amantadine has been researched along with Chronic Kidney Failure in 20 studies
amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amantadine toxicity is a particular problem in patients with renal insufficiency because 90% of an oral dose is excreted unchanged in the urine." | 5.29 | Amantadine-induced coma. ( Ito, V; Macchio, GJ; Sahgal, V, 1993) |
| " We included studies investigating pemoline and modafinil in participants with multiple sclerosis (MS)-associated fatigue and methylphenidate in patients suffering from advanced cancer and fatigue in meta-analysis." | 4.91 | Pharmacological treatments for fatigue associated with palliative care. ( Cuhls, H; Minton, O; Mücke, M; Peuckmann-Post, V; Radbruch, L; Stone, P, 2015) |
| " Studies investigating amantadine, pemoline, and modafinil in participants with Multiple Sclerosis (MS)-associated fatigue and methylphenidate in patients suffering from advanced cancer and fatigue could be used for meta-analysis." | 4.86 | Pharmacological treatments for fatigue associated with palliative care. ( Elsner, F; Krumm, N; Peuckmann, V; Radbruch, L; Trottenberg, P, 2010) |
| " Plasma half-life averaged 68." | 2.65 | Amantadine hydrochloride pharmacokinetics in patients with impaired renal function. ( Daugirdas, JT; Gandhi, VC; Hano, JE; Ing, TS; Soung, LS; Wu, MJ, 1982) |
| "To provide a review of rimantadine, including its antiviral activity, pharmacokinetics, efficacy, adverse effects, drug interactions, and dosage and administration." | 2.39 | Rimantadine: a clinical perspective. ( Nahata, MC; Wintermeyer, SM, 1995) |
| " Therefore, their interchangeable use cannot be advocated in the dosing of medications until further prospective validations are performed." | 1.34 | Use of GFR equations to adjust drug doses in an elderly multi-ethnic group--a cautionary tale. ( Djurdjev, O; Gill, J; Levin, A; Malyuk, R, 2007) |
| "Amantadine toxicity is a particular problem in patients with renal insufficiency because 90% of an oral dose is excreted unchanged in the urine." | 1.29 | Amantadine-induced coma. ( Ito, V; Macchio, GJ; Sahgal, V, 1993) |
| " The half-life of elimination in subjects with normal renal function was 11." | 1.26 | Pharmacokinetics of amantadine hydrochloride in subjects with normal and impaired renal function. ( Brater, DC; Garriott, JC; Horadam, VW; McAnalley, BH; Prati, RC; Sharp, JG; Smilack, JD; Stephens, MK, 1981) |
| " The average half-life of amantadine in eight patients studied while receiving maintenance hemodialysis was 24." | 1.26 | Amantadine hydrochloride pharmacokinetics in hemodialysis patients. ( Daugirdas, JT; Gandhi, VC; Hano, JE; Ing, TS; Ivanovich, PT; Soung, LS; Viol, GW; Wu, MJ, 1980) |
| "Two patients with Parkinson's disease and renal insufficiency had excessively high concentrations of amantadine hydrochloride in the blood." | 1.26 | Removal of amantadine hydrochloride by dialysis in patients with renal insufficiency. ( Dunea, G; Hayashi, JA; Ing, TS; Klawans, HL; Mahurkar, SD; Markey, WS, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (50.00) | 18.7374 |
| 1990's | 3 (15.00) | 18.2507 |
| 2000's | 5 (25.00) | 29.6817 |
| 2010's | 2 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mücke, M | 1 |
| Cuhls, H | 1 |
| Peuckmann-Post, V | 1 |
| Minton, O | 1 |
| Stone, P | 1 |
| Radbruch, L | 2 |
| Michalski, LS | 1 |
| Hantsch Bardsley, C | 1 |
| Holt, DR | 1 |
| Milner, JE | 1 |
| Hou, SH | 1 |
| Peuckmann, V | 1 |
| Elsner, F | 1 |
| Krumm, N | 1 |
| Trottenberg, P | 1 |
| Myers, JW | 1 |
| Gill, J | 1 |
| Malyuk, R | 1 |
| Djurdjev, O | 1 |
| Levin, A | 1 |
| Goforth, H | 1 |
| Cheng, PL | 1 |
| Hung, SW | 1 |
| Lin, LW | 1 |
| Chong, CF | 1 |
| Lau, CI | 1 |
| Ing, TS | 7 |
| Cheng, PJ | 2 |
| Wu, MJ | 4 |
| Daugirdas, JT | 5 |
| Soung, LS | 5 |
| Ing, IL | 1 |
| Klawans, HL | 5 |
| Hano, JE | 3 |
| Gandhi, VC | 2 |
| Horadam, VW | 1 |
| Sharp, JG | 1 |
| Smilack, JD | 1 |
| McAnalley, BH | 1 |
| Garriott, JC | 1 |
| Stephens, MK | 1 |
| Prati, RC | 1 |
| Brater, DC | 1 |
| Ivanovich, PT | 1 |
| Viol, GW | 1 |
| Wintermeyer, SM | 1 |
| Nahata, MC | 1 |
| Miller, KS | 1 |
| Miller, JM | 1 |
| Macchio, GJ | 1 |
| Ito, V | 1 |
| Sahgal, V | 1 |
| Mahurkar, SD | 2 |
| Hayashi, JA | 2 |
| Geis, WP | 1 |
| Borison, RL | 1 |
| Dunea, G | 1 |
| Markey, WS | 1 |
| Rahn, AC | 2 |
| Armbruster, KF | 2 |
| Oyama, JH | 2 |
| Halper, IS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Feasibility Study of Adjunctive Bright Light Therapy (BLT) for Amelioration of Fatigue in Chinese Cancer Patients Admitted to a Palliative Care Unit[NCT04525924] | 42 participants (Anticipated) | Interventional | 2020-08-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for amantadine and Chronic Kidney Failure
| Article | Year |
|---|---|
Pharmacological treatments for fatigue associated with palliative care.
