Page last updated: 2024-10-22

amantadine and Guillain-Barre Syndrome

amantadine has been researched along with Guillain-Barre Syndrome in 9 studies

amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source

Guillain-Barre Syndrome: An acute inflammatory autoimmune neuritis caused by T cell- mediated cellular immune response directed towards peripheral myelin. Demyelination occurs in peripheral nerves and nerve roots. The process is often preceded by a viral or bacterial infection, surgery, immunization, lymphoma, or exposure to toxins. Common clinical manifestations include progressive weakness, loss of sensation, and loss of deep tendon reflexes. Weakness of respiratory muscles and autonomic dysfunction may occur. (From Adams et al., Principles of Neurology, 6th ed, pp1312-1314)

Research Excerpts

ExcerptRelevanceReference
"Amantadine was not superior to placebo."6.72Amantadine for treatment of fatigue in Guillain-Barre syndrome: a randomised, double blind, placebo controlled, crossover trial. ( Garssen, MP; Jacobs, BC; Merkies, IS; Schmitz, PI; van der Meché, FG; van Doorn, PA, 2006)
" The effects of amantadine from one randomised, double-blind, placebo-controlled, cross-over trial comparing amantadine with placebo for the treatment of fatigue in 80 people with Guillain-Barré syndrome (GBS) were uncertain for the proportion of people achieving a favourable outcome six weeks post-intervention (odds ratio (OR) 0."4.90Interventions for fatigue in peripheral neuropathy. ( Garssen, MP; Stockley, RC; van Doorn, PA; White, CM, 2014)
"The most common subtypes of GBS are acute inflammatory demyelinating polyneuropathy (AIDP) and acute motor axonal neuropathy (AMAN)."2.82Triggers of Guillain-Barré Syndrome: ( Finsterer, J, 2022)
"Amantadine was not superior to placebo."2.72Amantadine for treatment of fatigue in Guillain-Barre syndrome: a randomised, double blind, placebo controlled, crossover trial. ( Garssen, MP; Jacobs, BC; Merkies, IS; Schmitz, PI; van der Meché, FG; van Doorn, PA, 2006)
"The final subtype diagnosis was acute inflammatory demyelinating polyneuropathy (AIDP) in 16 patients (six met the criteria at the initial EDx study and 10 at follow-up) and acute motor axonal neuropathy (AMAN) in 10 patients (six initially)."1.91Identical late motor responses in early Guillain-Barré syndrome: A-waves and repeater F-waves. ( Chroni, E; Kefalopoulou, Z; Kintos, V; Veltsista, D, 2023)
"Several reports of RCF in acute inflammatory demyelinating polyneuropathy (AIDP) have suggested that it could be a manifestation of nodopathy."1.72Reversible conduction failure in acute inflammatory demyelinating polyneuropathy. ( Kim, S; Lee, EK; Sohn, E, 2022)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's2 (22.22)24.3611
2020's6 (66.67)2.80

Authors

AuthorsStudies
Kalita, J1
Misra, UK1
Chaudhary, SK1
Das, M1
Mishra, A1
Ranjan, A1
Kumar, M1
Kim, S2
Lee, EK2
Sohn, E2
Finsterer, J3
Veltsista, D3
Kefalopoulou, Z3
Kintos, V3
Chroni, E3
Jo, N1
Agarwal, E1
Bhagat, A1
Srivastava, K1
Thakore, B1
Jagtap, S1
Kalane, U1
Rajadhyaksha, S1
Gupta, J1
Jauhari, P1
White, CM1
van Doorn, PA2
Garssen, MP2
Stockley, RC1
Schmitz, PI1
Merkies, IS1
Jacobs, BC1
van der Meché, FG1

Reviews

3 reviews available for amantadine and Guillain-Barre Syndrome

ArticleYear
Triggers of Guillain-Barré Syndrome:
    International journal of molecular sciences, 2022, Nov-17, Volume: 23, Issue:22

    Topics: Amantadine; Autoantibodies; Axons; Campylobacter jejuni; Guillain-Barre Syndrome; Humans

2022
Triggers of Guillain-Barré Syndrome:
    International journal of molecular sciences, 2022, Nov-17, Volume: 23, Issue:22

    Topics: Amantadine; Autoantibodies; Axons; Campylobacter jejuni; Guillain-Barre Syndrome; Humans

2022
Triggers of Guillain-Barré Syndrome:
    International journal of molecular sciences, 2022, Nov-17, Volume: 23, Issue:22

    Topics: Amantadine; Autoantibodies; Axons; Campylobacter jejuni; Guillain-Barre Syndrome; Humans

2022
Triggers of Guillain-Barré Syndrome:
    International journal of molecular sciences, 2022, Nov-17, Volume: 23, Issue:22

    Topics: Amantadine; Autoantibodies; Axons; Campylobacter jejuni; Guillain-Barre Syndrome; Humans

