amantadine has been researched along with Chronic Disease in 33 studies
amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| " In more than 50 percent of the cases of initial tremor induced by lithium therapy, oxprenolol in daily doses of 160--240 mg produced good effects and moderate improvement was noted in a few further cases." | 9.04 | Therapy of extrapyramidal side effects, with particular reference to persistent dyskinesia and lithium tremor. ( Pöldinger, W, 1978) |
| "Amantadinesulfate is a well known substance which has proven useful in the treatment and prophylaxis of viral infections, in treating symptoms of Parkinson's disease, cocaine dependence, and apathy in multiple sclerosis." | 6.69 | Amantadine revisited: an open trial of amantadinesulfate treatment in chronically depressed patients with Borna disease virus infection. ( Beelitz, G; Berghöfer, A; Bode, L; Brodhun, B; Ferszt, R; Kühl, KP; Ludwig, H; Müller-Oerlinghausen, B; Severus, EW; Winzer, B, 1999) |
| " In more than 50 percent of the cases of initial tremor induced by lithium therapy, oxprenolol in daily doses of 160--240 mg produced good effects and moderate improvement was noted in a few further cases." | 5.04 | Therapy of extrapyramidal side effects, with particular reference to persistent dyskinesia and lithium tremor. ( Pöldinger, W, 1978) |
| " We included studies investigating pemoline and modafinil in participants with multiple sclerosis (MS)-associated fatigue and methylphenidate in patients suffering from advanced cancer and fatigue in meta-analysis." | 4.91 | Pharmacological treatments for fatigue associated with palliative care. ( Cuhls, H; Minton, O; Mücke, M; Peuckmann-Post, V; Radbruch, L; Stone, P, 2015) |
| "Amantadinesulfate is a well known substance which has proven useful in the treatment and prophylaxis of viral infections, in treating symptoms of Parkinson's disease, cocaine dependence, and apathy in multiple sclerosis." | 2.69 | Amantadine revisited: an open trial of amantadinesulfate treatment in chronically depressed patients with Borna disease virus infection. ( Beelitz, G; Berghöfer, A; Bode, L; Brodhun, B; Ferszt, R; Kühl, KP; Ludwig, H; Müller-Oerlinghausen, B; Severus, EW; Winzer, B, 1999) |
| "Evidence on the treatment of tardive akathisia is unsatisfactory." | 2.41 | Managing antipsychotic-induced acute and chronic akathisia. ( Fleischhacker, WW; Miller, CH, 2000) |
| "We report a 48-year-old woman with a 17-year history of PD who developed a peripheral sensory-motor neuropathy secondary to chronic administration (8 years) of amantadine." | 1.30 | Amantadine-induced peripheral neuropathy. ( Minagar, A; Sharma, K; Shulman, LM; Weiner, WJ, 1999) |
| "Amantadine prophylaxis was performed in 91 patients during influenza A epidemics." | 1.29 | [Amantadine in the prevention of nosocomial influenza]. ( Bíró, L; Guller, Z; Koltai, M; Szepesi, A, 1996) |
