | 1 |
| Neppe, VM | 1 |
| Lazarus, A | 1 |
| Pirovino, M | 1 |
| Meier, J | 1 |
| Meyer, M | 1 |
| Waldmeier, P | 1 |
| Schmid, M | 1 |
| McCarron, MM | 1 |
| Boettger, ML | 1 |
| Peck, JJ | 1 |
| Przuntek, H | 1 |
| Butzer, JF | 1 |
| Silver, DE | 1 |
| Sahs, AL | 1 |
| Parkes, JD | 1 |
| Tarsy, D | 1 |
| Marsden, CD | 1 |
| Bovill, KT | 1 |
| Phipps, JA | 1 |
| Rose, P | 1 |
| Asselman, P | 1 |
| Calne, DB | 1 |
| Goldstein, JM | 1 |
| Barnett, A | 1 |
| Malick, JB | 1 |
| Nakashima, K | 1 |
| Takahashi, K | 1 |
| Lannon, MC | 1 |
| Thomas, CA | 1 |
| Bratton, M | 1 |
| Jost, MG | 1 |
| Lockhart-Pretti, P | 1 |
| Weinger, MB | 1 |
| Sanford, TJ | 1 |
| Smith, NT | 1 |
| Abbott, RJ | 1 |
| Loizou, LA | 1 |
| Silbert, BS | 1 |
| Vacanti, CA | 1 |
| Sontag, KH | 1 |
| Wand, P | 1 |
| Klawans, HL | 1 |
| Topel, JL | 1 |
| Ngai, SH | 1 |
| Ahtee, L | 1 |
| Kääriäinen, I | 1 |
| Paasonen, MK | 1 |
| Cox, B | 1 |
| Danta, G | 1 |
| Schnieden, H | 1 |
| Yuill, GM | 1 |
| Dooling, EC | 1 |
| Schoene, WC | 1 |
| Richardson, EP | 1 |
| Chase, TN | 1 |
| Woods, AC | 1 |
| Glaubiger, GA | 1 |
| Bauer, RB | 1 |
| McHenry, JT | 1 |
5 reviews available for amantadine and Muscle Rigidity
| Article | Year |
|---|---|
[Diagnosis and therapy for patients with vascular parkinsonism].
Topics: Akinetic Mutism; Amantadine; Antiparkinson Agents; Cerebral Infarction; Dementia, Vascular; Diagnosi | 2003 |
[Therapy of tparkinson's disease. Clinical and pharmacological viewpoints].
Topics: Adrenergic beta-Antagonists; Amantadine; Bromocriptine; Histamine H1 Antagonists; Humans; Levodopa; | 1979 |
Drug treatment of spasticity and rigidity.
Topics: Amantadine; Baclofen; Diazepam; Humans; Levodopa; Mephenesin; Muscle Rigidity; Parasympatholytics; P | 1975 |
Neuroleptic malignant syndrome.
Topics: Adult; Amantadine; Animals; Body Temperature; Bromocriptine; Dantrolene; Diagnosis, Differential; Fe | 1986 |
Parkinsonism, levodopa, and anesthesia.
Topics: Amantadine; Anesthesia; Animals; Apomorphine; Benperidol; Blood-Brain Barrier; Brain; Cardiovascular | 1972 |
5 trials available for amantadine and Muscle Rigidity
| Article | Year |
|---|---|
On the coexistence of parkinsonism and tardive dyskinesia.
Topics: Amantadine; Antiparkinson Agents; Cross-Over Studies; Double-Blind Method; Dyskinesia, Drug-Induced; | 1974 |
Amantadine in Parkinson's disease. A double-blind, placebo-controlled, crossover study with long-term follow-up.
Topics: Activities of Daily Living; Aged; Amantadine; Benztropine; Clinical Trials as Topic; Diphenhydramine | 1975 |
Amphetamines in the treatment of Parkinson's disease.
Topics: Aged; Amantadine; Amphetamine; Clinical Trials as Topic; Female; Humans; Isomerism; Levodopa; Male; | 1975 |
Parkinson disease treated with a suspected dopamine receptor agonist.
