amantadine has been researched along with Hepatitis B, Chronic in 4 studies
amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source
Hepatitis B, Chronic: INFLAMMATION of the LIVER in humans caused by HEPATITIS B VIRUS lasting six months or more. It is primarily transmitted by parenteral exposure, such as transfusion of contaminated blood or blood products, but can also be transmitted via sexual or intimate personal contact.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Combination therapy with Interferon-α and ribavirin remains the backbone treatment for chronic hepatitis C; the addition of serine protease inhibitors improves the treatment outcome of patients infected with hepatitis C virus genotype 1." | 4.87 | Antiviral drugs for viruses other than human immunodeficiency virus. ( Razonable, RR, 2011) |
| "The study population consisted of 53 HBsAg-negative patients with chronic hepatitis C treated with IFN/ribavirin or IFN/ribavirin/amantadine." | 3.73 | Analysis of HCV co-infection with occult hepatitis B virus in patients undergoing IFN therapy. ( Chemin, I; Guillaud, O; Khattab, E; Mrani, S; Trepo, C; Vieux, C; Vuillermoz, I; Zoulim, F, 2005) |
| "Treatment of patients with chronic hepatitis B (CHB) with nucleos(t)ide analogues (NAs) suppresses hepatitis B virus (HBV) DNA production but does not affect the synthesis of the RNA pregenome or HBV messenger RNA." | 2.82 | Hepatitis B Virus Pregenomic RNA Is Present in Virions in Plasma and Is Associated With a Response to Pegylated Interferon Alfa-2a and Nucleos(t)ide Analogues. ( Jansen, L; Kootstra, NA; Reesink, HW; Takkenberg, RB; van Dort, KA; Zaaijer, HL, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jansen, L | 1 |
| Kootstra, NA | 1 |
| van Dort, KA | 1 |
| Takkenberg, RB | 1 |
| Reesink, HW | 1 |
| Zaaijer, HL | 1 |
| Razonable, RR | 1 |
| Khattab, E | 1 |
| Chemin, I | 1 |
| Vuillermoz, I | 1 |
| Vieux, C | 1 |
| Mrani, S | 1 |
| Guillaud, O | 1 |
| Trepo, C | 1 |
| Zoulim, F | 1 |
| Friedrich-Rust, M | 1 |
| Forestier, N | 1 |
| Zeuzem, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Predictive Value of HBV pgRNA on Long-term Outcomes in Hepatitis B Patients Treated With Antiviral Therapy[NCT05965388] | 5,000 participants (Anticipated) | Observational | 2023-12-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for amantadine and Hepatitis B, Chronic
| Article | Year |
|---|---|
Antiviral drugs for viruses other than human immunodeficiency virus.
Topics: Acyclovir; Adenine; Amantadine; Antiviral Agents; Comorbidity; Drug Therapy, Combination; Foscarnet; | 2011 |
1 trial available for amantadine and Hepatitis B, Chronic
| Article | Year |
|---|---|
Hepatitis B Virus Pregenomic RNA Is Present in Virions in Plasma and Is Associated With a Response to Pegylated Interferon Alfa-2a and Nucleos(t)ide Analogues.
Topics: Adenine; Adult; Amantadine; Antiviral Agents; Biomarkers; DNA, Viral; Drug Therapy, Combination; Fem | 2016 |
2 other studies available for amantadine and Hepatitis B, Chronic
| Article | Year |
|---|---|
Analysis of HCV co-infection with occult hepatitis B virus in patients undergoing IFN therapy.
Topics: Adult; Amantadine; Amino Acid Sequence; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female | 2005 |
[Perspectives in hepatology in the next 2-3 years: what will be clinically relevant? Viral hepatitis].
Topics: Amantadine; Antiviral Agents; Genotype; Hepatitis B, Chronic; Hepatitis C, Chronic; Hepatovirus; Hum | 2005 |