amantadine has been researched along with Infections, Respiratory in 51 studies
amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amantadine-HC1, an antiviral drug clinically effective against most strains of influenza A virus, was evaluated in a double-blind trial in 153 children with cystic fibrosis during the initial appearance of influenza A/England/42 virus in the New England area." | 9.04 | Evaluation of the safety of amantadine-HC1 and the role of respiratory viral infections in children with cystic fibrosis. ( Khaw, KT; Oxman, MN; Shwachman, H; Wright, PF, 1976) |
| "Amantadine-HC1, an antiviral drug clinically effective against most strains of influenza A virus, was evaluated in a double-blind trial in 153 children with cystic fibrosis during the initial appearance of influenza A/England/42 virus in the New England area." | 5.04 | Evaluation of the safety of amantadine-HC1 and the role of respiratory viral infections in children with cystic fibrosis. ( Khaw, KT; Oxman, MN; Shwachman, H; Wright, PF, 1976) |
| " This allowed a total dosage not much less than might have been given by other routes, but with the advantage that it was evenly deposited over the surface of the infected respiratory tract beginning within seconds of the start of treatment and reached higher concentration in nasal secretions than in serum." | 3.76 | Chemotherapy of respiratory viruses. ( Gilbert, BE; Knight, V, 1986) |
| "(table: see text) For influenza A virus infections, both oral amantadine and rimantadine are effective when used for seasonal prophylaxis and for prophylaxis in institutional populations." | 3.75 | Clinical applications of antiviral agents for chemophrophylaxis and therapy of respiratory viral infections. ( Hayden, FG, 1985) |
| " These questions concern appropriate routes of administration for antiviral compounds, optimal dosage regimens, risks of long-term prophylaxis, and the emergence of resistant organisms." | 2.66 | Antiviral chemotherapy and chemoprophylaxis. ( Dolin, R, 1985) |
| "Epidemic influenza occurred only in the two groups of conscripts: the incidence of serologically verified influenza was 66% and 83% in the groups that received placebo and 43% and 51% in the groups that received amantadine, giving protection rates of 36% (P = 0." | 2.65 | Evaluation of amantadine in the prophylaxis of influenza A (H1N1) virus infection: a controlled field trial among young adults and high-risk patients. ( Hellström, PE; Penttinen, K; Pettersson, RF; Pyhälä, R; Tokola, O; Vartio, T; Visakorpi, R, 1980) |
| " Plasma half-life averaged 68." | 2.65 | Amantadine hydrochloride pharmacokinetics in patients with impaired renal function. ( Daugirdas, JT; Gandhi, VC; Hano, JE; Ing, TS; Soung, LS; Wu, MJ, 1982) |
| "The amantadine-treated patients experienced a significantly more rapid resolution of clinical signs and symptoms when compared with placebo-treated patients." | 2.65 | Therapeutic effects of aerosolized amantadine in naturally acquired infection due to influenza A virus. ( Douglas, RG; Hall, WJ; Hayden, FG, 1980) |
| " Gross and subtle side effects of amantadine observed in this study on currently recommended dosage are higher than previously reported, which may be an important factor in consideration of mass prophylaxis." | 2.65 | A prospective double-blind study of side effects associated with the administration of amantadine for influenza A virus prophylaxis. ( Bryson, YJ; Monahan, C; Pollack, M; Shields, WD, 1980) |
| "Respiratory viruses (influenza, parainfluenza, respiratory syncytial virus, coronavirus, human metapneumovirus, and rhinovirus) represent the most common causes of respiratory viral infections in immunocompromised patients." | 2.55 | Antiviral therapy for respiratory viral infections in immunocompromised patients. ( Ariza-Heredia, EJ; Chemaly, RF; Shahani, L, 2017) |
| "In upper respiratory tract infections, which are frequent and fortunately not severe, their deficiency is not a problem." | 2.40 | [Drugs active against respiratory viruses]. ( Freymuth, F; Vabret, A, 1997) |
