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amantadine and Chemical Dependence

amantadine has been researched along with Chemical Dependence in 25 studies

amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source

Research Excerpts

ExcerptRelevanceReference
"Amantadine was well tolerated."2.68Amantadine does not reduce cocaine use or craving in cocaine-dependent methadone maintenance patients. ( Handelsman, L; Limpitlaw, L; Paris, P; Schmeidler, J; Stimmel, B; Williams, D, 1995)
"Thus, antisocial personality disorder was a poor prognostic factor for treatment retention and continued cocaine abuse, and medication did not improve treatment outcome for the ASP patients, but did for the non-ASP patients."2.67Antisocial personality disorder as a prognostic factor for pharmacotherapy of cocaine dependence. ( Kosten, T; Leal, J; Ziedonis, D, 1994)
" Mean plasma concentration of desipramine in a subsample of our subjects was less than that recommended for treatment of depression, thus the dosage of desipramine may have been subtherapeutic."2.67Comparison of amantadine and desipramine combined with psychotherapy for treatment of cocaine dependence. ( Brown, BS; Haertzen, CA; Hess, JM; Jaffe, JH; Kolar, AF; Mahaffey, JR; Weddington, WW, 1991)
"Informing drug abusers in treatment regarding positive HIV-serostatus was not associated with a lower treatment-retention rate or adverse psychological reactions when counseling regarding HIV issues was integrated with drug abuse treatment."2.67Psychological reactions and retention by cocaine addicts during treatment according to HIV-serostatus: a matched-control study. ( Brown, BS; Haertzen, CA; Hess, JM; Weddington, WW, 1991)
"Bromocriptine was significantly more effective than both throughout the latter phase of the study."2.66Bromocriptine and amantadine in cocaine detoxification. ( Feather, JN; Folts, DJ; Giannini, AJ; Sullivan, BS, 1989)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19909 (36.00)18.7374
1990's13 (52.00)18.2507
2000's2 (8.00)29.6817
2010's0 (0.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Revol, B1
Lapeyre-Mestre, M1
Fouilhé Sam-Laï, N1
Jouanjus, E1
Kornhuber, J1
Weller, M1
Schoppmeyer, K1
Riederer, P1
Leal, J1
Ziedonis, D1
Kosten, T1
Handelsman, L2
Limpitlaw, L1
Williams, D1
Schmeidler, J1
Paris, P1
Stimmel, B1
Pálfi, S1
Ungureán, A1
Vécsei, L1
Sunohara, N1
Deleu, D1
Hanssens, Y1
Kolar, AF3
Brown, BS4
Weddington, WW4
Haertzen, CC1
Michaelson, BS1
Jaffe, JH2
Alterman, AI1
Droba, M1
Antelo, RE1
Cornish, JW1
Sweeney, KK1
Parikh, GA1
O'Brien, CP1
Kosten, TR4
Morgan, CM1
Falcione, J1
Schottenfeld, RS2
Ziedonis, DM1
Haertzen, CA3
Hess, JM3
Mahaffey, JR2
Morgan, CH1
Taylor, WA1
Gold, MS1
Gawin, FH1
Morgan, C1
Kleber, HD1
Giannini, AJ1
Folts, DJ1
Feather, JN1
Sullivan, BS1
Tennant, F2
Shannon, J1
Harvey, NS1
Pike, RF1
Chordia, PL1
Escovar, IL1
Marion, IJ1
Lowinson, JH1
Berman, ML1

Reviews

5 reviews available for amantadine and Chemical Dependence

ArticleYear
Consensus conference. Treatment of hepatitis C.
    Gastroenterologie clinique et biologique, 2002, Volume: 26 Spec No 2

    Topics: Adult; Aged; Alcoholism; Amantadine; Antiviral Agents; Body Weight; Child; Drug Therapy, Combination

2002
Amantadine and memantine are NMDA receptor antagonists with neuroprotective properties.
    Journal of neural transmission. Supplementum, 1994, Volume: 43

    Topics: Adamantane; Amantadine; Animals; Behavior, Animal; Dopamine; Electrophysiology; Hallucinogens; Human

1994
[Toxic and adverse neurological effects of anti-parkinsonian drugs].
    Ryoikibetsu shokogun shirizu, 1999, Issue:27 Pt 2

    Topics: Amantadine; Antiparkinson Agents; Bromocriptine; Cholinergic Antagonists; Dopamine Agents; Dyskinesi

1999
Pharmacologic approaches to the treatment of cocaine dependence.
    The Western journal of medicine, 1990, Volume: 152, Issue:5

    Topics: Amantadine; Antidepressive Agents, Tricyclic; Bromocriptine; Cocaine; Dopamine Agents; Humans; Subst

1990
Psychiatric disorders in parkinsonism: 2. Organic cerebral states and drug reactions.
    Psychosomatics, 1986, Volume: 27, Issue:3

    Topics: Amantadine; Antiparkinson Agents; Atrophy; Brain; Bromocriptine; Cognition; Dementia; Dreams; Drug I

1986

Trials

12 trials available for amantadine and Chemical Dependence

ArticleYear
Antisocial personality disorder as a prognostic factor for pharmacotherapy of cocaine dependence.
    Drug and alcohol dependence, 1994, Volume: 35, Issue:1

    Topics: Adult; Amantadine; Antisocial Personality Disorder; Cocaine; Combined Modality Therapy; Comorbidity;

1994
Amantadine does not reduce cocaine use or craving in cocaine-dependent methadone maintenance patients.
    Drug and alcohol dependence, 1995, Volume: 39, Issue:3

