amantadine has been researched along with Colonic Neoplasms in 5 studies
amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In search for novel strategies in colon cancer treatment, we investigated the unique ability of platinum(IV) complex LA-12 to efficiently enhance the killing effects of tumor necrosis factor-related apoptosis inducing ligand (TRAIL), and compared it with the sensitizing action of cisplatin." | 1.40 | Platinum(IV) complex LA-12 exerts higher ability than cisplatin to enhance TRAIL-induced cancer cell apoptosis via stimulation of mitochondrial pathway. ( Ehrmann, J; Hofmanová, J; Hyršlová Vaculová, A; Jelínková, I; Kolář, Z; Kozubík, A; Moyer, MP; Šafaříková, B; Skender, B; Sova, P; Vondálová Blanářová, O, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vondálová Blanářová, O | 2 |
| Jelínková, I | 2 |
| Hyršlová Vaculová, A | 3 |
| Sova, P | 5 |
| Hofmanová, J | 4 |
| Kozubík, A | 4 |
| Šafaříková, B | 1 |
| Skender, B | 1 |
| Moyer, MP | 2 |
| Kolář, Z | 1 |
| Ehrmann, J | 2 |
| Lauková, J | 1 |
| Nekvindová, J | 1 |
| Svihálková-Sindlerová, L | 1 |
| Foltinová, V | 1 |
| Vaculová, A | 1 |
| Horváth, V | 1 |
| Soucek, K | 1 |
| Mistr, A | 1 |
| Kroutil, A | 1 |
| Zak, F | 1 |
| Pouckova, P | 1 |
| Zadinova, M | 1 |
5 other studies available for amantadine and Colonic Neoplasms
| Article | Year |
|---|---|
Higher anti-tumour efficacy of platinum(IV) complex LA-12 is associated with its ability to bypass M-phase entry block induced in oxaliplatin-treated human colon cancer cells.
Topics: Adenocarcinoma; Amantadine; Antineoplastic Agents; Apoptosis; Cell Division; Cell Line, Tumor; Cell | 2013 |
Platinum(IV) complex LA-12 exerts higher ability than cisplatin to enhance TRAIL-induced cancer cell apoptosis via stimulation of mitochondrial pathway.
Topics: Amantadine; Antineoplastic Agents; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Asso | 2014 |
Loss of PTEN Facilitates Rosiglitazone-Mediated Enhancement of Platinum(IV) Complex LA-12-Induced Apoptosis in Colon Cancer Cells.
Topics: Amantadine; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colo | 2015 |
LA-12 overcomes confluence-dependent resistance of HT-29 colon cancer cells to Pt (II) compounds.
Topics: Adenocarcinoma; Amantadine; Antineoplastic Agents; Apoptosis; Cell Adhesion; Cisplatin; Colonic Neop | 2010 |
Comparative anti-tumor efficacy of two orally administered platinum(IV) drugs in nude mice bearing human tumor xenografts.
Topics: Amantadine; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cisplatin; Colonic Neop | 2006 |