Page last updated: 2024-10-22

am 251 and Panic Disorder

am 251 has been researched along with Panic Disorder in 6 studies

AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.

Panic Disorder: A type of anxiety disorder characterized by unexpected panic attacks that last minutes or, rarely, hours. Panic attacks begin with intense apprehension, fear or terror and, often, a feeling of impending doom. Symptoms experienced during a panic attack include dyspnea or sensations of being smothered; dizziness, loss of balance or faintness; choking sensations; palpitations or accelerated heart rate; shakiness; sweating; nausea or other form of abdominal distress; depersonalization or derealization; paresthesias; hot flashes or chills; chest discomfort or pain; fear of dying and fear of not being in control of oneself or going crazy. Agoraphobia may also develop. Similar to other anxiety disorders, it may be inherited as an autosomal dominant trait.

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (83.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Khan, AU1
Falconi-Sobrinho, LL2
Dos Anjos-Garcia, T2
de Fátima Dos Santos Sampaio, M1
de Souza Crippa, JA1
Menescal-de-Oliveira, L1
Coimbra, NC2
Viana, TG2
Bastos, JR2
Costa, RB1
Hott, SC2
Mansur, FS1
Coimbra, CC1
Resstel, LB2
Aguiar, DC3
Moreira, FA4
Batista, LA1
Gobira, PH1
Almeida-Santos, AF1
Guimaraes, FS1
Ullah, F1

Other Studies

6 other studies available for am 251 and Panic Disorder

ArticleYear
Cannabidiol-induced panicolytic-like effects and fear-induced antinociception impairment: the role of the CB
    Psychopharmacology, 2020, Volume: 237, Issue:4

    Topics: Animals; Cannabidiol; Fear; Injections, Intraventricular; Male; N-Methylaspartate; Pain Measurement;

2020
Hypothalamic endocannabinoid signalling modulates aversive responses related to panic attacks.
    Neuropharmacology, 2019, Volume: 148

    Topics: Animals; Arachidonic Acids; Benzamides; Biphenyl Compounds; Blood Pressure; Cannabinoids; Carbamates

2019
Anti-aversive role of the endocannabinoid system in the periaqueductal gray stimulation model of panic attacks in rats.
    Psychopharmacology, 2015, Volume: 232, Issue:9

    Topics: Amidohydrolases; Animals; Anxiety; Arachidonic Acids; Behavior, Animal; Benzamides; Carbamates; Dise

2015
Role of endocannabinoid signalling in the dorsolateral periaqueductal grey in the modulation of distinct panic-like responses.
    Journal of psychopharmacology (Oxford, England), 2015, Volume: 29, Issue:3

    Topics: Animals; Arachidonic Acids; Benzamides; Carbamates; Disease Models, Animal; Dose-Response Relationsh

2015
Role of the endocannabinoid 2-arachidonoylglycerol in aversive responses mediated by the dorsolateral periaqueductal grey.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2016, Volume: 26, Issue:1

    Topics: Animals; Arachidonic Acids; Biphenyl Compounds; Cannabinoid Receptor Antagonists; Disease Models, An

2016
CB
    Neuropharmacology, 2017, Volume: 113, Issue:Pt A

    Topics: Animals; Arachidonic Acids; Bicuculline; Disease Models, Animal; Endocannabinoids; Escape Reaction;

2017