Page last updated: 2024-10-22

amantadine and Charcot-Marie-Tooth Disease

amantadine has been researched along with Charcot-Marie-Tooth Disease in 1 studies

amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source

Charcot-Marie-Tooth Disease: A hereditary motor and sensory neuropathy transmitted most often as an autosomal dominant trait and characterized by progressive distal wasting and loss of reflexes in the muscles of the legs (and occasionally involving the arms). Onset is usually in the second to fourth decade of life. This condition has been divided into two subtypes, hereditary motor and sensory neuropathy (HMSN) types I and II. HMSN I is associated with abnormal nerve conduction velocities and nerve hypertrophy, features not seen in HMSN II. (Adams et al., Principles of Neurology, 6th ed, p1343)

Research Excerpts

ExcerptRelevanceReference
" The effects of amantadine from one randomised, double-blind, placebo-controlled, cross-over trial comparing amantadine with placebo for the treatment of fatigue in 80 people with Guillain-Barré syndrome (GBS) were uncertain for the proportion of people achieving a favourable outcome six weeks post-intervention (odds ratio (OR) 0."4.90Interventions for fatigue in peripheral neuropathy. ( Garssen, MP; Stockley, RC; van Doorn, PA; White, CM, 2014)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
White, CM1
van Doorn, PA1
Garssen, MP1
Stockley, RC1

Reviews

1 review available for amantadine and Charcot-Marie-Tooth Disease

ArticleYear
Interventions for fatigue in peripheral neuropathy.
    The Cochrane database of systematic reviews, 2014, Dec-18, Issue:12

    Topics: Adult; Amantadine; Ascorbic Acid; Charcot-Marie-Tooth Disease; Child; Fatigue; Guillain-Barre Syndro

2014