am-356 and Inflammation

am-356 has been researched along with Inflammation* in 1 studies

Other Studies

1 other study(ies) available for am-356 and Inflammation

Article	Year
( R)- N-(1-Methyl-2-hydroxyethyl)-13-( S)-methyl-arachidonamide (AMG315): A Novel Chiral Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes. Journal of medicinal chemistry, 2018, 10-11, Volume: 61, Issue:19 The synthesis of potent metabolically stable endocannabinoids is challenging. Here we report a chiral arachidonoyl ethanolamide (AEA) analogue, namely, (13 S,1' R)-dimethylanandamide (AMG315, 3a), a high affinity ligand for the CB1 receptor ( K Topics: Amidohydrolases; Analgesics; Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Enzyme Stability; Freund's Adjuvant; HEK293 Cells; Humans; Hyperalgesia; Inflammation; Lectins, C-Type; Male; Mice; Mice, Knockout; Monoacylglycerol Lipases; Nociception; Rats; Receptor, Cannabinoid, CB1	2018

Article

Year

( R)- N-(1-Methyl-2-hydroxyethyl)-13-( S)-methyl-arachidonamide (AMG315): A Novel Chiral Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes.

Journal of medicinal chemistry, 2018, 10-11, Volume: 61, Issue:19

The synthesis of potent metabolically stable endocannabinoids is challenging. Here we report a chiral arachidonoyl ethanolamide (AEA) analogue, namely, (13 S,1' R)-dimethylanandamide (AMG315, 3a), a high affinity ligand for the CB1 receptor ( K

Topics: Amidohydrolases; Analgesics; Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Enzyme Stability; Freund's Adjuvant; HEK293 Cells; Humans; Hyperalgesia; Inflammation; Lectins, C-Type; Male; Mice; Mice, Knockout; Monoacylglycerol Lipases; Nociception; Rats; Receptor, Cannabinoid, CB1

2018