am 251 has been researched along with Vomiting in 5 studies
AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.
Vomiting: The forcible expulsion of the contents of the STOMACH through the MOUTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The results suggest that prolonging the action of anandamide by pretreatment with the FAAH inhibitor, URB597, suppresses lithium-induced nausea in the rat." | 7.74 | Effects of the FAAH inhibitor, URB597, and anandamide on lithium-induced taste reactivity responses: a measure of nausea in the rat. ( Cross-Mellor, SK; Ossenkopp, KP; Parker, LA; Piomelli, D, 2007) |
| "Emesis was induced in ferrets with morphine-6-glucuronide (0." | 7.74 | A unique therapeutic approach to emesis and itch with a proanthocyanidin-rich genonutrient. ( Miller, MJ; Reuter, BK; Sharkey, KA; Wallace, JL, 2008) |
| "The results suggest that prolonging the action of anandamide by pretreatment with the FAAH inhibitor, URB597, suppresses lithium-induced nausea in the rat." | 3.74 | Effects of the FAAH inhibitor, URB597, and anandamide on lithium-induced taste reactivity responses: a measure of nausea in the rat. ( Cross-Mellor, SK; Ossenkopp, KP; Parker, LA; Piomelli, D, 2007) |
| "Emesis was induced in ferrets with morphine-6-glucuronide (0." | 3.74 | A unique therapeutic approach to emesis and itch with a proanthocyanidin-rich genonutrient. ( Miller, MJ; Reuter, BK; Sharkey, KA; Wallace, JL, 2008) |
| "Retching and vomiting responses increased with increasing morphine doses up to 1." | 3.71 | The cannabinoid agonist WIN55,212-2 suppresses opioid-induced emesis in ferrets. ( Hamza, MS; Makriyannis, A; Malan, TP; Mata, HP; Porreca, F; Siegel, EM; Simoneau, II; Vanderah, TW, 2001) |
| "Vomiting was assessed in shrews (Suncus murinus), pretreated with JZL184, a selective monoacylglycerol lipase (MAGL) inhibitor which elevates endogenous 2AG levels, 1 h before administering the emetogenic compound, LiCl." | 1.38 | Inhibition of monoacylglycerol lipase attenuates vomiting in Suncus murinus and 2-arachidonoyl glycerol attenuates nausea in rats. ( Cravatt, BF; Limebeer, CL; Long, JZ; Mechoulam, R; Parker, LA; Rock, EM; Sticht, MA, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sticht, MA | 1 |
| Long, JZ | 1 |
| Rock, EM | 1 |
| Limebeer, CL | 1 |
| Mechoulam, R | 1 |
| Cravatt, BF | 1 |
| Parker, LA | 2 |
| Cross-Mellor, SK | 1 |
| Ossenkopp, KP | 1 |
| Piomelli, D | 1 |
| Sharkey, KA | 2 |
| Cristino, L | 1 |
| Oland, LD | 1 |
| Van Sickle, MD | 1 |
| Starowicz, K | 1 |
| Pittman, QJ | 1 |
| Guglielmotti, V | 1 |
| Davison, JS | 1 |
| Di Marzo, V | 1 |
| Miller, MJ | 1 |
| Reuter, BK | 1 |
| Wallace, JL | 1 |
| Simoneau, II | 1 |
| Hamza, MS | 1 |
| Mata, HP | 1 |
| Siegel, EM | 1 |
| Vanderah, TW | 1 |
| Porreca, F | 1 |
| Makriyannis, A | 1 |
| Malan, TP | 1 |
5 other studies available for am 251 and Vomiting
| Article | Year |
|---|---|
Inhibition of monoacylglycerol lipase attenuates vomiting in Suncus murinus and 2-arachidonoyl glycerol attenuates nausea in rats.
Topics: Animals; Arachidonic Acids; Behavior, Animal; Benzodioxoles; Brain; Endocannabinoids; Enzyme Inhibit | 2012 |
Effects of the FAAH inhibitor, URB597, and anandamide on lithium-induced taste reactivity responses: a measure of nausea in the rat.
Topics: Amidohydrolases; Animals; Arachidonic Acids; Association Learning; Avoidance Learning; Benzamides; C | 2007 |
Arvanil, anandamide and N-arachidonoyl-dopamine (NADA) inhibit emesis through cannabinoid CB1 and vanilloid TRPV1 receptors in the ferret.
Topics: Acrylamides; Animals; Antiemetics; Arachidonic Acids; Area Postrema; Autonomic Pathways; Brain Stem; | 2007 |
A unique therapeutic approach to emesis and itch with a proanthocyanidin-rich genonutrient.
Topics: Animals; Antiemetics; Antipruritics; Cell Line; Croton; Ferrets; Male; Mice; Mice, Inbred C57BL; Mor | 2008 |
The cannabinoid agonist WIN55,212-2 suppresses opioid-induced emesis in ferrets.
Topics: Analgesics, Opioid; Animals; Antiemetics; Benzoxazines; Ferrets; Male; Morphine; Morpholines; Naphth | 2001 |