amantadine has been researched along with Aggression in 20 studies
amant: an antiviral compound consisting of an adamantane derivative chemically linked to a water-solube polyanioic matrix; structure in first source
Aggression: Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amantadine was well tolerated." | 6.70 | Case series: amantadine open-label treatment of impulsive and aggressive behavior in hospitalized children with developmental disabilities. ( Dourish, CT; King, BH; Snape, M; Wright, DM, 2001) |
| " Following repeated administration of the higher dose of IMI together with AMA, we observed an increase in clonidine-induced aggression in mice, and significant enhancement of D-amphetamine-induced locomotor hyperactivity, as well as phenylephrine-induced exploratory behavior, in rats." | 3.72 | The effect of combined treatment with imipramine and amantadine on the behavioral reactivity of central alpha1-adrenergic system in rats. ( Dziedzicka-Wasylewska, M; Faron-Górecka, A; Rogóz, Z; Solich, J, 2004) |
| " The drug does not possess an antidepressant action proper but activates the aggressive-defensive behaviour in experimental reserpine depression and reduces the provocation-induced aggressive behaviour in experimental haloperidol depression." | 3.66 | [Psychopharmacologic spectrum of melanostatin]. ( Klusha, VE; Kozlovskaia, MM; Svirskis, ShV; Val'dman, AV, 1980) |
| " A retrospective review of electronic medical records was conducted by researchers and data were collected on the following measures: ordered psycho-pharmacological agents, frequency, dosing and duration of orders, whether each administered psycho-pharmacological agent was started before or after psychiatric consultation, and psycho-pharmacological agents prescribed upon discharge." | 2.82 | A descriptive analysis of pharmacological management of aggression and/or agitation in patients with traumatic brain injury in a Southwest Virginia inpatient population. ( Kablinger, A; Lemelle, T; Rahmani, E; Sharp, H; Smarbafzadeh, E, 2022) |
| "Amantadine was well tolerated." | 2.70 | Case series: amantadine open-label treatment of impulsive and aggressive behavior in hospitalized children with developmental disabilities. ( Dourish, CT; King, BH; Snape, M; Wright, DM, 2001) |
| "Nortriptyline was reported in one study as superior for men with alcohol dependency on mean number of drinking days and on alcohol dependence, but not for severity of alcohol misuse or on the patient's or clinician's rating of drinking." | 2.46 | Pharmacological interventions for antisocial personality disorder. ( Duggan, C; Ferriter, M; Huband, N; Khalifa, N; Lieb, K; Stoffers, J; Völlm, BA, 2010) |
| "Amantadine has a growing body of evidence for the treatment of aggressive behavior in patients with traumatic brain injury, autism spectrum disorder, and developmental disability." | 1.43 | Adjunctive Amantadine Treatment for Aggressive Behavior in Children: A Series of Eight Cases. ( Loveland, JG; McGrane, IR; Zaluski, HJ, 2016) |
| "Two patients with advanced Huntington's disease manifested a marked increase in irritability and aggressiveness when treated with amantadine during an epidemic of influenza." | 1.27 | Adverse behavioral effects of amantadine therapy in Huntington's disease. ( Stewart, JT, 1987) |
