Page last updated: 2024-10-22

amantadine and Aging

amantadine has been researched along with Aging in 11 studies

amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
" Drugs used to treat PD, such as levodopa, offer symptomatic relief but often have neuropsychiatric adverse effects, most prominently psychosis and delirium."4.79Neuropsychiatric adverse effects of antiparkinsonian drugs. Characteristics, evaluation and treatment. ( Camicioli, R; Ganzini, L; Young, BK, 1997)
"Epidemic influenza occurred only in the two groups of conscripts: the incidence of serologically verified influenza was 66% and 83% in the groups that received placebo and 43% and 51% in the groups that received amantadine, giving protection rates of 36% (P = 0."2.65Evaluation of amantadine in the prophylaxis of influenza A (H1N1) virus infection: a controlled field trial among young adults and high-risk patients. ( Hellström, PE; Penttinen, K; Pettersson, RF; Pyhälä, R; Tokola, O; Vartio, T; Visakorpi, R, 1980)
"The development of pneumonia is a life-threatening event in a nursing home resident."2.37Pneumonia in the elderly: a nursing home perspective. ( Gleckman, RA; Roth, RM, 1985)
"Amantadine was administered to 676 patients with influenza A (A+Am group)."1.33Factors influencing the effectiveness of oseltamivir and amantadine for the treatment of influenza: a multicenter study from Japan of the 2002-2003 influenza season. ( Hirotsu, N; Ikematsu, H; Iwaki, N; Kashiwagi, S; Kawai, N; Kawashima, T; Maeda, T; Miyachi, K; Satoh, I; Shigematsu, T, 2005)
"Vaccination is more difficult for influenza than for pneumococcal pneumonia."1.27Vaccinating the elderly: recommendations and rationale. ( Alvarez, S; Berk, SL, 1986)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19906 (54.55)18.7374
1990's2 (18.18)18.2507
2000's3 (27.27)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kasná, A1
Turánek, J1
Vacek, A1
Záluská, D1
Knötigová, P1
Masek, K1
Kawai, N1
Ikematsu, H1
Iwaki, N1
Satoh, I1
Kawashima, T1
Maeda, T1
Miyachi, K1
Hirotsu, N1
Shigematsu, T1
Kashiwagi, S1
Pettersson, RF1
Hellström, PE1
Penttinen, K1
Pyhälä, R1
Tokola, O1
Vartio, T1
Visakorpi, R1
Gaudry, SE1
Sitar, DS1
Smyth, DD1
McKenzie, JK1
Aoki, FY1
Young, BK1
Camicioli, R1
Ganzini, L1
Vamvakidès, A1
Greer, M1
Mostow, SR1
Roth, RM1
Gleckman, RA1
Berk, SL1
Alvarez, S1
Bunn, PA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Urinary Excretion of Acetylamantadine by Cancer Patients[NCT02277938]120 participants (Anticipated)Observational2013-08-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for amantadine and Aging

ArticleYear
Neuropsychiatric adverse effects of antiparkinsonian drugs. Characteristics, evaluation and treatment.
    Drugs & aging, 1997, Volume: 10, Issue:5

    Topics: Aging; Akathisia, Drug-Induced; Amantadine; Antiparkinson Agents; Antipsychotic Agents; Cholinergic

1997
Pneumonia in the elderly: a nursing home perspective.
    American family physician, 1985, Volume: 31, Issue:2

    Topics: Aged; Aging; Amantadine; Anti-Bacterial Agents; Bacterial Vaccines; Diagnosis, Differential; Humans;

1985

Trials

2 trials available for amantadine and Aging

ArticleYear
Evaluation of amantadine in the prophylaxis of influenza A (H1N1) virus infection: a controlled field trial among young adults and high-risk patients.
    The Journal of infectious diseases, 1980, Volume: 142, Issue:3

    Topics: Adult; Aged; Aging; Amantadine; Antibodies, Viral; Clinical Trials as Topic; Disease Outbreaks; Doub

1980
Gender and age as factors in the inhibition of renal clearance of amantadine by quinine and quinidine.
    Clinical pharmacology and therapeutics, 1993, Volume: 54, Issue:1

    Topics: Adult; Aged; Aging; Amantadine; Analysis of Variance; Drug Interactions; Female; Humans; Kidney; Mal

1993

Other Studies

7 other studies available for amantadine and Aging

ArticleYear
Restoration of femoral GM-CFC progenitors in sublethally irradiated mice of various ages treated with liposomal adamantylamide dipeptide.
    International immunopharmacology, 2004, Volume: 4, Issue:8

    Topics: Aging; Amantadine; Animals; Cells, Cultured; Dipeptides; Dose-Response Relationship, Radiation; Fema

2004
Factors influencing the effectiveness of oseltamivir and amantadine for the treatment of influenza: a multicenter study from Japan of the 2002-2003 influenza season.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, May-01, Volume: 40, Issue:9

    Topics: Acetamides; Adolescent; Adult; Aged; Aging; Amantadine; Antiviral Agents; Child; Child, Preschool; F

2005
[Effect of amantadine or 3-cyclopentyl adamantanamine on the immobility of adult or aged mice, in the forced swim test].
    Annales pharmaceutiques francaises, 2000, Volume: 58, Issue:6

    Topics: Adamantane; Aging; Amantadine; Animals; Antiparkinson Agents; Brain; Imipramine; Male; Mice; Mice, I

2000
Recent developments in the treatment of Parkinson's disease.
    Geriatrics, 1985, Volume: 40, Issue:2

    Topics: Aged; Aging; Amantadine; Diagnosis, Differential; Drug Administration Schedule; Dyskinesia, Drug-Ind

1985
Steven R. Mostow, MD: why vaccinate the elderly?. Interview by Richard L. Peck.
    Geriatrics, 1987, Volume: 42, Issue:11

    Topics: Aged; Aging; Amantadine; Humans; Influenza Vaccines; Influenza, Human

1987
Vaccinating the elderly: recommendations and rationale.
    Geriatrics, 1986, Volume: 41, Issue:1

    Topics: Aged; Aging; Amantadine; Creatinine; Female; Humans; Influenza Vaccines; Influenza, Human; Male; Mid

1986
Pneumonia in the older patient.
    Journal of the American Geriatrics Society, 1968, Volume: 16, Issue:1

    Topics: Aged; Aging; Amantadine; Anti-Bacterial Agents; Cephalosporins; DNA Nucleotidyltransferases; Gentami

1968