am 251 has been researched along with Panic Disorder in 6 studies
AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.
Panic Disorder: A type of anxiety disorder characterized by unexpected panic attacks that last minutes or, rarely, hours. Panic attacks begin with intense apprehension, fear or terror and, often, a feeling of impending doom. Symptoms experienced during a panic attack include dyspnea or sensations of being smothered; dizziness, loss of balance or faintness; choking sensations; palpitations or accelerated heart rate; shakiness; sweating; nausea or other form of abdominal distress; depersonalization or derealization; paresthesias; hot flashes or chills; chest discomfort or pain; fear of dying and fear of not being in control of oneself or going crazy. Agoraphobia may also develop. Similar to other anxiety disorders, it may be inherited as an autosomal dominant trait.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 5 (83.33) | 24.3611 |
2020's | 1 (16.67) | 2.80 |
Authors | Studies |
---|---|
Khan, AU | 1 |
Falconi-Sobrinho, LL | 2 |
Dos Anjos-Garcia, T | 2 |
de Fátima Dos Santos Sampaio, M | 1 |
de Souza Crippa, JA | 1 |
Menescal-de-Oliveira, L | 1 |
Coimbra, NC | 2 |
Viana, TG | 2 |
Bastos, JR | 2 |
Costa, RB | 1 |
Hott, SC | 2 |
Mansur, FS | 1 |
Coimbra, CC | 1 |
Resstel, LB | 2 |
Aguiar, DC | 3 |
Moreira, FA | 4 |
Batista, LA | 1 |
Gobira, PH | 1 |
Almeida-Santos, AF | 1 |
Guimaraes, FS | 1 |
Ullah, F | 1 |
6 other studies available for am 251 and Panic Disorder
Article | Year |
---|---|
Cannabidiol-induced panicolytic-like effects and fear-induced antinociception impairment: the role of the CB
Topics: Animals; Cannabidiol; Fear; Injections, Intraventricular; Male; N-Methylaspartate; Pain Measurement; | 2020 |
Hypothalamic endocannabinoid signalling modulates aversive responses related to panic attacks.
Topics: Animals; Arachidonic Acids; Benzamides; Biphenyl Compounds; Blood Pressure; Cannabinoids; Carbamates | 2019 |
Anti-aversive role of the endocannabinoid system in the periaqueductal gray stimulation model of panic attacks in rats.
Topics: Amidohydrolases; Animals; Anxiety; Arachidonic Acids; Behavior, Animal; Benzamides; Carbamates; Dise | 2015 |
Role of endocannabinoid signalling in the dorsolateral periaqueductal grey in the modulation of distinct panic-like responses.
Topics: Animals; Arachidonic Acids; Benzamides; Carbamates; Disease Models, Animal; Dose-Response Relationsh | 2015 |
Role of the endocannabinoid 2-arachidonoylglycerol in aversive responses mediated by the dorsolateral periaqueductal grey.
Topics: Animals; Arachidonic Acids; Biphenyl Compounds; Cannabinoid Receptor Antagonists; Disease Models, An | 2016 |
CB
Topics: Animals; Arachidonic Acids; Bicuculline; Disease Models, Animal; Endocannabinoids; Escape Reaction; | 2017 |