| "3) Amantadine was equipotent to imipramine in suppressing haloperidol-induced catalepsy in rats, but L-DOPA was without effect." | 1.27 | [Behavioral pharmacology of amantadine with special references to the effect on abnormal behavior in mice and rats]. ( Fujiwara, M; Kiyota, Y; Ohta, H; Sakurai, Y; Shibata, S; Shimazoe, T; Ueki, S, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (45.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (25.00) | 29.6817 |
| 2010's | 4 (20.00) | 24.3611 |
| 2020's | 2 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rahmani, E | 1 |
| Lemelle, T | 1 |
| Sharp, H | 1 |
| Smarbafzadeh, E | 1 |
| Kablinger, A | 1 |
| Khalifa, NR | 1 |
| Gibbon, S | 1 |
| Völlm, BA | 2 |
| Cheung, NH | 1 |
| McCarthy, L | 1 |
| Gwynette, MF | 1 |
| Beck, B | 1 |
| VandenBerg, A | 1 |
| Stocking, N | 1 |
| Luauté, J | 1 |
| Plantier, D | 1 |
| Wiart, L | 1 |
| Tell, L | 1 |
| McGrane, IR | 1 |
| Loveland, JG | 1 |
| Zaluski, HJ | 1 |
| Khalifa, N | 1 |
| Duggan, C | 1 |
| Stoffers, J | 1 |
| Huband, N | 1 |
| Ferriter, M | 1 |
| Lieb, K | 1 |
| Fleminger, S | 2 |
| Greenwood, RJ | 2 |
| Oliver, DL | 2 |
| Dziedzicka-Wasylewska, M | 1 |
| Faron-Górecka, A | 1 |
| Rogóz, Z | 1 |
| Solich, J | 1 |
| Sugden, SG | 1 |
| Kile, SJ | 1 |
| Farrimond, DD | 1 |
| Hilty, DM | 1 |
| Bourgeois, JA | 1 |
| Val'dman, AV | 1 |
| Kozlovskaia, MM | 1 |
| Klusha, VE | 1 |
| Svirskis, ShV | 1 |
| King, BH | 1 |
| Wright, DM | 1 |
| Snape, M | 1 |
| Dourish, CT | 1 |
| Pradhan, SN | 1 |
| Anand, M | 1 |
| Gupta, GP | 1 |
| Bhargava, KP | 1 |
| Senault, B | 1 |
| Sulcová, A | 2 |
| Gulda, O | 2 |
| Krsiak, M | 1 |
| Masek, K | 1 |
| Stewart, JT | 1 |
| Fujiwara, M | 1 |
| Sakurai, Y | 1 |
| Kiyota, Y | 1 |
| Shimazoe, T | 1 |
| Ohta, H | 1 |
| Shibata, S | 1 |
| Ueki, S | 1 |
| Rizzo, M | 1 |
| Morselli, PL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Fluoxetine on Measures of Domestic Violence[NCT00011765] | Phase 2 | 104 participants (Actual) | Interventional | 2001-02-22 | Completed | ||
| Medication Development for Cocaine Dependence[NCT00249691] | Phase 3 | 180 participants (Anticipated) | Interventional | 2005-10-31 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for amantadine and Aggression
| Article | Year |
|---|---|
A descriptive analysis of pharmacological management of aggression and/or agitation in patients with traumatic brain injury in a Southwest Virginia inpatient population.
Topics: Adrenergic beta-Antagonists; Adult; Aggression; Amantadine; Anticonvulsants; Antipsychotic Agents; B | 2022 |
Pharmacological interventions for antisocial personality disorder.
Topics: Adult; Aggression; Alcohol-Related Disorders; Amantadine; Antisocial Personality Disorder; Anxiety; | 2020 |
Pharmacological interventions for antisocial personality disorder.
Topics: Adult; Aggression; Alcohol-Related Disorders; Amantadine; Antisocial Personality Disorder; Anxiety; | 2020 |
Pharmacological interventions for antisocial personality disorder.
Topics: Adult; Aggression; Alcohol-Related Disorders; Amantadine; Antisocial Personality Disorder; Anxiety; | 2020 |
Pharmacological interventions for antisocial personality disorder.
Topics: Adult; Aggression; Alcohol-Related Disorders; Amantadine; Antisocial Personality Disorder; Anxiety; | 2020 |
Care management of the agitation or aggressiveness crisis in patients with TBI. Systematic review of the literature and practice recommendations.
Topics: Adrenergic beta-Antagonists; Aggression; Amantadine; Anti-Anxiety Agents; Anticonvulsants; Antipsych | 2016 |
Pharmacological interventions for antisocial personality disorder.
