amantadine has been researched along with Ataxia Telangiectasia in 1 studies
amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source
Ataxia Telangiectasia: An autosomal recessive inherited disorder characterized by choreoathetosis beginning in childhood, progressive CEREBELLAR ATAXIA; TELANGIECTASIS of CONJUNCTIVA and SKIN; DYSARTHRIA; B- and T-cell immunodeficiency, and RADIOSENSITIVITY to IONIZING RADIATION. Affected individuals are prone to recurrent sinobronchopulmonary infections, lymphoreticular neoplasms, and other malignancies. Serum ALPHA-FETOPROTEINS are usually elevated. (Menkes, Textbook of Child Neurology, 5th ed, p688) The gene for this disorder (ATM) encodes a cell cycle checkpoint protein kinase and has been mapped to chromosome 11 (11q22-q23).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amantadine is a well-tolerated and effective treatment for motor symptoms in ataxia telangiectasia." | 2.78 | Movement disorder in ataxia-telangiectasia: treatment with amantadine sulfate. ( Ben-Zeev, B; Hassin-Baer, S; Lerman, SF; Levi, YB; Nissenkorn, A; Tzadok, M, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nissenkorn, A | 1 |
| Hassin-Baer, S | 1 |
| Lerman, SF | 1 |
| Levi, YB | 1 |
| Tzadok, M | 1 |
| Ben-Zeev, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Amantadine on Movement Disorder in Ataxia-Telangiectasia[NCT00950196] | Phase 4 | 30 participants (Anticipated) | Interventional | 2008-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for amantadine and Ataxia Telangiectasia
| Article | Year |
|---|---|
Movement disorder in ataxia-telangiectasia: treatment with amantadine sulfate.
Topics: Adolescent; Amantadine; Antiparkinson Agents; Ataxia Telangiectasia; Child; Child, Preschool; Disabi | 2013 |