am 251 and Pregnancy
am 251 has been researched along with Pregnancy in 11 studies
AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "In agreement with the neurodevelopmental hypothesis of schizophrenia, prenatal exposure of rats to the antimitotic agent methylazoxymethanol acetate (MAM) at gestational day 17 produced long-lasting behavioral alterations such as social withdrawal and cognitive impairment in the social interaction test and in the novel object recognition test, respectively." | 7.91 | Peripubertal cannabidiol treatment rescues behavioral and neurochemical abnormalities in the MAM model of schizophrenia. ( Babinska, Z; Bari, M; D'Addario, C; Di Bartolomeo, M; Di Marco, R; Di Marzo, V; Drago, F; Drazanova, E; Giurdanella, G; Iannotti, FA; Maccarrone, M; Mechoulam, R; Micale, V; Pekarik, V; Piscitelli, F; Ruda-Kucerova, J; Salomone, S; Starcuk, Z; Stark, T; Sulcova, A; Wotjak, CT, 2019) |
| "In agreement with the neurodevelopmental hypothesis of schizophrenia, prenatal exposure of rats to the antimitotic agent methylazoxymethanol acetate (MAM) at gestational day 17 produced long-lasting behavioral alterations such as social withdrawal and cognitive impairment in the social interaction test and in the novel object recognition test, respectively." | 3.91 | Peripubertal cannabidiol treatment rescues behavioral and neurochemical abnormalities in the MAM model of schizophrenia. ( Babinska, Z; Bari, M; D'Addario, C; Di Bartolomeo, M; Di Marco, R; Di Marzo, V; Drago, F; Drazanova, E; Giurdanella, G; Iannotti, FA; Maccarrone, M; Mechoulam, R; Micale, V; Pekarik, V; Piscitelli, F; Ruda-Kucerova, J; Salomone, S; Starcuk, Z; Stark, T; Sulcova, A; Wotjak, CT, 2019) |
Research
Studies (11)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 6 (54.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Stark, T | 1 |
| Ruda-Kucerova, J | 1 |
| Iannotti, FA | 1 |
| D'Addario, C | 1 |
| Di Marco, R | 1 |
| Pekarik, V | 1 |
| Drazanova, E | 1 |
| Piscitelli, F | 1 |
| Bari, M | 1 |
| Babinska, Z | 1 |
| Giurdanella, G | 1 |
| Di Bartolomeo, M | 1 |
| Salomone, S | 1 |
| Sulcova, A | 1 |
| Maccarrone, M | 1 |
| Wotjak, CT | 1 |
| Starcuk, Z | 1 |
| Drago, F | 1 |
| Mechoulam, R | 1 |
| Di Marzo, V | 2 |
| Micale, V | 1 |
| Kotlar, I | 1 |
| Rangel-López, E | 1 |
| Colonnello, A | 1 |
| Aguilera-Portillo, G | 1 |
| Serratos, IN | 1 |
| Galván-Arzate, S | 1 |
| Pedraza-Chaverri, J | 1 |
| Túnez, I | 1 |
| Wajner, M | 1 |
| Santamaría, A | 1 |
| Tree, KC | 1 |
| Scotto di Perretolo, M | 1 |
| Peyronnet, J | 1 |
| Cayetanot, F | 1 |
| Ramírez-López, MT | 1 |
| Arco, R | 1 |
| Decara, J | 1 |
| Vázquez, M | 1 |
| Noemí Blanco, R | 1 |
| Alén, F | 1 |
| Suárez, J | 1 |
| Gómez de Heras, R | 1 |
| Rodríguez de Fonseca, F | 1 |
| Amico, JA | 1 |
| Miedlar, JA | 1 |
| Cai, HM | 1 |
| Vollmer, RR | 1 |
| Fonseca, BM | 1 |
| Correia-da-Silva, G | 1 |
| Teixeira, NA | 1 |
| Tebano, MT | 1 |
| Martire, A | 1 |
| Chiodi, V | 1 |
| Pepponi, R | 1 |
| Ferrante, A | 1 |
| Domenici, MR | 1 |
| Frank, C | 1 |
| Chen, JF | 1 |
| Ledent, C | 1 |
| Popoli, P | 1 |
| Weems, YS | 1 |
| Lewis, AW | 1 |
| Neuendorff, DA | 1 |
| Randel, RD | 1 |
| Weems, CW | 1 |
| D'Asti, E | 1 |
| Long, H | 2 |
| Tremblay-Mercier, J | 1 |
| Grajzer, M | 1 |
| Cunnane, SC | 1 |
| Walker, CD | 2 |
| Buwembo, A | 1 |
| Paria, BC | 1 |
| Ma, W | 1 |
| Andrenyak, DM | 1 |
| Schmid, PC | 1 |
| Schmid, HH | 1 |
| Moody, DE | 1 |
| Deng, H | 1 |
| Makriyannis, A | 1 |
| Dey, SK | 1 |
Other Studies
11 other studies available for am 251 and Pregnancy
| Article | Year |
|---|---|
Peripubertal cannabidiol treatment rescues behavioral and neurochemical abnormalities in the MAM model of schizophrenia.
