Page last updated: 2024-10-22

amantadine and Emesis, Postoperative

amantadine has been researched along with Emesis, Postoperative in 2 studies

amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source

Research Excerpts

ExcerptRelevanceReference
"Amantadine is known to be a noncompetitive N-methyl-D-aspartate receptor antagonist and may be useful in preventing postoperative central sensitization, acute opioid tolerance, and opioid-induced hyperalgesia, thereby decreasing pain and analgesic requirements."2.71Effects of perioperative oral amantadine on postoperative pain and morphine consumption in patients after radical prostatectomy: results of a preliminary study. ( Katz, J; Koren, G; Snijdelaar, DG, 2004)
"Because of no differences in postoperative pain or opioid consumption, we conclude that a preoperative dose of 200 mg amantadine IV fails to enhance postoperative analgesia in patients undergoing elective abdominal hysterectomy."2.70Amantadine, a N-methyl-D-aspartate receptor antagonist, does not enhance postoperative analgesia in women undergoing abdominal hysterectomy. ( Buerkle, H; Gottschalk, A; Oncü, A; Schroeder, F; Standl, T; Ufer, M, 2001)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Snijdelaar, DG1
Koren, G1
Katz, J1
Gottschalk, A1
Schroeder, F1
Ufer, M1
Oncü, A1
Buerkle, H1
Standl, T1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phenomics and Genomics of Clinically Relevant Chronic Postsurgical Pain: A Multicenter Prospective Study[NCT04798573]10,000 participants (Anticipated)Observational2012-08-03Active, not recruiting
The Implications of Amantadine Sulphate Usage in Spine Deformities Corrective Surgeries Patients as Regard Its Effect on the Duration of Wake up Test and Postoperative Opioid Consumption[NCT03178708]Phase 2/Phase 360 participants (Actual)Interventional2017-08-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for amantadine and Emesis, Postoperative

ArticleYear
Effects of perioperative oral amantadine on postoperative pain and morphine consumption in patients after radical prostatectomy: results of a preliminary study.
    Anesthesiology, 2004, Volume: 100, Issue:1

    Topics: Adolescent; Adult; Aged; Amantadine; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Gener

2004
Effects of perioperative oral amantadine on postoperative pain and morphine consumption in patients after radical prostatectomy: results of a preliminary study.
    Anesthesiology, 2004, Volume: 100, Issue:1

    Topics: Adolescent; Adult; Aged; Amantadine; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Gener

2004
Effects of perioperative oral amantadine on postoperative pain and morphine consumption in patients after radical prostatectomy: results of a preliminary study.
    Anesthesiology, 2004, Volume: 100, Issue:1

    Topics: Adolescent; Adult; Aged; Amantadine; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Gener

2004
Effects of perioperative oral amantadine on postoperative pain and morphine consumption in patients after radical prostatectomy: results of a preliminary study.
    Anesthesiology, 2004, Volume: 100, Issue:1

    Topics: Adolescent; Adult; Aged; Amantadine; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Gener

2004
Amantadine, a N-methyl-D-aspartate receptor antagonist, does not enhance postoperative analgesia in women undergoing abdominal hysterectomy.
    Anesthesia and analgesia, 2001, Volume: 93, Issue:1

    Topics: Aged; Amantadine; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Double-Blind Me

2001