Page last updated: 2024-10-22

amantadine and Hallucinations

amantadine has been researched along with Hallucinations in 26 studies

amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source

Hallucinations: Subjectively experienced sensations in the absence of an appropriate stimulus, but which are regarded by the individual as real. They may be of organic origin or associated with MENTAL DISORDERS.

Research Excerpts

ExcerptRelevanceReference
"Amantadine is an N-methyl-d-aspartate receptor agonist with secondary dopaminergic activity that is used to treat Parkinson's disease-related dyskinesia and to treat fatigue in multiple sclerosis."8.31Amantadine toxicity causing visual hallucinations. ( Barbara, JM; Pace, A, 2023)
"In 13 elderly patients, 12 of whom had Parkinson's disease, visual hallucinations and delirium developed as a side effect of amantadine hydrochloride (Symmetrel) therapy."7.65Visual hallucinations and delirium during treatment with amantadine (Symmetrel). ( Postma, JU; Van Tilburg, W, 1975)
"Amantadine hydrochloride is a commonly prescribed drug with a narrow therapeutic-to-toxic range."5.28Amantadine toxicity presenting with complex ventricular ectopy and hallucinations. ( Hughes, B; Pimentel, L, 1991)
"Amantadine is an N-methyl-d-aspartate receptor agonist with secondary dopaminergic activity that is used to treat Parkinson's disease-related dyskinesia and to treat fatigue in multiple sclerosis."4.31Amantadine toxicity causing visual hallucinations. ( Barbara, JM; Pace, A, 2023)
"In 13 elderly patients, 12 of whom had Parkinson's disease, visual hallucinations and delirium developed as a side effect of amantadine hydrochloride (Symmetrel) therapy."3.65Visual hallucinations and delirium during treatment with amantadine (Symmetrel). ( Postma, JU; Van Tilburg, W, 1975)
"Amantadine was reduced to 50mg daily for 4 days and then discontinued."2.72Amantadine Associated Myoclonus: Case Report and Review of the Literature. ( Lee, AJ; Poon, LH; Vuong, M; Zuzuarregui, JR, 2021)
"To investigate the association of illusions/hallucinations and plasma CRP levels in PD patients without symptomatic infections."1.40Subclinical elevation of plasma C-reactive protein and illusions/hallucinations in subjects with Parkinson's disease: case-control study. ( Hayashi, R; Kohsaka, M; Oeda, T; Sawada, H; Sudoh, S; Sugiyama, H; Tomita, S; Umemura, A; Yamamoto, K, 2014)
"We describe an artist who depicted her visual hallucinations experienced in the course of Parkinson's disease."1.32An artist's view of drug-induced hallucinosis. ( Ebersbach, G, 2003)
" This long range study demonstrates, through multiple varied dosing schedules, a trade off between the benefits and side effects of dopaminergic therapy, with implications for a larger brain injury population."1.30Effects of dopaminergic combination therapy for frontal lobe dysfunction in traumatic brain injury rehabilitation. ( Burke, DT; Calvanio, R; Fitzpatrick, M; Karli, DC; Kim, HJ; Lepak, P; Macneil, M; Pesez, K; Temple, D, 1999)
"Amantadine hydrochloride is a commonly prescribed drug with a narrow therapeutic-to-toxic range."1.28Amantadine toxicity presenting with complex ventricular ectopy and hallucinations. ( Hughes, B; Pimentel, L, 1991)
"Amantadine is an antiviral agent that is also used in the treatment of parkinsonism and neuroleptic-induced extrapyramidal symptoms."1.28Acute psychosis after amantadine overdose. ( Bessen, HA; Snoey, ER, 1990)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199010 (38.46)18.7374
1990's5 (19.23)18.2507
2000's6 (23.08)29.6817
2010's3 (11.54)24.3611
2020's2 (7.69)2.80