2022
Triggers of Guillain-Barré Syndrome:
    International journal of molecular sciences, 2022, Nov-17, Volume: 23, Issue:22

    Topics: Amantadine; Autoantibodies; Axons; Campylobacter jejuni; Guillain-Barre Syndrome; Humans

2022
Triggers of Guillain-Barré Syndrome:
    International journal of molecular sciences, 2022, Nov-17, Volume: 23, Issue:22

    Topics: Amantadine; Autoantibodies; Axons; Campylobacter jejuni; Guillain-Barre Syndrome; Humans

2022
Triggers of Guillain-Barré Syndrome:
    International journal of molecular sciences, 2022, Nov-17, Volume: 23, Issue:22

    Topics: Amantadine; Autoantibodies; Axons; Campylobacter jejuni; Guillain-Barre Syndrome; Humans

2022
Triggers of Guillain-Barré Syndrome:
    International journal of molecular sciences, 2022, Nov-17, Volume: 23, Issue:22

    Topics: Amantadine; Autoantibodies; Axons; Campylobacter jejuni; Guillain-Barre Syndrome; Humans

2022
Triggers of Guillain-Barré Syndrome:
    International journal of molecular sciences, 2022, Nov-17, Volume: 23, Issue:22

    Topics: Amantadine; Autoantibodies; Axons; Campylobacter jejuni; Guillain-Barre Syndrome; Humans

2022
How Important it is to Differentiate AMAN from AIDP in Childhood GBS? A Clinician's Perspective.
    Indian journal of pediatrics, 2019, Volume: 86, Issue:4

    Topics: Amantadine; Child; Guillain-Barre Syndrome; Humans; India; Prospective Studies

2019
Interventions for fatigue in peripheral neuropathy.
    The Cochrane database of systematic reviews, 2014, Dec-18, Issue:12

    Topics: Adult; Amantadine; Ascorbic Acid; Charcot-Marie-Tooth Disease; Child; Fatigue; Guillain-Barre Syndro

2014

Trials

1 trial available for amantadine and Guillain-Barre Syndrome

ArticleYear
Amantadine for treatment of fatigue in Guillain-Barre syndrome: a randomised, double blind, placebo controlled, crossover trial.
    Journal of neurology, neurosurgery, and psychiatry, 2006, Volume: 77, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amantadine; Antiviral Agents; Anxiety; Cross-Over Studies; Depressio

2006

Other Studies

5 other studies available for amantadine and Guillain-Barre Syndrome

ArticleYear
Outcome of Guillain-Barré syndrome following intravenous immunoglobulin compared to natural course.
    European journal of neurology, 2022, Volume: 29, Issue:10

    Topics: Amantadine; Guillain-Barre Syndrome; Hospital Mortality; Humans; Immunoglobulins, Intravenous; Respi

2022
Reversible conduction failure in acute inflammatory demyelinating polyneuropathy.
    Scientific reports, 2022, 11-03, Volume: 12, Issue:1

    Topics: Amantadine; Gangliosides; Guillain-Barre Syndrome; Heart Rate; Humans; Neural Conduction

2022
Identical late motor responses in early Guillain-Barré syndrome: A-waves and repeater F-waves.
    Journal of the peripheral nervous system : JPNS, 2023, Volume: 28, Issue:1

    Topics: Amantadine; Guillain-Barre Syndrome; Humans; Neural Conduction; Retrospective Studies

2023
Identical late motor responses in early Guillain-Barré syndrome: A-waves and repeater F-waves.
    Journal of the peripheral nervous system : JPNS, 2023, Volume: 28, Issue:1

    Topics: Amantadine; Guillain-Barre Syndrome; Humans; Neural Conduction; Retrospective Studies

2023
Identical late motor responses in early Guillain-Barré syndrome: A-waves and repeater F-waves.
    Journal of the peripheral nervous system : JPNS, 2023, Volume: 28, Issue:1

    Topics: Amantadine; Guillain-Barre Syndrome; Humans; Neural Conduction; Retrospective Studies

2023
Identical late motor responses in early Guillain-Barré syndrome: A-waves and repeater F-waves.
    Journal of the peripheral nervous system : JPNS, 2023, Volume: 28, Issue:1

    Topics: Amantadine; Guillain-Barre Syndrome; Humans; Neural Conduction; Retrospective Studies

2023
Association between hyperCKemia and axonal degeneration in Guillain-Barré syndrome.
    BMC neurology, 2023, Mar-02, Volume: 23, Issue:1

    Topics: Amantadine; Axons; Guillain-Barre Syndrome; Hospitalization; Humans; Nerve Conduction Studies; Retro

2023
Clinical and Electrophysiological Factors Predicting Prolonged Recovery in Children with Guillain-Barré Syndrome.
    Indian journal of pediatrics, 2022, Volume: 89, Issue:5

    Topics: Amantadine; Child; Guillain-Barre Syndrome; Humans; Neural Conduction; Neurologic Examination; Progn

2022