am 580 and Pregnancy
am 580 has been researched along with Pregnancy in 5 studies
Am 580: a selctive retinoic acid receptor (alpha) agonist; structure given in first source
4-{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino}benzoic acid : An amidobenzoic acid obtained by formal condensation of the carboxy group of (5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)benzoic acid with the anilino group of 4-aminobenzoic acid. A selective RARalpha agonist.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
Research
Studies (5)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Elmazar, MM | 4 |
| Nau, H | 4 |
| Eckhardt, K | 1 |
| Schmitt, G | 1 |
| Reichert, U | 2 |
| Shroot, B | 2 |
| Arafa, HM | 2 |
| Hamada, FM | 2 |
Other Studies
5 other studies available for am 580 and Pregnancy
| Article | Year |
|---|---|
Potentiation of the teratogenic effects induced by coadministration of retinoic acid or phytanic acid/phytol with synthetic retinoid receptor ligands.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Benzoates; Bexarotene; Dose-Response Rel | 2004 |
A retinoic acid receptor alpha antagonist counteracts retinoid teratogenicity in vitro and reduced incidence and/or severity of malformations in vivo.
Topics: Abnormalities, Drug-Induced; Animals; Benzoates; Cell Differentiation; Cells, Cultured; Chromans; Cl | 1994 |
Pattern of retinoid-induced teratogenic effects: possible relationship with relative selectivity for nuclear retinoid receptors RAR alpha, RAR beta, and RAR gamma.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Administration, Oral; Animals; Benzoates; Bone | 1996 |
Fully automated determination of selective retinoic acid receptor ligands in mouse plasma and tissue by reversed-phase liquid chromatography coupled on-line with solid-phase extraction.
Topics: Animals; Antineoplastic Agents; Autoanalysis; Benzoates; Calibration; Chromatography, High Pressure | 1996 |
Selective agonists of retinoic acid receptors: comparative toxicokinetics and embryonic exposure.
Topics: Abnormalities, Drug-Induced; Animals; Area Under Curve; Benzoates; Embryo, Mammalian; Female; Matern | 2000 |