amantadine has been researched along with Alzheimer Disease in 18 studies
amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (27.78) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 4 (22.22) | 29.6817 |
| 2010's | 5 (27.78) | 24.3611 |
| 2020's | 2 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Turcu, AL | 1 |
| Companys-Alemany, J | 1 |
| Phillips, MB | 1 |
| Patel, DS | 1 |
| Griñán-Ferré, C | 1 |
| Loza, MI | 1 |
| Brea, JM | 1 |
| Pérez, B | 1 |
| Soto, D | 1 |
| Sureda, FX | 1 |
| Kurnikova, MG | 1 |
| Johnson, JW | 1 |
| Pallàs, M | 1 |
| Vázquez, S | 1 |
| Müller, T | 1 |
| Riederer, P | 1 |
| Kuhn, W | 1 |
| Bachurin, SO | 1 |
| Shevtsova, EF | 1 |
| Makhaeva, GF | 1 |
| Grigoriev, VV | 1 |
| Boltneva, NP | 1 |
| Kovaleva, NV | 1 |
| Lushchekina, SV | 1 |
| Shevtsov, PN | 1 |
| Neganova, ME | 1 |
| Redkozubova, OM | 1 |
| Bovina, EV | 1 |
| Gabrelyan, AV | 1 |
| Fisenko, VP | 1 |
| Sokolov, VB | 1 |
| Aksinenko, AY | 1 |
| Echeverria, V | 1 |
| Barreto, GE | 1 |
| Aliev, G | 1 |
| Spilovska, K | 2 |
| Korabecny, J | 2 |
| Kral, J | 1 |
| Horova, A | 1 |
| Musilek, K | 1 |
| Soukup, O | 2 |
| Drtinova, L | 2 |
| Gazova, Z | 2 |
| Siposova, K | 2 |
| Kuca, K | 2 |
| Meng, F | 1 |
| Dai, E | 1 |
| Yu, X | 1 |
| Zhang, Y | 1 |
| Chen, X | 1 |
| Liu, X | 1 |
| Wang, S | 1 |
| Wang, L | 1 |
| Jiang, W | 1 |
| Sepsova, V | 1 |
| Jost, P | 1 |
| Nepovimova, E | 1 |
| Fedunova, D | 1 |
| Horak, M | 1 |
| Kaniakova, M | 1 |
| Wang, ZJ | 1 |
| Hamouda, AK | 1 |
| Yeh, HH | 1 |
| Yang, YH | 1 |
| Chen, SH | 1 |
| Grützner, L | 1 |
| Baezner, H | 1 |
| Daffertshofer, M | 1 |
| Dell'Antone, P | 1 |
| IbnLkayat, M | 1 |
| Drago, D | 1 |
| Zatta, P | 1 |
| Lerner, AJ | 1 |
| Strauss, M | 1 |
| Sami, SA | 1 |
| Kornhuber, J | 1 |
| Weller, M | 1 |
| Schinitsky, MR | 1 |
| Erkulwater, S | 1 |
| Pillai, R | 1 |
| Otomo, E | 1 |
| Davidson, M | 1 |
| Powchik, P | 1 |
| Davis, KL | 1 |
| Fleischhacker, WW | 1 |
| Buchgeher, A | 1 |
| Schubert, H | 1 |
| Rosse, R | 1 |
| Ciolino, C | 1 |
3 reviews available for amantadine and Alzheimer Disease
| Article | Year |
|---|---|
[Subcortical vascular encephalopathy].
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amantadine; Brain; Carbamates; Clinical Trials as Topic; | 2003 |
Recognizing apathy in Alzheimer's disease.
Topics: Affective Symptoms; Aged; Alzheimer Disease; Amantadine; Cognition Disorders; Depressive Disorder, M | 2007 |
[New therapeutic possibilities with low-affinity NMDA receptor antagonists].
Topics: Aged; Alzheimer Disease; Amantadine; Antiparkinson Agents; Excitatory Amino Acid Antagonists; Glutam | 1996 |
1 trial available for amantadine and Alzheimer Disease
| Article | Year |
|---|---|
Memantine in the treatment of senile dementia of the Alzheimer type.
Topics: Aged; Alzheimer Disease; Amantadine; Clinical Trials as Topic; Female; Humans; Male; Memantine; Rand | 1986 |
14 other studies available for amantadine and Alzheimer Disease
| Article | Year |
|---|---|
Design, synthesis, and in vitro and in vivo characterization of new memantine analogs for Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Caenorhabditis elegans; Disease Models, Animal; Memantine; Mice; Recepto | 2022 |
Aminoadamantanes: from treatment of Parkinson's and Alzheimer's disease to symptom amelioration of long COVID-19 syndrome?
Topics: Alzheimer Disease; Amantadine; COVID-19; Humans; Memantine; Parkinson Disease; Post-Acute COVID-19 S | 2023 |
Novel conjugates of aminoadamantanes with carbazole derivatives as potential multitarget agents for AD treatment.
Topics: Alzheimer Disease; Amantadine; Carbazoles; Carboxylesterase; Cholinesterase Inhibitors; Drug Design; | 2017 |
7-Methoxytacrine-adamantylamine heterodimers as cholinesterase inhibitors in Alzheimer's disease treatment--synthesis, biological evaluation and molecular modeling studies.
Topics: Acetylcholinesterase; Alzheimer Disease; Amantadine; Cholinesterase Inhibitors; Dimerization; Enzyme | 2013 |
Constructing and characterizing a bioactive small molecule and microRNA association network for Alzheimer's disease.
Topics: Alzheimer Disease; Amantadine; Computational Biology; Gene Expression Regulation; Heterocyclic Compo | 2014 |
Multi-target-directed therapeutic potential of 7-methoxytacrine-adamantylamine heterodimers in the Alzheimer's disease treatment.
Topics: Alzheimer Disease; Amantadine; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; | 2017 |
Simultaneous determination of memantine and amantadine in human plasma as fluorescein derivatives by micellar electrokinetic chromatography with laser-induced fluorescence detection and its clinical application.
Topics: Acetonitriles; Alzheimer Disease; Amantadine; Antiparkinson Agents; Chemical Fractionation; Chromato | 2010 |
[Case report. Dementia with apathy].
Topics: Administration, Oral; Aged; Alzheimer Disease; Amantadine; Bronchopneumonia; Confusion; Dehydration; | 2002 |
Acidic vesicles of the endo-exocytic pathways as targets for some anti-monoamine oxidase drugs.
Topics: Acid-Base Equilibrium; Acids; Alzheimer Disease; Amantadine; Animals; Brain; Brain Chemistry; Brain | 2009 |
A potential treatment for Alzheimer's disease?
Topics: Alzheimer Disease; Amantadine; Humans | 1991 |
Amantadine and the end-stage dementia of Alzheimer's type.
Topics: Aged; Alzheimer Disease; Amantadine; Electroencephalography; Humans; Male; Palliative Care | 1989 |
[Drug therapy of Alzheimer's disease. General concepts on nootropic drugs].
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amantadine; Aminoacridines; Dementia; gamma-Aminobutyric | 1988 |
Pisa syndrome in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Amantadine; Drug Therapy, Combination; Dystonia; Haloperidol; Humans; Male; | 1988 |
Dopamine agonists and neuroleptic malignant syndrome.
Topics: Alzheimer Disease; Amantadine; Basal Ganglia Diseases; Bromocriptine; Dantrolene; Humans; Male; Midd | 1985 |