Authors

AuthorsStudies
Barbara, JM1
Pace, A1
Pajo, AT1
Espiritu, AI1
Jamora, RDG1
Poon, LH1
Lee, AJ1
Vuong, M1
Zuzuarregui, JR1
Sawada, H1
Oeda, T1
Umemura, A1
Tomita, S1
Hayashi, R1
Kohsaka, M1
Yamamoto, K1
Sudoh, S1
Sugiyama, H1
Nishikawa, N1
Nagai, M1
Moritoyo, T1
Yabe, H1
Nomoto, M1
Michalski, LS1
Hantsch Bardsley, C1
Holt, DR1
Milner, JE1
Hou, SH1
Gondim, Fde A1
Costa, HA1
Taunay, TC1
de Oliveira, GR1
Ferreira, JM1
Rola, FH1
Ebersbach, G1
Kitagawa, M1
Tashiro, K1
Benbir, G1
Ozekmekçi, S1
Cinar, M1
Beskardes, F1
Apaydin, H1
Erginöz, E1
Visanji, NP1
Gomez-Ramirez, J1
Johnston, TH1
Pires, D1
Voon, V1
Brotchie, JM1
Fox, SH1
Ideshita, H1
Morita, H1
Yoshinaga, J1
Sasaki, T1
Hikiji, A1
Dike, GL1
Karli, DC1
Burke, DT1
Kim, HJ1
Calvanio, R1
Fitzpatrick, M1
Temple, D1
Macneil, M1
Pesez, K1
Lepak, P1
Postma, JU1
Van Tilburg, W1
Strong, DK1
Eisenstat, DD1
Bryson, SM1
Sitar, DS1
Arbus, GS1
Pimentel, L1
Hughes, B1
Snoey, ER1
Bessen, HA1
Gold, N1
Penders, C1
Forssman, B1
Kihlstrand, S1
Larsson, LE1
Campbell, AM1
Williams, MJ1
Reveno, WS2
Bauer, RB2
Rosenbaum, H2
Harper, RW1
Knothe, BU1
Holmsen, R1

Reviews

2 reviews available for amantadine and Hallucinations

ArticleYear
Efficacy and safety of extended-release amantadine in levodopa-induced dyskinesias: a meta-analysis.
    Neurodegenerative disease management, 2019, Volume: 9, Issue:4

    Topics: Accidental Falls; Aged; Aged, 80 and over; Amantadine; Antiparkinson Agents; Bias; Constipation; Del

2019
Amantadine Associated Myoclonus: Case Report and Review of the Literature.
    Journal of pharmacy practice, 2021, Volume: 34, Issue:5

    Topics: Aged, 80 and over; Amantadine; Hallucinations; Humans; Levodopa; Male; Myoclonus; Parkinson Disease

2021

Trials

2 trials available for amantadine and Hallucinations

ArticleYear
Amantadine therapy in parkinsonism.
    Acta neurologica Scandinavica, 1972, Volume: 48, Issue:1

    Topics: Age Factors; Aged; Amantadine; Clinical Trials as Topic; Edema; Electrocardiography; Female; Follow-

1972
Trial of amantadine in Parkinson's disease.
    The British journal of clinical practice, 1972, Volume: 26, Issue:1

    Topics: Adult; Aged; Amantadine; Clinical Trials as Topic; Constipation; Female; Hallucinations; Handwriting

1972

Other Studies

22 other studies available for amantadine and Hallucinations

ArticleYear
Amantadine toxicity causing visual hallucinations.
    Practical neurology, 2023, Volume: 23, Issue:5

    Topics: Amantadine; Antiparkinson Agents; Female; Hallucinations; Humans; Levodopa; Multiple Sclerosis

2023
Subclinical elevation of plasma C-reactive protein and illusions/hallucinations in subjects with Parkinson's disease: case-control study.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Amantadine; C-Reactive Protein; Case-Control Studies; Cross-Sectional Studies; Delusions; Dopamine A

2014
Plasma amantadine concentrations in patients with Parkinson's disease.
    Parkinsonism & related disorders, 2009, Volume: 15, Issue:5

    Topics: Adult; Aged; Amantadine; Antiparkinson Agents; Creatinine; Delirium; Female; Hallucinations; Humans;

2009
Altered mental status in a transplant patient. Amantadine toxicity.
    Kidney international, 2009, Volume: 75, Issue:2

    Topics: Adult; Amantadine; Confusion; Diabetes Complications; Diabetes Mellitus, Type 1; Female; Hallucinati

2009
Transient amantadine-induced musical hallucinations in a patient with Parkinson's disease.
    Movement disorders : official journal of the Movement Disorder Society, 2010, Jul-30, Volume: 25, Issue:10

    Topics: Aged; Amantadine; Antiparkinson Agents; Female; Hallucinations; Humans; Music; Parkinson Disease

2010
An artist's view of drug-induced hallucinosis.
    Movement disorders : official journal of the Movement Disorder Society, 2003, Volume: 18, Issue:7

    Topics: Amantadine; Antiparkinson Agents; Dose-Response Relationship, Drug; Drug Therapy, Combination; Femal

