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amantadine and Borna Disease

amantadine has been researched along with Borna Disease in 15 studies

amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source

Borna Disease: An encephalomyelitis of horses, sheep and cattle caused by BORNA DISEASE VIRUS.

Research Excerpts

ExcerptRelevanceReference
"Successful inhibition of Borna disease virus (BDV) by amantadine in cultured cells and in an infected human individual has been reported [Bode et al."7.69Borna disease virus is not sensitive to amantadine. ( Hallensleben, W; Staeheli, P; Zocher, M, 1997)
"Amantadinesulfate is a well known substance which has proven useful in the treatment and prophylaxis of viral infections, in treating symptoms of Parkinson's disease, cocaine dependence, and apathy in multiple sclerosis."6.69Amantadine revisited: an open trial of amantadinesulfate treatment in chronically depressed patients with Borna disease virus infection. ( Beelitz, G; Berghöfer, A; Bode, L; Brodhun, B; Ferszt, R; Kühl, KP; Ludwig, H; Müller-Oerlinghausen, B; Severus, EW; Winzer, B, 1999)
"Amantadine was given twice a day (100-300 mg/day) for a mean of 11 weeks."6.69Amantadine in depressive patients with Borna disease virus (BDV) infection: an open trial. ( Bode, L; Brodhun, B; Dietrich, DE; Emrich, HM; Huber, TJ; Lau, T; Ludwig, H; Spannhuth, CW, 2000)
"The interventional phase II RCT (two 7-weeks-treatment periods and a 12-months follow-up) at the Hannover Medical School (MHH), Germany, assigned currently depressed BDV-1 infected patients with either major depression (MD; N = 23) or bipolar disorder (BD; N = 13) to amantadine sulphate (PK-Merz®; twice 100 mg orally daily) or placebo treatment, and contrariwise, respectively."5.34Antiviral treatment perspective against Borna disease virus 1 infection in major depression: a double-blind placebo-controlled randomized clinical trial. ( Bode, L; Dietrich, DE; Emrich, HM; Hecker, H; Ludwig, H; Spannhuth, CW, 2020)
"Amantadinesulfate is a well known substance which has proven useful in the treatment and prophylaxis of viral infections, in treating symptoms of Parkinson's disease, cocaine dependence, and apathy in multiple sclerosis."2.69Amantadine revisited: an open trial of amantadinesulfate treatment in chronically depressed patients with Borna disease virus infection. ( Beelitz, G; Berghöfer, A; Bode, L; Brodhun, B; Ferszt, R; Kühl, KP; Ludwig, H; Müller-Oerlinghausen, B; Severus, EW; Winzer, B, 1999)
"Amantadine treatment was used as an antidepressant and antiviral compound."2.69Word recognition memory before and after successful treatment of depression. ( Dietrich, DE; Emrich, HM; Hauser, U; Huber, TJ; Johannes, S; Kipp, K; Kleinschmidt, A; Schneider, U; Spannhuth, CW; Wieringa, BM, 2000)
"Amantadine was given twice a day (100-300 mg/day) for a mean of 11 weeks."2.69Amantadine in depressive patients with Borna disease virus (BDV) infection: an open trial. ( Bode, L; Brodhun, B; Dietrich, DE; Emrich, HM; Huber, TJ; Lau, T; Ludwig, H; Spannhuth, CW, 2000)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (33.33)18.2507
2000's9 (60.00)29.6817
2010's0 (0.00)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Dietrich, DE6
Bode, L6
Spannhuth, CW3
Hecker, H1
Ludwig, H5
Emrich, HM5
Ohlmeier, MD1
Zhang, Y1
Sieg, S1
Feutl, S1
Dieckhöfer, R1
Merkt, JC1
Weber, R1
Kamitani, W1
Tomonaga, K1
Ikuta, K1
Stoyloff, R1
Hallensleben, W1
Zocher, M1
Staeheli, P2
Stitz, L1
Planz, O1
Bilzer, T1
Schwemmle, M1
Ferszt, R1
Kühl, KP1
Severus, EW1
Winzer, B1
Berghöfer, A1
Beelitz, G1
Brodhun, B2
Müller-Oerlinghausen, B1
Kleinschmidt, A1
Hauser, U1
Schneider, U1
Kipp, K1
Huber, TJ2
Wieringa, BM1
Johannes, S1
Lau, T1
Lieb, K1

Reviews

3 reviews available for amantadine and Borna Disease

ArticleYear
Human Borna disease virus-infection and its therapy in affective disorders.
    APMIS. Supplementum, 2008, Issue:124

