Page last updated: 2024-10-22

amantadine and Lipidoses

amantadine has been researched along with Lipidoses in 4 studies

amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source

Lipidoses: Conditions characterized by abnormal lipid deposition due to disturbance in lipid metabolism, such as hereditary diseases involving lysosomal enzymes required for lipid breakdown. They are classified either by the enzyme defect or by the type of lipid involved.

Research Excerpts

ExcerptRelevanceReference
"Phospholipidosis is an adverse effect caused by numerous cationic amphiphilic drugs and can affect many cell types."1.36Predicting phospholipidosis using machine learning. ( Glen, RC; Lowe, R; Mitchell, JB, 2010)
"Chlorphentermine was used as reference compound."1.27Amantadine-induced lipidosis. A cytological and physicochemical study. ( Burmester, J; Hanpft, R; Kröplin, K; Lüllmann-Rauch, R; Patten, M, 1987)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lowe, R1
Glen, RC1
Mitchell, JB1
Zweije-Hofman, IL1
van der Zee, HJ1
van Nieuwenhuizen, O1
Hostetler, KY1
Matsuzawa, Y1
Burmester, J1
Hanpft, R1
Kröplin, K1
Lüllmann-Rauch, R1
Patten, M1

Trials

1 trial available for amantadine and Lipidoses

ArticleYear
Anti-parkinson drugs in the Batten-Spielmeyer-Vogt syndrome; a pilot trial.
    Clinical neurology and neurosurgery, 1982, Volume: 84, Issue:2

    Topics: Adolescent; Adult; Amantadine; Antiparkinson Agents; Benserazide; Drug Combinations; Humans; Levodop

1982

Other Studies

3 other studies available for amantadine and Lipidoses

ArticleYear
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Bio

2010
Studies on the mechanism of drug-induced lipidosis. Cationic amphiphilic drug inhibition of lysosomal phospholipases A and C.
    Biochemical pharmacology, 1981, May-15, Volume: 30, Issue:10

    Topics: Amantadine; Aniline Compounds; Animals; Chlorphentermine; Chlorpromazine; Heptanes; Imipramine; Lipi

1981
Amantadine-induced lipidosis. A cytological and physicochemical study.
    Toxicology, 1987, Volume: 44, Issue:1

    Topics: Amantadine; Animals; Cells, Cultured; Chlorphentermine; Inclusion Bodies; Kidney; Lipidoses; Liver;

1987