Page last updated: 2024-10-22

amantadine and Apoplexy

amantadine has been researched along with Apoplexy in 9 studies

amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source

Research Excerpts

ExcerptRelevanceReference
"To assess the efficacy and safety of amantadine sulfate in patients with ischemic stroke."9.34[The use of amantadine sulfate in ischemic stroke]. ( Akhmatkhanova, LK; Kovaleva, EA; Ramazanov, GR; Shevchenko, EV, 2020)
"Amantadine and modafinil are neurostimulants that may improve cognitive and functional recovery post-stroke, but the existing study results vary, and no comprehensive review has been published."9.05Amantadine and Modafinil as Neurostimulants During Post-stroke Care: A Systematic Review. ( Brown, CS; Cote, J; Eldridge, A; Gagnon, DJ; Leclerc, AM; May, T; Nocella, K; Riker, RR; Seder, DB, 2020)
"To assess the efficacy and safety of amantadine sulfate in patients with ischemic stroke."5.34[The use of amantadine sulfate in ischemic stroke]. ( Akhmatkhanova, LK; Kovaleva, EA; Ramazanov, GR; Shevchenko, EV, 2020)
"Amantadine and modafinil are neurostimulants that may improve cognitive and functional recovery post-stroke, but the existing study results vary, and no comprehensive review has been published."5.05Amantadine and Modafinil as Neurostimulants During Post-stroke Care: A Systematic Review. ( Brown, CS; Cote, J; Eldridge, A; Gagnon, DJ; Leclerc, AM; May, T; Nocella, K; Riker, RR; Seder, DB, 2020)
"We pooled individual patient data of five single-centre observational studies to determine the effect of amantadine treatment among patients with ischaemic stroke, intracerebral haemorrhage, subarachnoid haemorrhage, community-acquired bacterial meningitis and status epilepticus, admitted between January 2012 and December 2015 and ventilated ≥7 days."4.12Amantadine treatment is associated with improved consciousness in patients with non-traumatic brain injury. ( Balk, S; Gerner, ST; Giede-Jeppe, A; Huttner, HB; Jäger, J; Kallmünzer, B; Kuramatsu, JB; Madzar, D; Mueller, T; Rühl, L; Schwab, S; Sembill, JA; Sprügel, MI, 2022)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (44.44)29.6817
2010's1 (11.11)24.3611
2020's4 (44.44)2.80

Authors

AuthorsStudies
Rühl, L1
Kuramatsu, JB1
Sembill, JA1
Kallmünzer, B1
Madzar, D1
Gerner, ST1
Giede-Jeppe, A1
Balk, S1
Mueller, T1
Jäger, J1
Schwab, S1
Huttner, HB1
Sprügel, MI1
Gagnon, DJ2
Leclerc, AM2
Riker, RR2
Brown, CS2
May, T2
Nocella, K2
Cote, J2
Eldridge, A2
Seder, DB2
Ramazanov, GR1
Kovaleva, EA1
Shevchenko, EV1
Akhmatkhanova, LK1
Wilcox, SK1
Garry, A1
Johnson, MJ1
Krivonos, OV1
Amosova, NA1
Smolentseva, IG1
Barrett, AM1
Levy, CE1
Gonzalez Rothi, LJ1
Kazui, H1
Mori, E1
Hashimoto, M1
Hirono, N1
Satou, T1
Wada, H1
Arai, H1
Sasaki, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Amantadine for Neuroenhancement in Acute Patients Study - A Prospective Pilot Proof of Concept Phase IIb Study in Intensive and Intermediate Care Unit Patients[NCT05479032]Phase 250 participants (Anticipated)Interventional2022-09-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for amantadine and Apoplexy

ArticleYear
Amantadine and Modafinil as Neurostimulants During Post-stroke Care: A Systematic Review.
    Neurocritical care, 2020, Volume: 33, Issue:1

    Topics: Amantadine; Central Nervous System Stimulants; Dopamine Agents; Humans; Modafinil; Recovery of Funct

2020

Trials

2 trials available for amantadine and Apoplexy

ArticleYear
[The use of amantadine sulfate in ischemic stroke].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2020, Volume: 120, Issue:12. Vyp. 2

    Topics: Amantadine; Brain Ischemia; Humans; Ischemic Stroke; Russia; Stroke; Treatment Outcome

2020
Use of the glutamate NMDA receptor antagonist PK-Merz in acute stroke.
    Neuroscience and behavioral physiology, 2010, Volume: 40, Issue:5

    Topics: Amantadine; Female; Humans; Male; Middle Aged; Receptors, N-Methyl-D-Aspartate; Stroke

2010

Other Studies

6 other studies available for amantadine and Apoplexy

ArticleYear
Amantadine treatment is associated with improved consciousness in patients with non-traumatic brain injury.
    Journal of neurology, neurosurgery, and psychiatry, 2022, Volume: 93, Issue:6

    Topics: Amantadine; Brain Injuries; Brain Ischemia; Consciousness; Delirium; Glasgow Coma Scale; Humans; Sei

2022
Amantadine and Modafinil as Neurostimulants Following Acute Stroke: A Retrospective Study of Intensive Care Unit Patients.
    Neurocritical care, 2021, Volume: 34, Issue:1

    Topics: Adult; Amantadine; Central Nervous System Stimulants; Humans; Intensive Care Units; Modafinil; Retro

2021
Novel use of amantadine: to treat hiccups.
    Journal of pain and symptom management, 2009, Volume: 38, Issue:3

    Topics: Aged; Amantadine; Analgesics, Non-Narcotic; Antidepressive Agents; Fatal Outcome; Hiccup; Humans; Ma

2009
Pharmaceuticals for poststroke and brain injury rehabilitation.
    American journal of physical medicine & rehabilitation, 2007, Volume: 86, Issue:8

    Topics: Amantadine; Aphasia, Broca; Brain Injuries; Dopamine Agents; Humans; Methylphenidate; Persistent Veg

2007
Phobia after bilateral thalamic hemorrhage.
    Cerebrovascular diseases (Basel, Switzerland), 2001, Volume: 12, Issue:3

    Topics: Amantadine; Cerebral Hemorrhage; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Phobic Disor

2001
[The prevention of pneumonia in the elderly by dopamine agonists].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 2001, Volume: 38, Issue:6

    Topics: Aged; Amantadine; Angiotensin-Converting Enzyme Inhibitors; Dopamine Agonists; Humans; Levodopa; Pne

2001