    Topics: Adult; Amantadine; Cocaine; Dopamine Agonists; Dose-Response Relationship, Drug; Double-Blind Method

1995
Treatment of cocaine dependence in methadone maintenance clients: a pilot study comparing the efficacy of desipramine and amantadine.
    The International journal of the addictions, 1992, Volume: 27, Issue:7

    Topics: Adolescent; Adult; Amantadine; Baltimore; Cocaine; Desipramine; Female; Follow-Up Studies; Humans; M

1992
Amantadine may facilitate detoxification of cocaine addicts.
    Drug and alcohol dependence, 1992, Volume: 31, Issue:1

    Topics: Adult; Amantadine; Cocaine; Day Care, Medical; Double-Blind Method; Follow-Up Studies; Humans; Male;

1992
Pharmacotherapy for cocaine-abusing methadone-maintained patients using amantadine or desipramine.
    Archives of general psychiatry, 1992, Volume: 49, Issue:11

    Topics: Adult; Amantadine; Cocaine; Desipramine; Double-Blind Method; Female; Humans; Male; Methadone; Opioi

1992
Depression as a prognostic factor for pharmacological treatment of cocaine dependence.
    Psychopharmacology bulletin, 1991, Volume: 27, Issue:3

    Topics: Adult; Amantadine; Cocaine; Depression; Desipramine; Female; Humans; Male; Prognosis; Psychiatric St

1991
Comparison of amantadine and desipramine combined with psychotherapy for treatment of cocaine dependence.
    The American journal of drug and alcohol abuse, 1991, Volume: 17, Issue:2

    Topics: Adult; Amantadine; Cocaine; Combined Modality Therapy; Desipramine; Dose-Response Relationship, Drug

1991
Amantadine and desipramine in the treatment of cocaine abusing methadone maintained patients.
    NIDA research monograph, 1990, Volume: 105

    Topics: Adult; Amantadine; Cocaine; Desipramine; Double-Blind Method; Female; Humans; Male; Methadone; Opioi

1990
Psychological reactions and retention by cocaine addicts during treatment according to HIV-serostatus: a matched-control study.
    The American journal of drug and alcohol abuse, 1991, Volume: 17, Issue:3

    Topics: Adaptation, Psychological; Adult; Affect; AIDS Serodiagnosis; Amantadine; Baltimore; Cocaine; Combin

1991
Double-blind evaluation of the effect of acute amantadine on cocaine craving.
    Psychopharmacology, 1989, Volume: 97, Issue:3

    Topics: Amantadine; Cocaine; Double-Blind Method; Humans; Substance-Related Disorders

1989
Bromocriptine and amantadine in cocaine detoxification.
    Psychiatry research, 1989, Volume: 29, Issue:1

    Topics: Adult; Amantadine; Brain; Bromocriptine; Clinical Trials as Topic; Cocaine; Humans; Male; Random All

1989
Comparison of amantadine and desipramine combined with psychotherapy for treatment of cocaine dependence.
    NIDA research monograph, 1989, Volume: 95

    Topics: Amantadine; Clinical Trials as Topic; Cocaine; Combined Modality Therapy; Desipramine; Follow-Up Stu

1989

Other Studies

8 other studies available for amantadine and Chemical Dependence

ArticleYear
Association between NMDAR antagonists, drug abuse and dependence: A disproportionality analysis from the WHO pharmacovigilance database.
    British journal of clinical pharmacology, 2022, Volume: 88, Issue:11

    Topics: Amantadine; Analgesics; Bayes Theorem; Dextromethorphan; Humans; Ketamine; Memantine; Pharmacovigila

2022
Basilar artery occlusion associated with anabolic steroid abuse in a 17-year-old bodybuilder.
    European neurology, 1997, Volume: 37, Issue:3

    Topics: Adolescent; Amantadine; Anabolic Agents; Arterial Occlusive Diseases; Basilar Artery; Cerebral Angio

1997
Cerebellar dysfunction in chronic toluene abuse: beneficial response to amantadine hydrochloride.
    Journal of toxicology. Clinical toxicology, 2000, Volume: 38, Issue:1

    Topics: Adult; Amantadine; Cerebellar Diseases; Dopamine Agents; Humans; Magnetic Resonance Imaging; Male; S

2000
Quantitative urine testing. A new tool for diagnosing and treating cocaine use.
    Postgraduate medicine, 1989, Sep-01, Volume: 86, Issue:3

    Topics: Adolescent; Adult; Amantadine; Amino Acids; Cocaine; Female; Humans; Levodopa; Male; Radioimmunoassa

1989
Cocaine withdrawal. An effective three-drug regimen.
    Postgraduate medicine, 1989, Volume: 85, Issue:4

    Topics: Amantadine; Cocaine; Humans; Lorazepam; Substance Withdrawal Syndrome; Substance-Related Disorders;

1989
Amantadine for treatment of cocaine dependence in methadone-maintained patients.
    The American journal of psychiatry, 1988, Volume: 145, Issue:4

    Topics: Adult; Amantadine; Cocaine; Female; Humans; Male; Methadone; Middle Aged; Opioid-Related Disorders;

1988
Stepwise detoxification from cocaine. A promising regimen.
    Postgraduate medicine, 1988, Volume: 84, Issue:2

    Topics: Adolescent; Adult; Amantadine; Bromocriptine; Cocaine; Desipramine; Drug Therapy, Combination; Femal

1988
Concurrent session: current trends in neurology and psychiatry.
    The Medical journal of Australia, 1971, Oct-02, Volume: 2, Issue:14

    Topics: Amantadine; Behavior Therapy; Dihydroxyphenylalanine; Epilepsy; Female; Humans; Male; Neurology; Par

1971