Page last updated: 2024-10-22

am 251 and Uveitis

am 251 has been researched along with Uveitis in 1 studies

AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.

Uveitis: Inflammation of part or all of the uvea, the middle (vascular) tunic of the eye, and commonly involving the other tunics (sclera and cornea, and the retina). (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"This study aimed to investigate the effects of anandamide or arachidonylethanolamide (AEA), an endogenous cannabinoid receptor agonist, on intraocular inflammation in an endotoxin-induced uveitis (EIU) model in rabbits."7.77A cannabinoid ligand, anandamide, exacerbates endotoxin-induced uveitis in rabbits. ( Altinsoy, A; Bagriacik, EU; Dileköz, E; Ercan, ZS; Ilhan, SÖ; Kul, O; Or, M; Sarioglu, Y; Seven, I; Tunccan, OG, 2011)
"This study aimed to investigate the effects of anandamide or arachidonylethanolamide (AEA), an endogenous cannabinoid receptor agonist, on intraocular inflammation in an endotoxin-induced uveitis (EIU) model in rabbits."3.77A cannabinoid ligand, anandamide, exacerbates endotoxin-induced uveitis in rabbits. ( Altinsoy, A; Bagriacik, EU; Dileköz, E; Ercan, ZS; Ilhan, SÖ; Kul, O; Or, M; Sarioglu, Y; Seven, I; Tunccan, OG, 2011)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Altinsoy, A1
Dileköz, E1
Kul, O1
Ilhan, SÖ1
Tunccan, OG1
Seven, I1
Bagriacik, EU1
Sarioglu, Y1
Or, M1
Ercan, ZS1

Other Studies

1 other study available for am 251 and Uveitis

ArticleYear
A cannabinoid ligand, anandamide, exacerbates endotoxin-induced uveitis in rabbits.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2011, Volume: 27, Issue:6

    Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Disease Models, Animal; Drug Synergism; E

2011