Page last updated: 2024-10-22

am 251 and Pyrexia

am 251 has been researched along with Pyrexia in 5 studies

AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.

Research Excerpts

ExcerptRelevanceReference
"This study aims to explore the contribution of endocannabinoids on the cascade of mediators involved in LPS-induced fever and to verify the participation of prostaglandins and endogenous opioids in fever induced by anandamide (AEA)."3.83Endocannabinoids, through opioids and prostaglandins, contribute to fever induced by key pyrogenic mediators. ( Fraga, D; Parada, CA; Rae, GA; Souza, GEP; Zampronio, AR; Zanoni, CIS, 2016)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duncan, M1
Galic, MA1
Wang, A1
Chambers, AP1
McCafferty, DM1
McKay, DM1
Sharkey, KA1
Pittman, QJ1
Fraga, D2
Zanoni, CIS1
Zampronio, AR1
Parada, CA2
Rae, GA2
Souza, GEP1
Amico, JA1
Miedlar, JA1
Cai, HM1
Vollmer, RR1
Zanoni, CI1
Souza, GE1
TouriƱo, C1
Zimmer, A1
Valverde, O1

Other Studies

5 other studies available for am 251 and Pyrexia

ArticleYear
Cannabinoid 1 receptors are critical for the innate immune response to TLR4 stimulation.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2013, Aug-01, Volume: 305, Issue:3

    Topics: Animals; Body Temperature; Cytokines; Data Interpretation, Statistical; Fever; Hyperalgesia; Immunit

2013
Endocannabinoids, through opioids and prostaglandins, contribute to fever induced by key pyrogenic mediators.
    Brain, behavior, and immunity, 2016, Volume: 51

    Topics: Animals; Arachidonic Acids; beta-Endorphin; Body Temperature; Corticotropin-Releasing Hormone; Cytok

2016
Oxytocin knockout mice: a model for studying stress-related and ingestive behaviours.
    Progress in brain research, 2008, Volume: 170

    Topics: Animals; Body Temperature; Corticosterone; Crosses, Genetic; Environment; Feeding Behavior; Female;

2008
Endogenous cannabinoids induce fever through the activation of CB1 receptors.
    British journal of pharmacology, 2009, Volume: 157, Issue:8

    Topics: Animals; Arachidonic Acids; Body Temperature; Body Temperature Regulation; Cannabinoid Receptor Modu

2009
THC Prevents MDMA Neurotoxicity in Mice.
    PloS one, 2010, Feb-10, Volume: 5, Issue:2

    Topics: Animals; Astrocytes; Body Temperature; Dronabinol; Fever; Hallucinogens; Indoles; Mice; Mice, Inbred

2010