am 251 has been researched along with Peripheral Nerve Diseases in 3 studies
AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.
| Excerpt | Relevance | Reference |
|---|---|---|
| ") suppressed the maintenance of mechanical and cold allodynia in the cisplatin and paclitaxel models." | 7.78 | The maintenance of cisplatin- and paclitaxel-induced mechanical and cold allodynia is suppressed by cannabinoid CB₂ receptor activation and independent of CXCR4 signaling in models of chemotherapy-induced peripheral neuropathy. ( Deng, L; Guindon, J; Hohmann, AG; Makriyannis, A; Thakur, GA; Vemuri, VK; White, FA, 2012) |
| ") suppressed the maintenance of mechanical and cold allodynia in the cisplatin and paclitaxel models." | 3.78 | The maintenance of cisplatin- and paclitaxel-induced mechanical and cold allodynia is suppressed by cannabinoid CB₂ receptor activation and independent of CXCR4 signaling in models of chemotherapy-induced peripheral neuropathy. ( Deng, L; Guindon, J; Hohmann, AG; Makriyannis, A; Thakur, GA; Vemuri, VK; White, FA, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Segat, GC | 1 |
| Manjavachi, MN | 1 |
| Matias, DO | 1 |
| Passos, GF | 1 |
| Freitas, CS | 1 |
| Costa, R | 1 |
| Calixto, JB | 1 |
| Deng, L | 1 |
| Guindon, J | 1 |
| Vemuri, VK | 1 |
| Thakur, GA | 1 |
| White, FA | 1 |
| Makriyannis, A | 1 |
| Hohmann, AG | 1 |
| Liu, C | 1 |
| Walker, JM | 1 |
3 other studies available for am 251 and Peripheral Nerve Diseases
| Article | Year |
|---|---|
Antiallodynic effect of β-caryophyllene on paclitaxel-induced peripheral neuropathy in mice.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phyto | 2017 |
The maintenance of cisplatin- and paclitaxel-induced mechanical and cold allodynia is suppressed by cannabinoid CB₂ receptor activation and independent of CXCR4 signaling in models of chemotherapy-induced peripheral neuropathy.
Topics: Animals; Benzylamines; Chromones; Cisplatin; Cryopyrin-Associated Periodic Syndromes; Cyclams; Disea | 2012 |
Effects of a cannabinoid agonist on spinal nociceptive neurons in a rodent model of neuropathic pain.
Topics: Analgesics; Animals; Behavior, Animal; Benzoxazines; Camphanes; Cannabinoid Receptor Agonists; Canna | 2006 |