| "Twenty patients with idiopathic Parkinson's disease (PD) and motor fluctuations received open-label amantadine (100-200 mg/d) in addition to their other antiparkinson medications." | 1.27 | Amantadine and motor fluctuations in chronic Parkinson's disease. ( Carroll, VS; Goetz, CG; Klawans, HL; Shannon, KM; Tanner, CM, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (33.33) | 18.7374 |
| 1990's | 11 (33.33) | 18.2507 |
| 2000's | 6 (18.18) | 29.6817 |
| 2010's | 4 (12.12) | 24.3611 |
| 2020's | 1 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Carlson, JM | 1 |
| Lin, DJ | 1 |
| Madden, M | 1 |
| Gurney, M | 1 |
| Bright, S | 1 |
| Mücke, M | 1 |
| Cuhls, H | 1 |
| Peuckmann-Post, V | 1 |
| Minton, O | 1 |
| Stone, P | 1 |
| Radbruch, L | 1 |
| Vonder Haar, C | 1 |
| Lam, FC | 1 |
| Adams, WK | 1 |
| Riparip, LK | 1 |
| Kaur, S | 1 |
| Muthukrishna, M | 1 |
| Rosi, S | 1 |
| Winstanley, CA | 1 |
| Oliveira, L | 1 |
| Fregni, F | 1 |
| Vrolijk, JM | 1 |
| de Knegt, RJ | 1 |
| Veldt, BJ | 1 |
| Orlent, H | 1 |
| Schalm, SW | 1 |
| Kleinböhl, D | 1 |
| Görtelmeyer, R | 1 |
| Bender, HJ | 1 |
| Hölzl, R | 1 |
| Boërio, D | 1 |
| Lefaucheur, JP | 1 |
| Hogrel, JY | 1 |
| Créange, A | 1 |
| Wenger, C | 1 |
| Bischof, T | 1 |
| Gonvers, JJ | 1 |
| Renner, EL | 1 |
| Mullhaupt, B | 1 |
| Wu, MJ | 1 |
| Daugirdas, JT | 1 |
| Ing, TS | 1 |
| Silver, H | 2 |
| Geraisy, N | 2 |
| Bíró, L | 1 |
| Guller, Z | 1 |
| Koltai, M | 1 |
| Szepesi, A | 1 |
| Yamada, K | 1 |
| Kanba, S | 1 |
| Ohnishi, K | 1 |
| Ashikari, I | 1 |
| Yagi, G | 1 |
| Asai, M | 1 |
| Kraus, MF | 1 |
| Maki, P | 1 |
| Levine, J | 1 |
| Martine, T | 1 |
| Feraro, R | 1 |
| Kimhi, R | 1 |
| Bracha, HS | 1 |
| Smith, JP | 1 |
| Eisenberg, E | 1 |
| Pud, D | 1 |
| Ferszt, R | 1 |
| Kühl, KP | 1 |
| Bode, L | 1 |
| Severus, EW | 1 |
| Winzer, B | 1 |
| Berghöfer, A | 1 |
| Beelitz, G | 1 |
| Brodhun, B | 1 |
| Müller-Oerlinghausen, B | 1 |
| Ludwig, H | 1 |
| Shulman, LM | 1 |
| Minagar, A | 1 |
| Sharma, K | 1 |
| Weiner, WJ | 1 |
| Miller, CH | 1 |
| Fleischhacker, WW | 1 |
| Koczorek, M | 1 |
| Pöldinger, W | 1 |
| Kamenetskiĭ, VK | 1 |
| Lindenmayer, JP | 1 |
| Vakharia, M | 1 |
| Kanofsky, D | 1 |
| McEvoy, JP | 1 |
| McCue, M | 1 |
| Freter, S | 1 |
| Shannon, KM | 1 |
| Goetz, CG | 1 |
| Carroll, VS | 1 |
| Tanner, CM | 1 |
| Klawans, HL | 1 |
| Bauer, DJ | 1 |
| Man'kovskii, NB | 1 |
| Vainshtok, AB | 1 |
| Oleinik, LI | 1 |
| Kiseleva, AM | 1 |
| Zlydnikov, DM | 1 |
| Mazhinskaia, VP | 1 |
| Lebedeva, VK | 1 |
| Zakharova, NG | 1 |
| Morgan, L | 1 |
| Gessler, U | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Feasibility Study of Adjunctive Bright Light Therapy (BLT) for Amelioration of Fatigue in Chinese Cancer Patients Admitted to a Palliative Care Unit[NCT04525924] | 42 participants (Anticipated) | Interventional | 2020-08-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for amantadine and Chronic Disease
| Article | Year |
|---|---|
Pharmacological treatments for fatigue associated with palliative care.