2003
Low-dose levodopa therapy in Japanese patients with Parkinson's disease: a retrospective study.
    Internal medicine (Tokyo, Japan), 2005, Volume: 44, Issue:9

    Topics: Aged; Amantadine; Antiparkinson Agents; Dopamine Agonists; Dyskinesia, Drug-Induced; Hallucinations;

2005
Features associated with the development of hallucinations in Parkinson's disease.
    Acta neurologica Scandinavica, 2006, Volume: 114, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Amantadine; Antiparkinson Agents; Brain; Cholinergic Antagonists; Do

2006
Pharmacological characterization of psychosis-like behavior in the MPTP-lesioned nonhuman primate model of Parkinson's disease.
    Movement disorders : official journal of the Movement Disorder Society, 2006, Volume: 21, Issue:11

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amantadine; Animals; Antiparkinson Agents; Apomorphine

2006
[A study on mental symptoms developing during the treatment of Parkinson's disease (author's transl)].
    No to shinkei = Brain and nerve, 1980, Volume: 32, Issue:9

    Topics: Aged; Amantadine; Delusions; Drug Therapy, Combination; Female; Hallucinations; Humans; Hypertension

1980
Triphasic waves in serotonin syndrome.
    Journal of neurology, neurosurgery, and psychiatry, 1997, Volume: 62, Issue:2

    Topics: 1-Naphthylamine; Aged; Amantadine; Antiparkinson Agents; Brain Diseases; Carbidopa; Drug Combination

1997
Effects of dopaminergic combination therapy for frontal lobe dysfunction in traumatic brain injury rehabilitation.
    Brain injury, 1999, Volume: 13, Issue:1

    Topics: Accidental Falls; Adult; Akathisia, Drug-Induced; Amantadine; Brain Injuries; Bromocriptine; Dopamin

1999
Visual hallucinations and delirium during treatment with amantadine (Symmetrel).
    Journal of the American Geriatrics Society, 1975, Volume: 23, Issue:5

    Topics: Aged; Amantadine; Benztropine; Biperiden; Delirium; Drug Eruptions; Female; Hallucinations; Humans;

1975
Amantadine neurotoxicity in a pediatric patient with renal insufficiency.
    DICP : the annals of pharmacotherapy, 1991, Volume: 25, Issue:11

    Topics: Adolescent; Amantadine; Central Nervous System Diseases; Creatine; Female; Graft Rejection; Hallucin

1991
Amantadine toxicity presenting with complex ventricular ectopy and hallucinations.
    Pediatric emergency care, 1991, Volume: 7, Issue:2

    Topics: Adolescent; Amantadine; Arrhythmias, Cardiac; Charcoal; Drug Overdose; Electrocardiography; Emergenc

1991
Acute psychosis after amantadine overdose.
    Annals of emergency medicine, 1990, Volume: 19, Issue:6

    Topics: Adult; Amantadine; Diagnosis, Differential; Diphenhydramine; Drug Synergism; Female; Hallucinations;

1990
Visual hallucinations. The unwanted effect of patient compliance.
    Australian family physician, 1985, Volume: 14, Issue:8

    Topics: Aged; Amantadine; Female; Hallucinations; Humans; Patient Compliance; Vision Disorders

1985
[Amantadine in the treatment of Parkinson's disease].
    Revue medicale de Liege, 1972, Dec-01, Volume: 27, Issue:23

    Topics: Amantadine; Drug Eruptions; Hallucinations; Humans; Parkinson Disease; Time Factors

1972
L-dopa for parkinsonism.
    Geriatrics, 1973, Volume: 28, Issue:1

    Topics: Aged; Amantadine; Depression; Dihydroxyphenylalanine; Female; Follow-Up Studies; Hallucinations; Hum

1973
Coloured Lilliputian hallucinations with amantadine.
    The Medical journal of Australia, 1973, Mar-03, Volume: 1, Issue:9

    Topics: Aged; Amantadine; Female; Hallucinations; Humans; Male; Parkinson Disease; Tremor; Visual Pathways

1973
[Amantadine treatment in parkinsonism].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1973, Oct-10, Volume: 93, Issue:28

    Topics: Administration, Oral; Amantadine; Anxiety; Hallucinations; Humans; Parkinson Disease; Sleep Wake Dis

1973
L-dopa treatment of parkinsonism. Clinical observations on the use of amantadine hydrochloride.
    Geriatrics, 1971, Volume: 26, Issue:8

    Topics: Aged; Amantadine; Chlorides; Depression; Dihydroxyphenylalanine; Drug Hypersensitivity; Female; Foll

1971