amantadine has been researched along with Leukemia in 4 studies
amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of the present study was to characterize the cytotoxic effects of the new semisynthetic cardenolide analog AMANTADIG (3β-[2-(1-amantadine)-1-on-ethylamine]-digitoxigenin), and the cardenolide digitoxin on leukemia and urological tumor cell lines." | 7.81 | The New Semisynthetic Cardenolide Analog 3β-[2-(1-Amantadine)-1-on-ethylamine]-digitoxigenin (AMANTADIG) Efficiently Suppresses Cell Growth in Human Leukemia and Urological Tumor Cell Lines. ( Ebert, N; Hertlein, H; Kreis, W; Müller-Uri, F; Nolte, E; Slany, R; Sobel, A; Taubert, H; Wach, S; Wullich, B, 2015) |
| " The aim of the present study was to characterize the cytotoxic effects of the new semisynthetic cardenolide analog AMANTADIG (3β-[2-(1-amantadine)-1-on-ethylamine]-digitoxigenin), and the cardenolide digitoxin on leukemia and urological tumor cell lines." | 3.81 | The New Semisynthetic Cardenolide Analog 3β-[2-(1-Amantadine)-1-on-ethylamine]-digitoxigenin (AMANTADIG) Efficiently Suppresses Cell Growth in Human Leukemia and Urological Tumor Cell Lines. ( Ebert, N; Hertlein, H; Kreis, W; Müller-Uri, F; Nolte, E; Slany, R; Sobel, A; Taubert, H; Wach, S; Wullich, B, 2015) |
| "The importance and significance of amantadine- or rimantadine-resistant influenza viruses in immunocompromised patients was studied in a population of adult bone marrow transplant (BMT) recipients and patients with leukemia prospectively cultured for respiratory viruses." | 3.70 | Common emergence of amantadine- and rimantadine-resistant influenza A viruses in symptomatic immunocompromised adults. ( Atmar, RL; Champlin, RE; Cox, NJ; Englund, JA; Kantarjian, H; Klimov, AI; Regnery, H; Tarrand, J; Whimbey, E; Wyde, PR; Yousuf, H, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nolte, E | 1 |
| Sobel, A | 1 |
| Wach, S | 1 |
| Hertlein, H | 1 |
| Ebert, N | 1 |
| Müller-Uri, F | 1 |
| Slany, R | 1 |
| Taubert, H | 1 |
| Wullich, B | 1 |
| Kreis, W | 1 |
| Englund, JA | 1 |
| Champlin, RE | 1 |
| Wyde, PR | 1 |
| Kantarjian, H | 1 |
| Atmar, RL | 1 |
| Tarrand, J | 1 |
| Yousuf, H | 1 |
| Regnery, H | 1 |
| Klimov, AI | 1 |
| Cox, NJ | 1 |
| Whimbey, E | 1 |
| Mathé, G | 1 |
| Schwarzenberg, L | 1 |
| Amiel, JL | 1 |
| Pouillart, P | 1 |
| Hayat, M | 1 |
| de Vassal, F | 1 |
| Rosenfeld, C | 1 |
| Jasmin, C | 1 |
| Oker-Blom, N | 1 |
| Andersen, L | 1 |
1 trial available for amantadine and Leukemia
| Article | Year |
|---|---|
New experimental and clinical data on leukaemia immunotherapy.
Topics: Adolescent; Adult; Amantadine; Animals; Bacterial Vaccines; BCG Vaccine; Cell Line; Central Nervous | 1975 |
3 other studies available for amantadine and Leukemia
| Article | Year |
|---|---|
The New Semisynthetic Cardenolide Analog 3β-[2-(1-Amantadine)-1-on-ethylamine]-digitoxigenin (AMANTADIG) Efficiently Suppresses Cell Growth in Human Leukemia and Urological Tumor Cell Lines.
Topics: Amantadine; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Digitoxigeni | 2015 |
Common emergence of amantadine- and rimantadine-resistant influenza A viruses in symptomatic immunocompromised adults.
Topics: Adult; Amantadine; Antiviral Agents; Bone Marrow Transplantation; Drug Resistance, Microbial; Humans | 1998 |
Inhibition of Rous sarcoma virus and chicken leukosis viruses by 1-adamantanamine hydrochloride.
Topics: Amantadine; Animals; Avian Leukosis Virus; Avian Sarcoma Viruses; Chickens; Leukemia | 1967 |