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amantadine and Glioma

amantadine has been researched along with Glioma in 4 studies

amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
" For this purpose, we measured the modulation of GDNF release in C6 glioma cell cultures treated for 24 h with amantadine and memantine."7.73Amantadine and memantine induce the expression of the glial cell line-derived neurotrophic factor in C6 glioma cells. ( Caumont, AS; Hermans, E; Octave, JN, 2006)
" For this purpose, we measured the modulation of GDNF release in C6 glioma cell cultures treated for 24 h with amantadine and memantine."3.73Amantadine and memantine induce the expression of the glial cell line-derived neurotrophic factor in C6 glioma cells. ( Caumont, AS; Hermans, E; Octave, JN, 2006)
"Serotonin (5-HT) evoked a rise of cytosolic Ca2+ activity in neuroblastoma X glioma hybrid cells, most probably due to the entry of extracellular Ca2+; cyclic GMP synthesis was also stimulated."3.67Memantine inhibits serotonin-induced rise of cytosolic Ca2+ activity and of cyclic GMP level in a neuronal cell line. ( Koch, R; Reiser, G, 1989)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Caumont, AS1
Octave, JN1
Hermans, E1
Sundberg, AL1
Steffen, AC1
Reiser, G2
Koch, R2
Binmöller, FJ1

Other Studies

4 other studies available for amantadine and Glioma

ArticleYear
Amantadine and memantine induce the expression of the glial cell line-derived neurotrophic factor in C6 glioma cells.
    Neuroscience letters, 2006, Feb-20, Volume: 394, Issue:3

    Topics: 5' Untranslated Regions; Amantadine; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dopa

2006
Enhancing the effect of radionuclide tumor targeting, using lysosomotropic weak bases.
    International journal of radiation oncology, biology, physics, 2007, Jan-01, Volume: 67, Issue:1

    Topics: Amantadine; Ammonium Chloride; Antimalarials; Antipsychotic Agents; Antiviral Agents; Astatine; Carc

2007
Memantine inhibits serotonin-induced rise of cytosolic Ca2+ activity and of cyclic GMP level in a neuronal cell line.
    European journal of pharmacology, 1989, May-11, Volume: 172, Issue:2

    Topics: Amantadine; Animals; Calcium; Cyclic GMP; Cytosol; Glioma; Memantine; Nervous System Neoplasms; Neur

1989
Memantine (1-amino-3,5-dimethyladamantane) blocks the serotonin-induced depolarization response in a neuronal cell line.
    Brain research, 1988, Mar-08, Volume: 443, Issue:1-2

    Topics: Amantadine; Animals; Calcium; Cell Line; Glioma; Hybrid Cells; Memantine; Membrane Potentials; Neuro

1988