    Topics: Amantadine; Antiviral Agents; Borna Disease; Borna disease virus; Clinical Trials as Topic; Depressi

2008
[Borna disease virus infection].
    Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 2

    Topics: Amantadine; Animals; Antibodies, Viral; Antiviral Agents; Borna Disease; Borna disease virus; Brain;

2003
Borna disease virus--does it infect humans and cause psychiatric disorders?
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2001, Volume: 21, Issue:2

    Topics: Amantadine; Animals; Antibodies, Viral; Antiviral Agents; Borna Disease; Borna disease virus; Brain;

2001

Trials

6 trials available for amantadine and Borna Disease

ArticleYear
Antiviral treatment perspective against Borna disease virus 1 infection in major depression: a double-blind placebo-controlled randomized clinical trial.
    BMC pharmacology & toxicology, 2020, 02-17, Volume: 21, Issue:1

    Topics: Adult; Amantadine; Animals; Antibodies, Viral; Antidepressive Agents; Antigens, Viral; Antiviral Age

2020
Amantadine reduces mania in borna disease virus-infected non-psychotic bipolar patients.
    Pharmacopsychiatry, 2008, Volume: 41, Issue:5

    Topics: Aged; Amantadine; Antiviral Agents; Bipolar Disorder; Borna Disease; Female; Humans; Male; Middle Ag

2008
Infections in horses: diagnosis and therapy.
    APMIS. Supplementum, 2008, Issue:124

    Topics: Amantadine; Animals; Antibodies, Viral; Antigen-Antibody Complex; Antigens, Viral; Antiviral Agents;

2008
Amantadine revisited: an open trial of amantadinesulfate treatment in chronically depressed patients with Borna disease virus infection.
    Pharmacopsychiatry, 1999, Volume: 32, Issue:4

    Topics: Amantadine; Analysis of Variance; Antidepressive Agents; Antiviral Agents; Borna Disease; Chronic Di

1999
Word recognition memory before and after successful treatment of depression.
    Pharmacopsychiatry, 2000, Volume: 33, Issue:6

    Topics: Adult; Aged; Amantadine; Antidepressive Agents; Antiviral Agents; Borna Disease; Cross-Over Studies;

2000
Amantadine in depressive patients with Borna disease virus (BDV) infection: an open trial.
    Bipolar disorders, 2000, Volume: 2, Issue:1

    Topics: Adult; Aged; Amantadine; Antidepressive Agents; Borna Disease; Depressive Disorder, Major; Female; H

2000

Other Studies

6 other studies available for amantadine and Borna Disease

ArticleYear
Horses diagnosed clinically and by laboratory methods for bornavirus infection and treated with amantadine: "patients" of the Tierärztliche Klinik für Pferde in Meerbusch. Case report.
    APMIS. Supplementum, 2008, Issue:124

    Topics: Amantadine; Animals; Antigen-Antibody Complex; Antigens, Viral; Borna Disease; Bornaviridae; Diagnos

2008
The history and treatment of a bipolar patient diagnosed with Borna disease virus infection. Case report.
    APMIS. Supplementum, 2008, Issue:124

    Topics: Adult; Amantadine; Antidepressive Agents; Bipolar Disorder; Borna Disease; Drug Administration Sched

2008
Amantadine and human Borna disease virus in vitro and in vivo in an infected patient with bipolar depression.
    Lancet (London, England), 1997, Jan-18, Volume: 349, Issue:9046

    Topics: Aged; Amantadine; Animals; Antiviral Agents; Bipolar Disorder; Borna Disease; Borna disease virus; F

1997
Borna disease virus is not sensitive to amantadine.
    Archives of virology, 1997, Volume: 142, Issue:10

    Topics: Amantadine; Animals; Antiviral Agents; Borna Disease; Borna disease virus; Brain; Chlorocebus aethio

1997
Lack of antiviral effect of amantadine in Borna disease virus infection.
    Medical microbiology and immunology, 1998, Volume: 186, Issue:4

    Topics: Administration, Oral; Amantadine; Animals; Antiviral Agents; Borna Disease; Borna disease virus; Bra

1998
Progress and controversy in Bornavirus research: a meeting report.
    Archives of virology, 1999, Volume: 144, Issue:4

    Topics: Amantadine; Animals; Antiviral Agents; Borna Disease; Borna disease virus; Brain; Cats; Dogs; Horse

1999