Topics: Adult; Aged; Amantadine; Aromatic Amino Acid Decarboxylase Inhibitors; Benztropine; Dihydroxyphenyla | 1974 |
Comparison of amantadine, placebo, and levodopa in Parkinson's disease.
Topics: Aged; Amantadine; Dihydroxyphenylalanine; Evaluation Studies as Topic; Female; Humans; Male; Middle | 1974 |
16 other studies available for amantadine and Muscle Rigidity
| Article | Year |
|---|---|
Case files of the program in medical toxicology at brown university: amantadine withdrawal and the neuroleptic malignant syndrome.
Topics: Amantadine; Antipsychotic Agents; Diagnosis, Differential; Drug Therapy, Combination; Female; Fluid | 2009 |
Nasogastric medication for perioperative Parkinson's rigidity during anaesthesia emergence.
Topics: Amantadine; Anesthesia; Anesthesia Recovery Period; Anesthesia, General; Antiparkinson Agents; Carbi | 2011 |
The neuroleptic malignant syndrome. A priority system.
Topics: Amantadine; Antipsychotic Agents; Basal Ganglia Diseases; Bromocriptine; Consciousness Disorders; Da | 1984 |
Treating neuroleptic malignant syndrome.
Topics: Amantadine; Antipsychotic Agents; Bromocriptine; Dantrolene; Fever; Humans; Muscle Rigidity | 1984 |
[Malignant neuroleptics syndrome].
Topics: Adult; Amantadine; Baclofen; Cerebrospinal Fluid; Chromatography, Liquid; Cognition Disorders; Femal | 1984 |
A case of neuroleptic malignant syndrome successfully treated with amantadine.
Topics: Adult; Amantadine; Consciousness Disorders; Fluphenazine; Humans; Male; Malignant Hyperthermia; Musc | 1982 |
The evaluation of anti-parkinson drugs on reserpine-induced rigidity in rats.
Topics: Amantadine; Animals; Antiparkinson Agents; Apomorphine; Benztropine; Carbidopa; Hindlimb; Levodopa; | 1975 |
Exteroceptive suppression of the masseter and temporalis muscles and parkinsonian rigidity.
Topics: Adult; Aged; Amantadine; Basal Ganglia; Bromocriptine; Electric Stimulation; Electromyography; Femal | 1991 |
Comprehensive care of the patient with Parkinson's disease.
Topics: Aged; Amantadine; Bromocriptine; Carbidopa; Drug Combinations; Humans; Levodopa; Male; Muscle Rigidi | 1986 |
Do dopaminergic drugs really prevent opiate-induced rigidity?
Topics: Amantadine; Diazepam; Dopamine; Humans; Muscle Rigidity; Narcotics | 1988 |
Amantidine in prevention of fentanyl-induced muscle rigidity.
Topics: Amantadine; Female; Fentanyl; Humans; Middle Aged; Muscle Rigidity | 1987 |
Decrease of muscle rigidity by dimethylaminoadamantan (DMMA) in intercollicularly decerebrated cats.
Topics: Amantadine; Animals; Cats; Cell Membrane Permeability; Decerebrate State; Dimethylamines; Drug Evalu | 1973 |
Parkinsonism as a falling sickness.
Topics: Age Factors; Aged; Amantadine; Female; Gait; Humans; Levodopa; Male; Middle Aged; Movement Disorders | 1974 |
Effect of nalorphine and antiparkinsonian drugs on methadone-induced rigidity; relation to homovanillic acid content of nucleus caudatus.
Topics: Amantadine; Animals; Atropine; Body Temperature; Brain; Caudate Nucleus; Depression, Chemical; Dose- | 1972 |
Interactions of L-dopa and amantadine in patients with Parkinsonism.
Topics: Amantadine; Dihydroxyphenylalanine; Drug Interactions; Evaluation Studies as Topic; Female; Homovani | 1973 |
Hallervorden-Spatz syndrome.
Topics: Adult; Amantadine; Autopsy; Brain; Brain Diseases; Cerebral Cortex; Deferoxamine; Electroencephalogr | 1974 |