Topics: Adult; Amantadine; Benzhydryl Compounds; Carnitine; Central Nervous System Stimulants; Chronic Disea | 2015 |
Pharmacological and electrical stimulation in chronic disorders of consciousness: new insights and future directions.
Topics: Amantadine; Chronic Disease; Combined Modality Therapy; Deep Brain Stimulation; Dopamine Agents; Hum | 2011 |
The treatment of hepatitis C: history, presence and future.
Topics: Amantadine; Antiviral Agents; Chronic Disease; Consensus; Drug Therapy, Combination; Hepatitis C; Hu | 2004 |
[Pathophysiology and treatment of fatigue in multiple sclerosis].
Topics: 4-Aminopyridine; Acute Disease; Amantadine; Amifampridine; Asthenia; Benzhydryl Compounds; Central N | 2006 |
Managing antipsychotic-induced acute and chronic akathisia.
Topics: Acute Disease; Akathisia, Drug-Induced; Amantadine; Antipsychotic Agents; Benzodiazepines; Cholinerg | 2000 |
Antiviral chemotherapy: the first decade.
Topics: Acute Disease; Amantadine; Antiviral Agents; Chickenpox; Chronic Disease; Cytarabine; Herpes Simplex | 1973 |
9 trials available for amantadine and Chronic Disease
| Article | Year |
|---|---|
Amantadine sulfate reduces experimental sensitization and pain in chronic back pain patients.
Topics: Adult; Aged; Amantadine; Back Pain; Chronic Disease; Double-Blind Method; Hot Temperature; Humans; M | 2006 |
Interferon and ribavirin with or without amantadine for interferon non-responders with chronic hepatitis C. A randomized, controlled pilot study.
Topics: Adolescent; Adult; Aged; Amantadine; Chronic Disease; Drug Therapy, Combination; Female; Hepatitis C | 2007 |
No difference in the effect of biperiden and amantadine on negative symptoms in medicated chronic schizophrenic patients.
Topics: Adult; Amantadine; Basal Ganglia Diseases; Biperiden; Chronic Disease; Cross-Over Studies; Dopamine | 1995 |
Amantadine does not exacerbate positive symptoms in medicated, chronic schizophrenic patients: evidence from a double-blind crossover study.
Topics: Adult; Amantadine; Antiparkinson Agents; Chronic Disease; Double-Blind Method; Female; Humans; Male; | 1996 |
Treatment of chronic hepatitis C with amantadine.
Topics: Adolescent; Aged; Alanine Transaminase; Amantadine; Antiviral Agents; Chronic Disease; Female; Hepac | 1997 |
Amantadine revisited: an open trial of amantadinesulfate treatment in chronically depressed patients with Borna disease virus infection.
Topics: Amantadine; Analysis of Variance; Antidepressive Agents; Antiviral Agents; Borna Disease; Chronic Di | 1999 |
Therapy of extrapyramidal side effects, with particular reference to persistent dyskinesia and lithium tremor.
Topics: Adolescent; Adult; Amantadine; Antipsychotic Agents; Basal Ganglia Diseases; Bromocriptine; Chronic | 1978 |
Replacement of chronically administered anticholinergic drugs by amantadine in outpatient management of chronic schizophrenia.
Topics: Adult; Amantadine; Antipsychotic Agents; Benztropine; Chronic Disease; Dyskinesia, Drug-Induced; Fem | 1987 |
[The therapeutic effectiveness of amantadine (midantan) in parkinsonism syndromes].
Topics: Adult; Aged; Amantadine; Chronic Disease; Female; Humans; Male; Middle Aged; Parasympatholytics; Par | 1973 |
18 other studies available for amantadine and Chronic Disease
| Article | Year |
|---|---|
Prognostication in Prolonged and Chronic Disorders of Consciousness.
Topics: Amantadine; Chronic Disease; Consciousness; Consciousness Disorders; Electroencephalography; Humans; | 2023 |
Amantadine, an N-Methyl-D-Aspartate antagonist, for treatment of chronic neuropathic pain in a dog.
