Page last updated: 2024-10-22

amantadine and Anxiety

amantadine has been researched along with Anxiety in 12 studies

amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source

Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.

Research Excerpts

ExcerptRelevanceReference
"Amantadine was not superior to placebo."6.72Amantadine for treatment of fatigue in Guillain-Barre syndrome: a randomised, double blind, placebo controlled, crossover trial. ( Garssen, MP; Jacobs, BC; Merkies, IS; Schmitz, PI; van der Meché, FG; van Doorn, PA, 2006)
"Nineteen patients with senile brain disease (including 2 with parkinsonian symptoms) were treated with amantadine in an oral dosage of 200--300 mg daily."5.26Amantadine in senile dementia: electroencephalographic and clinical effects. ( Boillat, J; Cole, M; Dastoor, DP; Klingner, A; Müller, HF, 1979)
"Amantadine was not superior to placebo."2.72Amantadine for treatment of fatigue in Guillain-Barre syndrome: a randomised, double blind, placebo controlled, crossover trial. ( Garssen, MP; Jacobs, BC; Merkies, IS; Schmitz, PI; van der Meché, FG; van Doorn, PA, 2006)
"Nortriptyline was reported in one study as superior for men with alcohol dependency on mean number of drinking days and on alcohol dependence, but not for severity of alcohol misuse or on the patient's or clinician's rating of drinking."2.46Pharmacological interventions for antisocial personality disorder. ( Duggan, C; Ferriter, M; Huband, N; Khalifa, N; Lieb, K; Stoffers, J; Völlm, BA, 2010)
"Amantadine treatment also reduces the production of NO and metabolism of GABA."1.56Amantadine exerts anxiolytic like effect in mice: Evidences for the involvement of nitrergic and GABAergic signaling pathways. ( Garg, C; Garg, M; Walia, V, 2020)
"Nineteen patients with senile brain disease (including 2 with parkinsonian symptoms) were treated with amantadine in an oral dosage of 200--300 mg daily."1.26Amantadine in senile dementia: electroencephalographic and clinical effects. ( Boillat, J; Cole, M; Dastoor, DP; Klingner, A; Müller, HF, 1979)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19905 (41.67)18.7374
1990's0 (0.00)18.2507
2000's4 (33.33)29.6817
2010's1 (8.33)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Walia, V1
Garg, C1
Garg, M1
Khalifa, NR1
Gibbon, S1
Völlm, BA2
Cheung, NH1
McCarthy, L1
Khalifa, N1
Duggan, C1
Stoffers, J1
Huband, N1
Ferriter, M1
Lieb, K1
Fleminger, S2
Greenwood, RJ2
Oliver, DL2
Stryjer, R1
Strous, RD1
Shaked, G1
Bar, F1
Feldman, B1
Kotler, M1
Polak, L1
Rosenzcwaig, S1
Weizman, A1
Garssen, MP1
Schmitz, PI1
Merkies, IS1
Jacobs, BC1
van der Meché, FG1
van Doorn, PA1
McFarland, HR1
Müller, HF1
Dastoor, DP1
Klingner, A1
Cole, M1
Boillat, J1
Sulcová, A1
Gulda, O1
Holmsen, R1
Barbieri, NF1
Megna, GF1
Micalizzi, V1
Pigneri, MT1
Puca, FM1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Fluoxetine on Measures of Domestic Violence[NCT00011765]Phase 2104 participants (Actual)Interventional2001-02-22Completed
Medication Development for Cocaine Dependence[NCT00249691]Phase 3180 participants (Anticipated)Interventional2005-10-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for amantadine and Anxiety

ArticleYear
Pharmacological interventions for antisocial personality disorder.
    The Cochrane database of systematic reviews, 2020, 09-03, Volume: 9

    Topics: Adult; Aggression; Alcohol-Related Disorders; Amantadine; Antisocial Personality Disorder; Anxiety;

2020
Pharmacological interventions for antisocial personality disorder.
    The Cochrane database of systematic reviews, 2020, 09-03, Volume: 9

