amantadine has been researched along with Chronic Hepatitis B in 4 studies
amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source
| Excerpt | Relevance | Reference |
|---|---|---|
| " Combination therapy with Interferon-α and ribavirin remains the backbone treatment for chronic hepatitis C; the addition of serine protease inhibitors improves the treatment outcome of patients infected with hepatitis C virus genotype 1." | 4.87 | Antiviral drugs for viruses other than human immunodeficiency virus. ( Razonable, RR, 2011) |
| "The study population consisted of 53 HBsAg-negative patients with chronic hepatitis C treated with IFN/ribavirin or IFN/ribavirin/amantadine." | 3.73 | Analysis of HCV co-infection with occult hepatitis B virus in patients undergoing IFN therapy. ( Chemin, I; Guillaud, O; Khattab, E; Mrani, S; Trepo, C; Vieux, C; Vuillermoz, I; Zoulim, F, 2005) |
| "Treatment of patients with chronic hepatitis B (CHB) with nucleos(t)ide analogues (NAs) suppresses hepatitis B virus (HBV) DNA production but does not affect the synthesis of the RNA pregenome or HBV messenger RNA." | 2.82 | Hepatitis B Virus Pregenomic RNA Is Present in Virions in Plasma and Is Associated With a Response to Pegylated Interferon Alfa-2a and Nucleos(t)ide Analogues. ( Jansen, L; Kootstra, NA; Reesink, HW; Takkenberg, RB; van Dort, KA; Zaaijer, HL, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jansen, L | 1 |
| Kootstra, NA | 1 |
| van Dort, KA | 1 |
| Takkenberg, RB | 1 |
| Reesink, HW | 1 |
| Zaaijer, HL | 1 |
| Razonable, RR | 1 |
| Khattab, E | 1 |
| Chemin, I | 1 |
| Vuillermoz, I | 1 |
| Vieux, C | 1 |
| Mrani, S | 1 |
| Guillaud, O | 1 |
| Trepo, C | 1 |
| Zoulim, F | 1 |
| Friedrich-Rust, M | 1 |
| Forestier, N | 1 |
| Zeuzem, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Predictive Value of HBV pgRNA on Long-term Outcomes in Hepatitis B Patients Treated With Antiviral Therapy[NCT05965388] | 5,000 participants (Anticipated) | Observational | 2023-12-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for amantadine and Chronic Hepatitis B
| Article | Year |
|---|---|
Antiviral drugs for viruses other than human immunodeficiency virus.
Topics: Acyclovir; Adenine; Amantadine; Antiviral Agents; Comorbidity; Drug Therapy, Combination; Foscarnet; | 2011 |
1 trial available for amantadine and Chronic Hepatitis B
| Article | Year |
|---|---|
Hepatitis B Virus Pregenomic RNA Is Present in Virions in Plasma and Is Associated With a Response to Pegylated Interferon Alfa-2a and Nucleos(t)ide Analogues.
Topics: Adenine; Adult; Amantadine; Antiviral Agents; Biomarkers; DNA, Viral; Drug Therapy, Combination; Fem | 2016 |
2 other studies available for amantadine and Chronic Hepatitis B
| Article | Year |
|---|---|
Analysis of HCV co-infection with occult hepatitis B virus in patients undergoing IFN therapy.
Topics: Adult; Amantadine; Amino Acid Sequence; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female | 2005 |
[Perspectives in hepatology in the next 2-3 years: what will be clinically relevant? Viral hepatitis].
Topics: Amantadine; Antiviral Agents; Genotype; Hepatitis B, Chronic; Hepatitis C, Chronic; Hepatovirus; Hum | 2005 |