Topics: Amantadine; Analgesics, Non-Narcotic; Animals; Chronic Disease; Dog Diseases; Dogs; Female; Neuralgi | 2014 |
Frontal Traumatic Brain Injury in Rats Causes Long-Lasting Impairments in Impulse Control That Are Differentially Sensitive to Pharmacotherapeutics and Associated with Chronic Neuroinflammation.
Topics: Acute Disease; Adrenergic Uptake Inhibitors; Amantadine; Amphetamine; Animals; Atomoxetine Hydrochlo | 2016 |
Prevention and control of influenza.
Topics: Adult; Aged; Amantadine; Child; Child, Preschool; Chronic Disease; Disease Outbreaks; Female; Humans | 1984 |
Preventing influenza in chronic renal disease.
Topics: Amantadine; Child; Chronic Disease; Humans; Influenza Vaccines; Influenza, Human; Kidney Diseases; V | 1981 |
[Amantadine in the prevention of nosocomial influenza].
Topics: Aged; Amantadine; Antiviral Agents; Cardiovascular Diseases; Chronic Disease; Cross Infection; Diabe | 1996 |
Changes in symptoms and plasma homovanillic acid with amantadine hydrochloride in chronic schizophrenia.
Topics: Adult; Aged; Amantadine; Chronic Disease; Dopamine Agents; Dose-Response Relationship, Drug; Drug Ad | 1997 |
The combined use of amantadine and l-dopa/carbidopa in the treatment of chronic brain injury.
Topics: Amantadine; Behavior; Brain Injuries; Carbidopa; Chronic Disease; Cognition; Drug Therapy, Combinati | 1997 |
Medicated chronic schizophrenic patients do not demonstrate left turning asymmetry.
Topics: Adult; Amantadine; Antipsychotic Agents; Chronic Disease; Dominance, Cerebral; Dopamine Agents; Fema | 1997 |
Can patients with chronic neuropathic pain be cured by acute administration of the NMDA receptor antagonist amantadine?
Topics: Aged; Amantadine; Analgesics, Non-Narcotic; Chronic Disease; Excitatory Amino Acid Antagonists; Fema | 1998 |
Amantadine-induced peripheral neuropathy.
Topics: Amantadine; Antiparkinson Agents; Chronic Disease; Female; Humans; Leg; Middle Aged; Muscle Weakness | 1999 |
[Chronic liver diseases. The nihilism has gone].
Topics: Amantadine; Antioxidants; Antiviral Agents; Chronic Disease; Dipeptides; Drug Therapy, Combination; | 2001 |
[Combined use of metamizil and midantan in vascular parkinsonism].
Topics: Aged; Amantadine; Benactyzine; Chronic Disease; Drug Evaluation; Drug Therapy, Combination; Humans; | 1979 |
Fluoxetine in chronic schizophrenia.
Topics: Amantadine; Chronic Disease; Drug Therapy, Combination; Fluoxetine; Humans; Loxapine; Male; Middle A | 1990 |
Amantadine and motor fluctuations in chronic Parkinson's disease.
Topics: Adult; Aged; Amantadine; Chronic Disease; Female; Humans; Male; Middle Aged; Movement Disorders; Par | 1987 |
[Experience in the prolonged use of midantan (amantadine hydrochloride) in parkinsonism].
Topics: Administration, Oral; Adult; Aged; Amantadine; Chronic Disease; Electromyography; Epinephrine; Femal | 1973 |
Amantadine in the treatment of advanced Parkinsonism.
Topics: Amantadine; Chronic Disease; Humans; Parkinson Disease | 1970 |
[On the effect of 1-aminoadamantane hydrochloride on the kidney function].
Topics: Adult; Amantadine; Chronic Disease; Creatinine; Glomerulonephritis; Humans; Kidney; Male; Pyelonephr | 1968 |