Topics: Adult; Aggression; Alcohol-Related Disorders; Amantadine; Antisocial Personality Disorder; Anxiety; | 2010 |
Pharmacological management for agitation and aggression in people with acquired brain injury.
Topics: Adrenergic beta-Antagonists; Aggression; Amantadine; Anxiety; Brain Injuries; Humans; Methylphenidat | 2003 |
Pharmacological management for agitation and aggression in people with acquired brain injury.
Topics: Adrenergic beta-Antagonists; Aggression; Amantadine; Anxiety; Brain Injuries; Humans; Methylphenidat | 2006 |
Aggression and central neurotransmitters.
Topics: Acetylcholinesterase; Aggression; Amantadine; Animals; Apomorphine; Brain; Carbachol; Choline O-Acet | 1975 |
1 trial available for amantadine and Aggression
| Article | Year |
|---|---|
Case series: amantadine open-label treatment of impulsive and aggressive behavior in hospitalized children with developmental disabilities.
Topics: Aggression; Amantadine; Brain Diseases; Child; Child, Preschool; Developmental Disabilities; Disrupt | 2001 |
12 other studies available for amantadine and Aggression
| Article | Year |
|---|---|
Under arrest: the use of amantadine for treatment-refractory mood lability and aggression in a patient with traumatic brain injury.
Topics: Aggression; Amantadine; Brain Injuries; Criminals; Dopamine Agents; Humans; Male; Middle Aged; Mood | 2015 |
Adjunctive Amantadine Treatment for Aggressive Behavior in Children: A Series of Eight Cases.
Topics: Aggression; Amantadine; Child; Dopamine Agents; Dose-Response Relationship, Drug; Female; Humans; In | 2016 |
The effect of combined treatment with imipramine and amantadine on the behavioral reactivity of central alpha1-adrenergic system in rats.
Topics: Administration, Oral; Adrenergic alpha-1 Receptor Agonists; Aggression; Amantadine; Amphetamine; Ani | 2004 |
Pharmacological intervention for cognitive deficits and aggression in frontal lobe injury.
Topics: Adult; Aggression; Amantadine; Cognition Disorders; Conduct Disorder; Donepezil; Frontal Lobe; Human | 2006 |
[Psychopharmacologic spectrum of melanostatin].
Topics: Aggression; Amantadine; Animals; Behavior, Animal; Biogenic Amines; Brain Chemistry; Catalepsy; Cats | 1980 |
Modification of electroshock fighting by drugs known to interact with dopaminergic and noradrenergic neurons in normal and brain lesioned rats.
Topics: Aggression; Amantadine; Animals; Apomorphine; Brain; Ditiocarb; Dopamine; Electroshock; Humans; Imip | 1977 |
[Amantadine: aggressive effect; effect on apomorphine-induced aggressivity in the rat].
Topics: Aggression; Amantadine; Animals; Apomorphine; Dose-Response Relationship, Drug; Humans; Rats | 1976 |
The immunomodulators levamisole, muramyl dipeptide and adamantylamide dipeptide antagonize the antianxiety effect of diazepam.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Aggression; Agonistic Behavior; Amantadine; Animals; Anti-Anxiety | 1989 |
Behavioural effects of muramyl dipeptide and adamantylamide dipeptide in mice.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adjuvants, Immunologic; Aggression; Agonistic Behavior; Amantadin | 1989 |
Adverse behavioral effects of amantadine therapy in Huntington's disease.
Topics: Adult; Aggression; Amantadine; Humans; Huntington Disease; Influenza, Human; Male | 1987 |
[Behavioral pharmacology of amantadine with special references to the effect on abnormal behavior in mice and rats].
Topics: Aggression; Amantadine; Animals; Behavior, Animal; Catalepsy; Central Nervous System; Dronabinol; Ha | 1985 |
Amantadine-induced aggressiveness.
Topics: Aged; Aggression; Amantadine; Depression; Humans; Motor Activity | 1972 |