| "However, comparing rhinovirus and influenza, there is no doubt that influenza viruses produce more severe symptoms." | 2.39 | Viral respiratory infections in the community: epidemiology, agents, and interventions. ( Monto, AS, 1995) |
| " Intranasal application of interferon is effective in interrupting the spread of rhinovirus colds in families, but chronic use is limited by nasal toxicity." | 2.37 | Antiviral chemotherapy and prophylaxis of viral respiratory disease. ( Hayden, FG; Sperber, SJ, 1987) |
| "The International Society for Influenza and other Respiratory Virus Diseases (isirv) held its 4th Antiviral Group Conference at the University of Texas on 2-4 June, 2015." | 1.43 | Meeting report: 4th ISIRV antiviral group conference: Novel antiviral therapies for influenza and other respiratory viruses. ( Fry, AM; McKimm-Breschkin, JL, 2016) |
| " We studied the severity of illness due to influenza among adults residing in a center for the developmentally disabled and assessed adverse reactions to amantadine and oseltamivir prophylaxis." | 1.32 | Adverse effects of amantadine and oseltamivir used during respiratory outbreaks in a center for developmentally disabled adults. ( Benjamin, JH; Gardner, C; Green, K; Lee, W; Loeb, M; McArthur, M; McGeer, AJ; Simor, AE, 2004) |
| "This combination warrants testing in human influenza." | 1.29 | Combination antiviral therapy for respiratory virus infections. ( Hayden, FG, 1996) |
| "Amantadine is an antiviral agent that is also used in the treatment of parkinsonism and neuroleptic-induced extrapyramidal symptoms." | 1.28 | Acute psychosis after amantadine overdose. ( Bessen, HA; Snoey, ER, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 44 (86.27) | 18.7374 |
| 1990's | 4 (7.84) | 18.2507 |
| 2000's | 1 (1.96) | 29.6817 |
| 2010's | 2 (3.92) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McKimm-Breschkin, JL | 1 |
| Fry, AM | 1 |
| Shahani, L | 1 |
| Ariza-Heredia, EJ | 1 |
| Chemaly, RF | 1 |
| McGeer, AJ | 1 |
| Lee, W | 1 |
| Loeb, M | 1 |
| Simor, AE | 1 |
| McArthur, M | 1 |
| Green, K | 1 |
| Benjamin, JH | 1 |
| Gardner, C | 1 |
| Nicholson, KG | 1 |
| Tovo, PA | 1 |
| Richmond, S | 1 |
| Longson, M | 1 |
| White, DO | 1 |
| Togo, Y | 2 |
| Flenley, DC | 1 |
| Taros, LIu | 1 |
| Malysheva, AM | 1 |
| Pettersson, RF | 1 |
| Hellström, PE | 1 |
| Penttinen, K | 1 |
| Pyhälä, R | 1 |
| Tokola, O | 1 |
| Vartio, T | 1 |
| Visakorpi, R | 1 |
| Wu, MJ | 1 |
| Ing, TS | 1 |
| Soung, LS | 1 |
| Daugirdas, JT | 1 |
| Hano, JE | 1 |
| Gandhi, VC | 1 |
| Hayden, FG | 4 |
| Hall, WJ | 1 |
| Douglas, RG | 1 |
| Bryson, YJ | 1 |
| Monahan, C | 1 |
| Pollack, M | 1 |
| Shields, WD | 1 |
| Monto, AS | 1 |
| Freymuth, F | 1 |
| Vabret, A | 1 |
| Diana, GD | 1 |
| Pancic, F | 1 |
| Kundu, BC | 1 |
| Jackson, GG | 1 |
| Wright, PF | 1 |
| Khaw, KT | 1 |
| Oxman, MN | 1 |
| Shwachman, H | 1 |
| Waldman, RH | 1 |
| Lee, JD | 1 |
| Snoey, ER | 1 |
| Bessen, HA | 1 |
| Knight, V | 1 |
| Gilbert, BE | 1 |
| Cunningham, AL | 1 |
| Sperber, SJ | 1 |
| Johnson, DC | 1 |
| Steele, RW | 1 |
| Cate, TR | 1 |
| Graman, PS | 1 |
| Hall, CB | 1 |
| Dolin, R | 1 |
| Cates, KL | 1 |
| Chonmaitree, T | 1 |
| Truant, AL | 1 |
| Vivell, O | 1 |
| Halonen, P | 1 |
| Mujunen, R | 1 |
| Mäntyjärvi, R | 1 |
| Bunn, PA | 1 |
| Kaji, M | 1 |
| Goetz, O | 1 |
| Schirmböck, J | 1 |
| Rubenstein, D | 1 |
| Tyrrell, DA | 2 |
| Inglot, AD | 1 |
| Juel-Jensen, BE | 1 |
| Zykov, MP | 1 |
| Smorodintsev, AA | 1 |
| Alexandrova, GI | 1 |
| Zlydnikov, DM | 2 |
| Golubev, DB | 1 |
| Shadrin, AS | 1 |
| Merrigan, TC | 1 |
| Wegmann, T | 2 |
| Finklea, JF | 1 |
| Hennessy, AV | 1 |
| Davenport, FM | 1 |
| Matkovskiĭ, VS | 1 |
| Kazantsev, AP | 1 |
| Starshov, PD | 1 |
| Antonov, VS | 1 |
| Máté, J | 1 |
| Simon, M | 1 |
| Juvancz, I | 1 |
| Takátsy, G | 1 |
| Hollós, I | 1 |
| Farkas, E | 1 |
19 reviews available for amantadine and Infections, Respiratory
| Article | Year |
|---|---|
Antiviral therapy for respiratory viral infections in immunocompromised patients.