Topics: Amides; Animals; Arachidonic Acids; Cannabidiol; Disease Models, Animal; Endocannabinoids; Ethanolam | 2019 |
Anandamide Reduces the Toxic Synergism Exerted by Quinolinic Acid and Glutaric Acid in Rat Brain Neuronal Cells.
Topics: Animals; Arachidonic Acids; Benzamides; Cannabinoid Receptor Agonists; Carbamates; Cell Survival; Ce | 2019 |
In utero cannabinoid exposure alters breathing and the response to hypoxia in newborn mice.
Topics: Animals; Animals, Newborn; Apnea; Benzoxazines; Cannabinoid Receptor Agonists; Cannabinoid Receptor | 2014 |
Exposure to a Highly Caloric Palatable Diet during the Perinatal Period Affects the Expression of the Endogenous Cannabinoid System in the Brain, Liver and Adipose Tissue of Adult Rat Offspring.
Topics: Adipose Tissue; Animals; Animals, Newborn; Brain; Diet, High-Fat; Endocannabinoids; Female; Gene Exp | 2016 |
Oxytocin knockout mice: a model for studying stress-related and ingestive behaviours.
Topics: Animals; Body Temperature; Corticosterone; Crosses, Genetic; Environment; Feeding Behavior; Female; | 2008 |
Anandamide-induced cell death: dual effects in primary rat decidual cell cultures.
Topics: Animals; Apoptosis; Arachidonic Acids; beta-Cyclodextrins; Cannabinoid Receptor Modulators; Cell Dea | 2009 |
Adenosine A2A receptors enable the synaptic effects of cannabinoid CB1 receptors in the rodent striatum.
Topics: Action Potentials; Animals; Benzoxazines; Biophysics; Calcium; Calcium Channel Blockers; Cerebral Co | 2009 |
Endocannabinoid 1 and 2 (CB(1); CB(2)) receptor agonists affect negatively cow luteal function in vitro.
Topics: Adenine; Adenosine; Animals; Arachidonic Acids; Cattle; Corpus Luteum; Dinoprost; Dinoprostone; Fema | 2009 |
Maternal dietary fat determines metabolic profile and the magnitude of endocannabinoid inhibition of the stress response in neonatal rat offspring.
Topics: Adipose Tissue; Adrenocorticotropic Hormone; Analysis of Variance; Animals; Animals, Suckling; Body | 2010 |
Participation of endocannabinoids in rapid suppression of stress responses by glucocorticoids in neonates.
Topics: Animals; Animals, Newborn; Endocannabinoids; Female; Glucocorticoids; Male; Piperidines; Pregnancy; | 2013 |
Effects of cannabinoids on preimplantation mouse embryo development and implantation are mediated by brain-type cannabinoid receptors.
Topics: Animals; Arachidonic Acids; Brain; Cannabinoids; Cytochrome P-450 Enzyme Inhibitors; Dronabinol; Emb | 1998 |