amantadine has been researched along with Cystic Fibrosis in 1 studies
amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source
Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amantadine-HC1, an antiviral drug clinically effective against most strains of influenza A virus, was evaluated in a double-blind trial in 153 children with cystic fibrosis during the initial appearance of influenza A/England/42 virus in the New England area." | 9.04 | Evaluation of the safety of amantadine-HC1 and the role of respiratory viral infections in children with cystic fibrosis. ( Khaw, KT; Oxman, MN; Shwachman, H; Wright, PF, 1976) |
| "Amantadine-HC1, an antiviral drug clinically effective against most strains of influenza A virus, was evaluated in a double-blind trial in 153 children with cystic fibrosis during the initial appearance of influenza A/England/42 virus in the New England area." | 5.04 | Evaluation of the safety of amantadine-HC1 and the role of respiratory viral infections in children with cystic fibrosis. ( Khaw, KT; Oxman, MN; Shwachman, H; Wright, PF, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wright, PF | 1 |
| Khaw, KT | 1 |
| Oxman, MN | 1 |
| Shwachman, H | 1 |
1 trial available for amantadine and Cystic Fibrosis
| Article | Year |
|---|---|
Evaluation of the safety of amantadine-HC1 and the role of respiratory viral infections in children with cystic fibrosis.
Topics: Adolescent; Adult; Amantadine; Child; Child, Preschool; Clinical Trials as Topic; Cystic Fibrosis; F | 1976 |