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amantadine and Epilepsy, Absence

amantadine has been researched along with Epilepsy, Absence in 5 studies

amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source

Epilepsy, Absence: A seizure disorder usually occurring in childhood characterized by rhythmic electrical brain discharges of generalized onset. Clinical features include a sudden cessation of ongoing activity usually without loss of postural tone. Rhythmic blinking of the eyelids or lip smacking frequently accompanies the SEIZURES. The usual duration is 5-10 seconds, and multiple episodes may occur daily. Juvenile absence epilepsy is characterized by the juvenile onset of absence seizures and an increased incidence of myoclonus and tonic-clonic seizures. (Menkes, Textbook of Child Neurology, 5th ed, p736)

Research Excerpts

ExcerptRelevanceReference
"Amantadine has demonstrated efficacy in small series for absence and myoclonic type seizures."1.38Amantadine for the treatment of refractory absence seizures in children. ( Bailey, LJ; Hernandez, AW; Kotecha, AC; Malik, SI; Perry, MS, 2012)
"Amantadine hydrochloride was administered as an add-on drug to four children with refractory absence epilepsy, resulting in complete resolution of absence episodes within 1 week."1.28Effect of add-on amantadine therapy for refractory absence epilepsy. ( Brand, N; Shahar, EM, 1992)
"Amantadine was added to the existing regimens in weekly increments to 400 mg/day."1.28Amantadine hydrochloride for refractory generalized epilepsy in adults. ( Denio, LS; Drake, ME; Pakalnis, A; Phillips, B, 1991)
"Amantadine HCl was given to 10 children with medically refractory seizures; other anticonvulsant medications were continued unchanged through the 12- to 16-week trial."1.27Amantadine in the treatment of refractory epilepsy in childhood: an open trial in 10 patients. ( Chugani, HT; Lake, JL; Shields, WD, 1985)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Perry, MS1
Bailey, LJ1
Kotecha, AC1
Malik, SI1
Hernandez, AW1
Matsushige, T1
Matsufuji, H1
Ichiyama, T1
Furukawa, S1
Shahar, EM1
Brand, N1
Drake, ME1
Pakalnis, A1
Denio, LS1
Phillips, B1
Shields, WD1
Lake, JL1
Chugani, HT1

Other Studies

5 other studies available for amantadine and Epilepsy, Absence

ArticleYear
Amantadine for the treatment of refractory absence seizures in children.
    Pediatric neurology, 2012, Volume: 46, Issue:4

    Topics: Amantadine; Child; Child, Preschool; Dopamine Agents; Epilepsy, Absence; Female; Follow-Up Studies;

2012
[A girl with refractory childhood absence epilepsy improved by add-on amantadine therapy].
    No to hattatsu = Brain and development, 2007, Volume: 39, Issue:4

    Topics: Amantadine; Anticonvulsants; Child; Drug Administration Schedule; Electroencephalography; Epilepsy,

2007
Effect of add-on amantadine therapy for refractory absence epilepsy.
    The Journal of pediatrics, 1992, Volume: 121, Issue:5 Pt 1

    Topics: Amantadine; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Electroencephalogra

1992
Amantadine hydrochloride for refractory generalized epilepsy in adults.
    Acta neurologica Belgica, 1991, Volume: 91, Issue:3

    Topics: Adolescent; Adult; Amantadine; Anticonvulsants; Epilepsy, Absence; Epilepsy, Generalized; Epilepsy,

1991
Amantadine in the treatment of refractory epilepsy in childhood: an open trial in 10 patients.
    Neurology, 1985, Volume: 35, Issue:4

    Topics: Adolescent; Amantadine; Child; Child, Preschool; Epilepsies, Myoclonic; Epilepsy, Absence; Female; H

1985