amantadine has been researched along with Morphine Dependence in 2 studies
amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source
Morphine Dependence: Strong dependence, both physiological and emotional, upon morphine.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Under conditions of morphine withdrawal, intraperitoneal injection of amantadine (10 or 20 mg/kg) decreased motor activity and promoted body weight loss in parallel with the development of mechanical allodynia, but had no effect on the total withdrawal score." | 3.91 | Comparative Assessment of the Effectiveness of Noncompetitive NMDA Receptor Antagonists Amantadine and Hemantane in Morphine Withdrawal Syndrome Model. ( Kolik, LG; Konstantinopolsky, MA, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kolik, LG | 1 |
| Konstantinopolsky, MA | 1 |
| Way, EL | 1 |
| Iwamoto, ET | 1 |
| Khanna, S | 1 |
| Ho, IK | 1 |
| Shen, F | 1 |
| Loh, HH | 1 |
2 other studies available for amantadine and Morphine Dependence
| Article | Year |
|---|---|
Comparative Assessment of the Effectiveness of Noncompetitive NMDA Receptor Antagonists Amantadine and Hemantane in Morphine Withdrawal Syndrome Model.
Topics: Adamantane; Amantadine; Animals; Gene Expression; Hyperalgesia; Injections, Intraperitoneal; Male; M | 2019 |
Precipitation of abstinence-like syndrome in morphine-dependent mice by pargyline.
Topics: Amantadine; Amphetamine; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Synergism | 1976 |