amantadine has been researched along with Liver Cirrhosis in 14 studies
amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source
Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The safety and long term effect of alpha interferon induction plus ribavirin with or without amantadine in the treatment of interferon non-responsive chronic hepatitis C was evaluated." | 9.10 | Effects of alpha interferon induction plus ribavirin with or without amantadine in the treatment of interferon non-responsive chronic hepatitis C: a randomised trial. ( Adinolfi, LE; Ruggiero, G; Tonziello, A; Utili, R, 2003) |
| "Amantadine has been proposed to improve response rates in addition to standard therapy with peginterferon alpha and ribavirin." | 6.75 | A randomized controlled trial of double versus triple therapy with amantadine for genotype 1 chronic hepatitis C in Latino patients. ( Chirino, RA; Chung, RT; Corey, KE; Dehesa-Violante, M; Gorospe, EC; Juarez, JA; Méndez-Navarro, J; Morán, S; Zheng, H, 2010) |
| "The safety and long term effect of alpha interferon induction plus ribavirin with or without amantadine in the treatment of interferon non-responsive chronic hepatitis C was evaluated." | 5.10 | Effects of alpha interferon induction plus ribavirin with or without amantadine in the treatment of interferon non-responsive chronic hepatitis C: a randomised trial. ( Adinolfi, LE; Ruggiero, G; Tonziello, A; Utili, R, 2003) |
| "At present the treatment of hepatitis C virus infection (HCV) has improved because of combined treatment with interferon (IFN) and ribavirin." | 3.71 | Hepatitis C: who should you treat and how? ( Rodés, J; Sánchez Tapias, JM, 2002) |
| "Amantadine has been proposed to improve response rates in addition to standard therapy with peginterferon alpha and ribavirin." | 2.75 | A randomized controlled trial of double versus triple therapy with amantadine for genotype 1 chronic hepatitis C in Latino patients. ( Chirino, RA; Chung, RT; Corey, KE; Dehesa-Violante, M; Gorospe, EC; Juarez, JA; Méndez-Navarro, J; Morán, S; Zheng, H, 2010) |
| "Despite improvements in the treatment of chronic hepatitis C virus (HCV) infection, nearly half of all patients do not respond to initial therapy." | 2.42 | Retreatment of patients who do not respond to initial therapy for chronic hepatitis C. ( Shiffman, ML, 2004) |
| "The objective of treatment for chronic hepatitis C is to prevent in the long term the complications and death that this disease may cause." | 1.36 | Chronic hepatitis C treatment in näive patients. ( Daruich, J, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 9 (64.29) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khokhar, N | 1 |
| Qureshi, MO | 1 |
| Niazi, TK | 1 |
| Nair, S | 1 |
| Lipscomb, J | 1 |
| Eason, J | 1 |
| Méndez-Navarro, J | 1 |
| Chirino, RA | 1 |
| Corey, KE | 1 |
| Gorospe, EC | 1 |
| Zheng, H | 1 |
| Morán, S | 1 |
| Juarez, JA | 1 |
| Chung, RT | 1 |
| Dehesa-Violante, M | 1 |
| Daruich, J | 1 |
| Gervais, A | 1 |
| Asselah, T | 1 |
| Adinolfi, LE | 1 |
| Utili, R | 1 |
| Tonziello, A | 1 |
| Ruggiero, G | 1 |
| Shiffman, ML | 1 |
| Pol, S | 1 |
| Fontaine, H | 1 |
| Vallet-Pichard, A | 1 |
| Sánchez Tapias, JM | 1 |
| Rodés, J | 1 |
| Koczorek, M | 1 |
| Morgan, MY | 1 |
| Schnack, H | 1 |
| Wewalka, F | 1 |
| Guttmann, G | 1 |
6 reviews available for amantadine and Liver Cirrhosis
| Article | Year |
|---|---|
[Chronic hepatitis C in HIV-HCV coinfected patients].
Topics: Adult; Age Factors; Amantadine; Antiretroviral Therapy, Highly Active; Antiviral Agents; Carcinoma, | 2002 |
Consensus conference. Treatment of hepatitis C.
Topics: Adult; Aged; Alcoholism; Amantadine; Antiviral Agents; Body Weight; Child; Drug Therapy, Combination | 2002 |
[Chronic hepatitis C: what to do if the first treatment failed?].
Topics: Amantadine; Animals; Antiviral Agents; Carcinoma, Hepatocellular; Drug Therapy, Combination; Ethanol | 2002 |
Retreatment of patients who do not respond to initial therapy for chronic hepatitis C.
Topics: Adjuvants, Immunologic; Alcoholism; Amantadine; Antiviral Agents; Black or African American; Clinica | 2004 |
[Treatments for hepatitis virus C infections].
Topics: Amantadine; Antiviral Agents; Carcinoma, Hepatocellular; Hepatitis C; Humans; Interferon-alpha; Live | 2001 |
The treatment of chronic hepatic encephalopathy.
Topics: Amantadine; Amino Acids, Branched-Chain; Anti-Bacterial Agents; Bromocriptine; Dietary Proteins; Hep | 1991 |
4 trials available for amantadine and Liver Cirrhosis
| Article | Year |
|---|---|
Efficacy of interferon based antiviral therapy for recurrent hepatitis C in patients who received steroid free immunosuppression for liver transplantation.
Topics: Amantadine; Antibodies, Monoclonal; Antilymphocyte Serum; Antiviral Agents; Disease Progression; Dru | 2008 |
A randomized controlled trial of double versus triple therapy with amantadine for genotype 1 chronic hepatitis C in Latino patients.
Topics: Adult; Amantadine; Antiviral Agents; Biopsy; Chi-Square Distribution; Drug Therapy, Combination; Fem | 2010 |
Effects of alpha interferon induction plus ribavirin with or without amantadine in the treatment of interferon non-responsive chronic hepatitis C: a randomised trial.
Topics: Adult; Alanine Transaminase; Amantadine; Antiviral Agents; Drug Administration Schedule; Drug Therap | 2003 |
Liver function during amantadine hydrochloride medication in compensated liver disease.
Topics: Alanine Transaminase; Alkaline Phosphatase; Amantadine; Aspartate Aminotransferases; Bilirubin; Bloo | 1969 |
4 other studies available for amantadine and Liver Cirrhosis
| Article | Year |
|---|---|
Treatment of decompensated cirrhosis secondary to hepatitis C with antiviral therapy.
Topics: Adult; Aged; Amantadine; Antiviral Agents; Drug Administration Schedule; Female; Follow-Up Studies; | 2013 |
Chronic hepatitis C treatment in näive patients.
Topics: Amantadine; Antiviral Agents; Drug Therapy, Combination; Genotype; Hepacivirus; Hepatitis C, Chronic | 2010 |
Hepatitis C: who should you treat and how?
Topics: Amantadine; Antiviral Agents; Decision Making; Decision Trees; Drug Therapy, Combination; Hepatitis | 2002 |
[Chronic liver diseases. The nihilism has gone].
Topics: Amantadine; Antioxidants; Antiviral Agents; Chronic Disease; Dipeptides; Drug Therapy, Combination; | 2001 |