amantadine has been researched along with Delayed Hypersensitivity in 4 studies
amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source
| Excerpt | Relevance | Reference |
|---|---|---|
| "The adjuvant effect of a novel synthetic compound adamantylamide dipeptide (AdDP) was tested in a model of delayed hypersensitivity to ovalbumin in guinea pigs, and of immunostimulatory activity in the experiments with 3H thymidine where DNA biosynthesis was measured in several immunocompetent organs after administration of adamantylamide dipeptide." | 3.67 | The immunomodulatory property of a novel synthetic compound adamantylamide dipeptide. ( Flegel, M; Kolínsky, J; Krojidlo, M; Masek, K; Seifert, J, 1984) |
| " This effort led to the discovery of 1-methyl-3-(4-methylpyridin-3-yl)-6-(pyridin-2-ylmethoxy)-1H-pyrazolo[3,4-b]pyrazine (PF470, 14) as a highly potent, selective, and orally bioavailable mGluR5 NAM." | 1.40 | Discovery and preclinical characterization of 1-methyl-3-(4-methylpyridin-3-yl)-6-(pyridin-2-ylmethoxy)-1H-pyrazolo-[3,4-b]pyrazine (PF470): a highly potent, selective, and efficacious metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulat ( Balan, G; Barreiro, G; Boscoe, BP; Chen, L; Chenard, LK; Cianfrogna, J; Claffey, MM; Coffman, KJ; Drozda, SE; Dunetz, JR; Fonseca, KR; Galatsis, P; Grimwood, S; Lazzaro, JT; Mancuso, JY; Miller, EL; Reese, MR; Rogers, BN; Sakurada, I; Shaffer, CL; Skaddan, M; Smith, DL; Stepan, AF; Trapa, P; Tuttle, JB; Verhoest, PR; Walker, DP; Wright, AS; Zaleska, MM; Zasadny, K; Zhang, L, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, L | 1 |
| Balan, G | 1 |
| Barreiro, G | 1 |
| Boscoe, BP | 1 |
| Chenard, LK | 1 |
| Cianfrogna, J | 1 |
| Claffey, MM | 1 |
| Chen, L | 1 |
| Coffman, KJ | 1 |
| Drozda, SE | 1 |
| Dunetz, JR | 1 |
| Fonseca, KR | 1 |
| Galatsis, P | 1 |
| Grimwood, S | 1 |
| Lazzaro, JT | 1 |
| Mancuso, JY | 1 |
| Miller, EL | 1 |
| Reese, MR | 1 |
| Rogers, BN | 1 |
| Sakurada, I | 1 |
| Skaddan, M | 1 |
| Smith, DL | 1 |
| Stepan, AF | 1 |
| Trapa, P | 1 |
| Tuttle, JB | 1 |
| Verhoest, PR | 1 |
| Walker, DP | 1 |
| Wright, AS | 1 |
| Zaleska, MM | 1 |
| Zasadny, K | 1 |
| Shaffer, CL | 1 |
| Masek, K | 2 |
| Seifert, J | 1 |
| Flegel, M | 1 |
| Krojidlo, M | 1 |
| Kolínsky, J | 1 |
| Masihi, KN | 1 |
| Rohde-Schulz, B | 1 |
| Palache, B | 1 |
| Katz, SL | 1 |
2 reviews available for amantadine and Delayed Hypersensitivity
| Article | Year |
|---|---|
Antiviral and adjuvant activity of immunomodulator adamantylamide dipeptide.
Topics: Adjuvants, Immunologic; Amantadine; Animals; Antibodies, Viral; Antiviral Agents; Dipeptides; Hypers | 1992 |
Advances in the treatment of virus diseases.
Topics: Amantadine; Antibodies; gamma-Globulins; Humans; Hypersensitivity, Delayed; Idoxuridine; Interferons | 1968 |
2 other studies available for amantadine and Delayed Hypersensitivity
| Article | Year |
|---|---|
Discovery and preclinical characterization of 1-methyl-3-(4-methylpyridin-3-yl)-6-(pyridin-2-ylmethoxy)-1H-pyrazolo-[3,4-b]pyrazine (PF470): a highly potent, selective, and efficacious metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulat
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Administration, Oral; Allosteric Regulation; Animals; | 2014 |
The immunomodulatory property of a novel synthetic compound adamantylamide dipeptide.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adjuvants, Immunologic; Amantadine; Animals; Chemical Phenomena; | 1984 |