Topics: Acids, Carbocyclic; Amantadine; Antiviral Agents; Coronavirus Infections; Cyclopentanes; Guanidines; | 2017 |
Antiviral therapy. Respiratory infections, genital herpes, and herpetic keratitis.
Topics: Acyclovir; Adult; Amantadine; Antiviral Agents; Child; Female; Herpes Genitalis; Humans; Idoxuridine | 1984 |
Antiviral chemotherapy.
Topics: Acyclovir; Amantadine; Animals; Antiviral Agents; Bromodeoxyuridine; Female; Hepatitis B; Herpes Gen | 1984 |
[Future of antifungal and antiviral agents. 2. Antiviral agents. b. Present status of chemotherapy of viral infections of the respiratory tract].
Topics: Amantadine; Antiviral Agents; Humans; Interferons; Respiratory Tract Infections; Ribavirin; Rimantad | 1984 |
New drugs in respiratory disorders: II.
Topics: Adult; Aged; Amantadine; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Cephalosporins; | 1983 |
Viral respiratory infections in the community: epidemiology, agents, and interventions.
Topics: Adolescent; Adult; Age Factors; Aged; Amantadine; Antiviral Agents; Child; Child, Preschool; Humans; | 1995 |
[Drugs active against respiratory viruses].
Topics: Amantadine; Antiviral Agents; Orthomyxoviridae; Respiratory Syncytial Viruses; Respiratory Tract Inf | 1997 |
Chemotherapy of virus diseases.
Topics: Amantadine; Antiviral Agents; Cytarabine; Drug Evaluation; Herpesviridae Infections; Humans; Idoxuri | 1976 |
Clinical applications of antiviral agents for chemophrophylaxis and therapy of respiratory viral infections.
Topics: Adult; Amantadine; Antiviral Agents; Child; Child, Preschool; Clinical Trials as Topic; Humans; Infl | 1985 |
Chemotherapy of respiratory viruses.
Topics: Acyclovir; Adult; Amantadine; Animals; Antiviral Agents; Benzimidazoles; Child; Clinical Trials as T | 1986 |
Antiviral chemotherapy and prophylaxis of viral respiratory disease.
Topics: Amantadine; Animals; Antiviral Agents; Humans; Interferons; Respiratory Tract Infections; Ribavirin; | 1987 |
Antiviral agents for respiratory infections.
Topics: Amantadine; Antiviral Agents; Child; Humans; Interferons; Respiratory Tract Infections; Ribavirin; R | 1988 |
Nosocomial viral respiratory infections.
Topics: Aged; Amantadine; Child; Child, Preschool; Cross Infection; Disease Outbreaks; Humans; Infant; Influ | 1989 |
Clinical considerations in the diagnosis of viral respiratory infections.
Topics: Amantadine; Antibodies, Monoclonal; Antigens, Viral; Cross Infection; Humans; Influenza A virus; Inf | 1986 |
What's new in the treatment of viral respiratory infections in children. Part II.