    Topics: Adult; Aggression; Alcohol-Related Disorders; Amantadine; Antisocial Personality Disorder; Anxiety;

2020
Pharmacological interventions for antisocial personality disorder.
    The Cochrane database of systematic reviews, 2020, 09-03, Volume: 9

    Topics: Adult; Aggression; Alcohol-Related Disorders; Amantadine; Antisocial Personality Disorder; Anxiety;

2020
Pharmacological interventions for antisocial personality disorder.
    The Cochrane database of systematic reviews, 2020, 09-03, Volume: 9

    Topics: Adult; Aggression; Alcohol-Related Disorders; Amantadine; Antisocial Personality Disorder; Anxiety;

2020
Pharmacological interventions for antisocial personality disorder.
    The Cochrane database of systematic reviews, 2010, Aug-04, Issue:8

    Topics: Adult; Aggression; Alcohol-Related Disorders; Amantadine; Antisocial Personality Disorder; Anxiety;

2010
Pharmacological management for agitation and aggression in people with acquired brain injury.
    The Cochrane database of systematic reviews, 2003, Issue:1

    Topics: Adrenergic beta-Antagonists; Aggression; Amantadine; Anxiety; Brain Injuries; Humans; Methylphenidat

2003
Pharmacological management for agitation and aggression in people with acquired brain injury.
    The Cochrane database of systematic reviews, 2006, Oct-18, Issue:4

    Topics: Adrenergic beta-Antagonists; Aggression; Amantadine; Anxiety; Brain Injuries; Humans; Methylphenidat

2006

Trials

2 trials available for amantadine and Anxiety

ArticleYear
Amantadine as augmentation therapy in the management of treatment-resistant depression.
    International clinical psychopharmacology, 2003, Volume: 18, Issue:2

    Topics: Adult; Aged; Amantadine; Antidepressive Agents; Anxiety; Depressive Disorder; Dopamine Agonists; Dos

2003
Amantadine for treatment of fatigue in Guillain-Barre syndrome: a randomised, double blind, placebo controlled, crossover trial.
    Journal of neurology, neurosurgery, and psychiatry, 2006, Volume: 77, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amantadine; Antiviral Agents; Anxiety; Cross-Over Studies; Depressio

2006

Other Studies

6 other studies available for amantadine and Anxiety

ArticleYear
Amantadine exerts anxiolytic like effect in mice: Evidences for the involvement of nitrergic and GABAergic signaling pathways.
    Behavioural brain research, 2020, 02-17, Volume: 380

    Topics: Amantadine; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Brain; Diazepam; Disease Models

2020
Treating parkinsonism in the era of levodopa.
    American family physician, 1975, Volume: 12, Issue:3

    Topics: Amantadine; Antidepressive Agents; Anxiety; Depression; Histamine H1 Antagonists; Humans; Levodopa;

1975
Amantadine in senile dementia: electroencephalographic and clinical effects.
    Journal of the American Geriatrics Society, 1979, Volume: 27, Issue:1

    Topics: Administration, Oral; Aged; Amantadine; Anxiety; Dementia; Depression; Electroencephalography; Femal

1979
The behavioural effects of benzodiazepine receptor ligands in mice are inhibited by adamantylamide dipeptide.
    Activitas nervosa superior, 1989, Volume: 31, Issue:4

    Topics: Adjuvants, Immunologic; Amantadine; Animals; Anxiety; Behavior, Animal; Carbolines; Diazepam; Dipept

1989
[Amantadine treatment in parkinsonism].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1973, Oct-10, Volume: 93, Issue:28

    Topics: Administration, Oral; Amantadine; Anxiety; Hallucinations; Humans; Parkinson Disease; Sleep Wake Dis

1973
[Preliminary psychological findings during treatment of the parkinsonian syndrome with amantadine. Preliminary observations].
    Minerva medica, 1971, Oct-31, Volume: 62, Issue:82

    Topics: Amantadine; Anxiety; Depression; Dihydroxyphenylalanine; Emotions; Humans; Intelligence Tests; Menta

1971