Page last updated: 2024-10-22

amantadine and Ambulation Disorders, Neurologic

amantadine has been researched along with Ambulation Disorders, Neurologic in 12 studies

amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source

Research Excerpts

ExcerptRelevanceReference
"In advanced Parkinson's disease (PD), axial symptoms such as speech, gait, and balance impairment often become levodopa-unresponsive and they are difficult to manage, even in patients with subthalamic nucleus deep brain stimulation (STN-DBS)."2.78Amantadine improves gait in PD patients with STN stimulation. ( Chan, HF; Kukkle, PL; Lim, SY; Merello, M; Moro, E; Poon, YY, 2013)
"Levodopa is the most effective medical treatment for Parkinson disease."1.38Treatment of Parkinson disease: a 64-year-old man with motor complications of advanced Parkinson disease. ( Tarsy, D, 2012)
"Treatment included induction of coma while a native immune response matured; rabies vaccine was not administered."1.33Survival after treatment of rabies with induction of coma. ( Amlie-Lefond, CM; Chusid, MJ; Ghanayem, NS; Hoffman, GM; Rupprecht, CE; Schwabe, MJ; Tieves, KS; Willoughby, RE, 2005)
"It is mainly related to disease progression and levodopa treatment."1.31Freezing of gait in patients with advanced Parkinson's disease. ( Giladi, N; Kandinov, B; Korczyn, AD; Orlov, Y; Paleacu, D; Shabtai, H; Simon, ES; Treves, TA, 2001)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (41.67)29.6817
2010's7 (58.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Al-Shorafat, DM1
Lang, AE1
McGarry, A1
Biglan, K1
Lee, JY1
Oh, S1
Kim, JM1
Kim, JS2
Oh, E1
Kim, HT1
Jeon, BS2
Cho, JW1
Zhang, LL1
Canning, SD1
Wang, XP1
Kim, YE1
Yun, JY1
Tarsy, D1
Chan, HF1
Kukkle, PL1
Merello, M1
Lim, SY1
Poon, YY1
Moro, E1
Takahashi, H1
Shinohara, Y1
Willoughby, RE1
Tieves, KS1
Hoffman, GM1
Ghanayem, NS1
Amlie-Lefond, CM1
Schwabe, MJ1
Chusid, MJ1
Rupprecht, CE1
Giladi, N1
Treves, TA1
Simon, ES1
Shabtai, H1
Orlov, Y1
Kandinov, B1
Paleacu, D1
Korczyn, AD1
Baezner, H1
Oster, M1
Henning, O1
Cohen, S1
Hennerici, MG1
Lee, KJ1
Guak, TH1
Kim, BS1
Yang, DW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Experimentally-induced Freezing of Gait in Parkinson's Disease by Modulating Step Length/Asymmetry and Cognitive/Visual Loading[NCT04799613]20 participants (Anticipated)Interventional2021-03-15Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for amantadine and Ambulation Disorders, Neurologic

ArticleYear
Freezing of Gait in Parkinsonism and its Potential Drug Treatment.
    Current neuropharmacology, 2016, Volume: 14, Issue:4

    Topics: Aged; Aged, 80 and over; Amantadine; Antiparkinson Agents; Botulinum Toxins; Droxidopa; Gait Disorde

2016
[Diagnosis and therapy for patients with vascular parkinsonism].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2003, Aug-10, Volume: 92, Issue:8

    Topics: Akinetic Mutism; Amantadine; Antiparkinson Agents; Cerebral Infarction; Dementia, Vascular; Diagnosi

2003

Trials

4 trials available for amantadine and Ambulation Disorders, Neurologic

ArticleYear
Intravenous amantadine on freezing of gait in Parkinson's disease: a randomized controlled trial.
    Journal of neurology, 2013, Volume: 260, Issue:12

    Topics: Aged; Amantadine; Antiparkinson Agents; Double-Blind Method; Gait; Gait Disorders, Neurologic; Human

2013
Effect of intravenous amantadine on dopaminergic-drug-resistant freezing of gait.
    Parkinsonism & related disorders, 2011, Volume: 17, Issue:6

    Topics: Aged; Amantadine; Antiparkinson Agents; Gait Disorders, Neurologic; Humans; Infusions, Intravenous;

2011
Amantadine improves gait in PD patients with STN stimulation.
    Parkinsonism & related disorders, 2013, Volume: 19, Issue:3

    Topics: Adult; Amantadine; Antiparkinson Agents; Combined Modality Therapy; Deep Brain Stimulation; Female;

2013
Amantadine increases gait steadiness in frontal gait disorder due to subcortical vascular encephalopathy: a double-blind randomized placebo-controlled trial based on quantitative gait analysis.
    Cerebrovascular diseases (Basel, Switzerland), 2001, Volume: 11, Issue:3

    Topics: Amantadine; Antiparkinson Agents; Brain; Dementia, Vascular; Double-Blind Method; Gait; Gait Disorde

2001

Other Studies

6 other studies available for amantadine and Ambulation Disorders, Neurologic

ArticleYear
Amantadine for Gait Dysfunction in Pantothenate Kinase-Associated Neurodegeneration.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2019, Volume: 46, Issue:6

    Topics: Adolescent; Amantadine; Dopamine Agents; Female; Gait; Gait Disorders, Neurologic; Humans; Male; Pan

2019
Improvement of freezing of gait with amantadine in a patient with oculopharyngeal muscular dystrophy and Parkinsonism.
    Parkinsonism & related disorders, 2013, Volume: 19, Issue:6

    Topics: Aged; Amantadine; Antiparkinson Agents; Freezing Reaction, Cataleptic; Gait Disorders, Neurologic; H

2013
Treatment of Parkinson disease: a 64-year-old man with motor complications of advanced Parkinson disease.
    JAMA, 2012, Jun-06, Volume: 307, Issue:21

    Topics: Amantadine; Antiparasitic Agents; Carbidopa; Catechols; Decision Making; Deep Brain Stimulation; Dis

2012
Survival after treatment of rabies with induction of coma.
    The New England journal of medicine, 2005, Jun-16, Volume: 352, Issue:24

    Topics: Adolescent; Amantadine; Anesthetics; Animals; Antiviral Agents; Athetosis; Benzodiazepines; Bites an

2005
Freezing of gait in patients with advanced Parkinson's disease.
    Journal of neural transmission (Vienna, Austria : 1996), 2001, Volume: 108, Issue:1

    Topics: Adult; Age of Onset; Amantadine; Antiparkinson Agents; Disease Progression; Dopamine Agonists; Femal

2001
Gait ignition failure after unilateral anteromedial pallidotomy.
    European neurology, 2001, Volume: 46, Issue:1

    Topics: Amantadine; Dopamine Agents; Female; Functional Laterality; Gait Disorders, Neurologic; Globus Palli

2001