Topics: Amantadine; Child; Child, Preschool; Humans; Infant; Respiratory Tract Infections; Ribavirin; Ribonu | 1985 |
Advances in the treatment of virus diseases.
Topics: Amantadine; Anti-Bacterial Agents; Antiviral Agents; Binding Sites; Gastroenteritis; Herpesviridae I | 1971 |
Antiviral drugs in human therapy.
Topics: Amantadine; Anti-Inflammatory Agents; Antimetabolites; Antiviral Agents; Chemical Phenomena; Chemist | 1973 |
The present and future of specific prophylaxis of influenza and other acute viral respiratory diseases.
Topics: Acute Disease; Adult; Amantadine; Animals; Antigens, Viral; Antiviral Agents; Bridged-Ring Compounds | 1974 |
The possible chemotherapy of respiratory virus diseases.
Topics: Adult; Amantadine; Animals; Antiviral Agents; Ascorbic Acid; Child; Cytopathogenic Effect, Viral; DN | 1969 |
13 trials available for amantadine and Infections, Respiratory
| Article | Year |
|---|---|
Evaluation of amantadine in the prophylaxis of influenza A (H1N1) virus infection: a controlled field trial among young adults and high-risk patients.
Topics: Adult; Aged; Aging; Amantadine; Antibodies, Viral; Clinical Trials as Topic; Disease Outbreaks; Doub | 1980 |
Amantadine hydrochloride pharmacokinetics in patients with impaired renal function.
Topics: Adult; Amantadine; Antiviral Agents; Clinical Trials as Topic; Creatinine; Drug Evaluation; Humans; | 1982 |
Therapeutic effects of aerosolized amantadine in naturally acquired infection due to influenza A virus.
Topics: Adult; Aerosols; Amantadine; Double-Blind Method; Female; Humans; Influenza A virus; Influenza, Huma | 1980 |
A prospective double-blind study of side effects associated with the administration of amantadine for influenza A virus prophylaxis.
Topics: Adolescent; Adult; Amantadine; Central Nervous System; Dizziness; Dose-Response Relationship, Drug; | 1980 |
A perspective from controlled investigations of chemotherapy for viral respiratory infections.
Topics: Amantadine; Animals; Antiviral Agents; Caffeic Acids; Clinical Trials as Topic; Ferrets; Humans; In | 1976 |
Evaluation of the safety of amantadine-HC1 and the role of respiratory viral infections in children with cystic fibrosis.
Topics: Adolescent; Adult; Amantadine; Child; Child, Preschool; Clinical Trials as Topic; Cystic Fibrosis; F | 1976 |
Clinical applications of antiviral agents for chemophrophylaxis and therapy of respiratory viral infections.
Topics: Adult; Amantadine; Antiviral Agents; Child; Child, Preschool; Clinical Trials as Topic; Humans; Infl | 1985 |
Chemotherapy of respiratory viruses.
Topics: Acyclovir; Adult; Amantadine; Animals; Antiviral Agents; Benzimidazoles; Child; Clinical Trials as T | 1986 |
Antiviral chemotherapy and chemoprophylaxis.
Topics: Acyclovir; Adult; Aged; Amantadine; Antiviral Agents; Chickenpox; Clinical Trials as Topic; Cytomega | 1985 |
[On the preventive effect of amantadine hydrochloride in influenza and other respiratory viral infections].
Topics: Adenoviridae Infections; Adult; Amantadine; Antiviral Agents; Clinical Trials as Topic; Humans; Infl | 1965 |
[Epidemiological studies of common cold diseases. Diagnosis and therapy].
Topics: Adenoviridae; Amantadine; Complement Fixation Tests; Germany, West; Humans; Male; Military Medicine; | 1967 |
A field trial of amantadine prophylaxis in naturally-occurring acute respiratory illness.
Topics: Adolescent; Adult; Amantadine; Antiviral Agents; Child; Clinical Trials as Topic; Complement Fixatio | 1967 |
Prophylactic use of amantadine during Hong Kong influenza epidemic.
Topics: Adolescent; Adult; Amantadine; Animals; Antibodies; Antibody Formation; Capsules; Chickens; Disease | 1970 |
21 other studies available for amantadine and Infections, Respiratory
| Article | Year |
|---|---|
Meeting report: 4th ISIRV antiviral group conference: Novel antiviral therapies for influenza and other respiratory viruses.
