am 580 has been researched along with Alloxan Diabetes in 1 studies
Am 580: a selctive retinoic acid receptor (alpha) agonist; structure given in first source
4-{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino}benzoic acid : An amidobenzoic acid obtained by formal condensation of the carboxy group of (5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)benzoic acid with the anilino group of 4-aminobenzoic acid. A selective RARalpha agonist.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether retinoic acid (RA)-mediated inhibition of deregulated calpains had any effect on the development of cataract given that accumulating evidence has demonstrated a possible relationship between cataractogenesis and inappropriate activation of calpains." | 7.74 | Inhibitory effects of retinoic acid receptor alpha stimulants on murine cataractogenesis through suppression of deregulated calpains. ( Chiba, H; Kojima, T; Nishikiori, N; Ohguro, H; Osanai, M; Sawada, N, 2007) |
| "To determine whether retinoic acid (RA)-mediated inhibition of deregulated calpains had any effect on the development of cataract given that accumulating evidence has demonstrated a possible relationship between cataractogenesis and inappropriate activation of calpains." | 3.74 | Inhibitory effects of retinoic acid receptor alpha stimulants on murine cataractogenesis through suppression of deregulated calpains. ( Chiba, H; Kojima, T; Nishikiori, N; Ohguro, H; Osanai, M; Sawada, N, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nishikiori, N | 1 |
| Osanai, M | 1 |
| Chiba, H | 1 |
| Kojima, T | 1 |
| Ohguro, H | 1 |
| Sawada, N | 1 |
1 other study available for am 580 and Alloxan Diabetes
| Article | Year |
|---|---|
Inhibitory effects of retinoic acid receptor alpha stimulants on murine cataractogenesis through suppression of deregulated calpains.
Topics: Animals; Benzoates; Calcium; Calpain; Cataract; Diabetes Mellitus, Experimental; Hydrogen Peroxide; | 2007 |