Topics: Adult; Amantadine; Benzhydryl Compounds; Carnitine; Central Nervous System Stimulants; Chronic Disea | 2015 |
Pharmacological treatments for fatigue associated with palliative care.
Topics: Adult; Amantadine; Benzhydryl Compounds; Central Nervous System Stimulants; Fatigue; Humans; Kidney | 2010 |
Influenza therapy.
Topics: Acetamides; Adult; Age Factors; Amantadine; Antiviral Agents; Child; Cost-Benefit Analysis; Creatine | 2003 |
Rimantadine: a clinical perspective.
Topics: Absorption; Amantadine; Controlled Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Comb | 1995 |
1 trial available for amantadine and Chronic Kidney Failure
| Article | Year |
|---|---|
Amantadine hydrochloride pharmacokinetics in patients with impaired renal function.
Topics: Adult; Amantadine; Antiviral Agents; Clinical Trials as Topic; Creatinine; Drug Evaluation; Humans; | 1982 |
15 other studies available for amantadine and Chronic Kidney Failure
| Article | Year |
|---|---|
Altered mental status in a transplant patient. Amantadine toxicity.
Topics: Adult; Amantadine; Confusion; Diabetes Complications; Diabetes Mellitus, Type 1; Female; Hallucinati | 2009 |
Use of GFR equations to adjust drug doses in an elderly multi-ethnic group--a cautionary tale.
Topics: Aged; Aged, 80 and over; Algorithms; Amantadine; Asian People; Creatinine; Digoxin; Drug Administrat | 2007 |
Amantadine in catatonia due to major depressive disorder in a medically ill patient.
Topics: Adult; Amantadine; Antiparkinson Agents; Catatonia; Depressive Disorder, Major; Electroconvulsive Th | 2007 |
Amantadine-induced serotonin syndrome in a patient with renal failure.
Topics: Aged; Amantadine; Antiparkinson Agents; Comorbidity; Electroencephalography; Humans; Kidney Failure, | 2008 |
Plasma protein-binding of amantadine in maintenance hemodialysis patients.
Topics: Amantadine; Blood Proteins; Humans; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Ultr | 1984 |
Binding of amantadine to red blood cells.
Topics: Adult; Aged; Amantadine; Binding Sites; Dose-Response Relationship, Drug; Erythrocytes; Female; Huma | 1984 |
Pharmacokinetics of amantadine hydrochloride in subjects with normal and impaired renal function.
Topics: Adult; Aged; Amantadine; Creatinine; Female; Half-Life; Humans; Kidney; Kidney Failure, Chronic; Kin | 1981 |
Amantadine hydrochloride pharmacokinetics in hemodialysis patients.
Topics: Amantadine; Half-Life; Humans; Influenza, Human; Kidney Failure, Chronic; Kinetics; Renal Dialysis | 1980 |
Toxic effects of amantadine in patients with renal failure.
Topics: Amantadine; Female; Humans; Kidney Failure, Chronic; Middle Aged; Muscular Diseases; Poisoning | 1994 |
Amantadine-induced coma.
Topics: Adult; Amantadine; Coma; Humans; Kidney Failure, Chronic; Male; Multiple Sclerosis | 1993 |
Toxic effects of amantadine in patients with renal failure.
Topics: Acute Kidney Injury; Adult; Aged; Amantadine; Female; Humans; Kidney Failure, Chronic; Male; Middle | 1979 |
Amantadine-induced psychosis in a geriatric patient with renal disease.
Topics: Aged; Amantadine; Female; Humans; Kidney Failure, Chronic; Parkinson Disease; Psychoses, Substance-I | 1979 |
Removal of amantadine hydrochloride by dialysis in patients with renal insufficiency.
Topics: Aged; Amantadine; Humans; Kidney Failure, Chronic; Male; Parkinson Disease; Peritoneal Dialysis; Ren | 1976 |
Letter: Accumulation of amantadine hydrochloride in renal insufficiency.
Topics: Adult; Amantadine; Humans; Kidney Failure, Chronic | 1974 |
Amantadine toxicity in a patient with renal insufficiency.
Topics: Amantadine; Dose-Response Relationship, Drug; Female; Humans; Influenza, Human; Kidney Failure, Chro | 1974 |