Topics: Amantadine; Antibody-Dependent Enhancement; Antiviral Agents; Coronavirus Infections; Drug Resistanc | 2016 |
Adverse effects of amantadine and oseltamivir used during respiratory outbreaks in a center for developmentally disabled adults.
Topics: Acetamides; Adult; Aged; Amantadine; Antiviral Agents; Child; Comorbidity; Developmental Disabilitie | 2004 |
[Antiviral therapy today].
Topics: Amantadine; Antiviral Agents; Cytarabine; Humans; Immunoglobulin A; Inosine Pranobex; Interferons; L | 1980 |
Recent advances in antiviral agents.
Topics: Acyclovir; Amantadine; Antiviral Agents; Carrier State; Hepatitis B; Herpesviridae Infections; Human | 1982 |
[Evaluation of the effectiveness of amantadine in various respiratory infections based on the results of a serological study].
Topics: Amantadine; Antibodies, Bacterial; Antibodies, Viral; Drug Evaluation; Humans; Mycoplasma pneumoniae | 1982 |
Combination antiviral therapy for respiratory virus infections.
Topics: Amantadine; Animals; Antiviral Agents; Common Cold; Drug Therapy, Combination; Humans; Influenza, Hu | 1996 |
[Chemotherapy of viral respiratory tract infections].
Topics: Amantadine; Humans; Interferons; Respiratory Tract Infections; Virus Diseases | 1977 |
Respiratory crisis in Parkinson's disease.
Topics: Aged; Amantadine; Crisis Intervention; Humans; Parkinson Disease; Respiratory Tract Infections | 1978 |
Management of common viral infections.
Topics: Amantadine; Coloring Agents; Gastroenteritis; Humans; Idoxuridine; Methisazone; Respiratory Tract In | 1977 |
Acute psychosis after amantadine overdose.
Topics: Adult; Amantadine; Diagnosis, Differential; Diphenhydramine; Drug Synergism; Female; Hallucinations; | 1990 |
New modalities in antiviral therapy.
Topics: Acyclovir; Amantadine; Antiviral Agents; Common Cold; Herpesviridae Infections; Humans; Interferons; | 1986 |
Antiviral drugs for common respiratory diseases. What's here, what's to come.
Topics: Adult; Aged; Amantadine; Antiviral Agents; Child; Female; Humans; Infant; Infant, Newborn; Influenza | 1988 |
Prevention of severe lower respiratory tract infections.
Topics: Amantadine; Disease Outbreaks; Humans; Influenza, Human; Nursing Homes; Respiratory Tract Infections | 1989 |
[Treatment of virus diseases].
Topics: Amantadine; Analgesics; Animals; Anti-Bacterial Agents; Antiviral Agents; Biguanides; gamma-Globulin | 1970 |
Pneumonia in the older patient.
Topics: Aged; Aging; Amantadine; Anti-Bacterial Agents; Cephalosporins; DNA Nucleotidyltransferases; Gentami | 1968 |
[Study on chemotherapy of virus infections of the respiratory organs].
Topics: Adenoviridae Infections; Amantadine; Animals; Antiviral Agents; Guanidines; Humans; Influenza, Human | 1967 |
Virus diseases.
Topics: Amantadine; Chickenpox; Cytarabine; Cytomegalovirus; DNA Viruses; Eye Diseases; Female; Genital Dise | 1974 |
Editorial: Interferon inducers revisited.
Topics: Amantadine; Humans; Influenza, Human; Interferon Inducers; Interferons; Respiratory Tract Infections | 1974 |
[Therapy of acute respiratory tract infections].
Topics: Acute Disease; Amantadine; Ampicillin; Humans; Interferons; Penicillin G; Respiratory Tract Infectio | 1972 |
[Therapy of acute respiratory tract infections].
Topics: Acute Disease; Amantadine; Ampicillin; Humans; Immunotherapy; Interferons; Respiratory Tract Infecti | 1972 |
[Preventive and therapeutic action of amantadine in acute respiratory diseases].
Topics: Amantadine; Military Medicine; Respiratory Tract Infections; USSR | 1970 |