am 251 has been researched along with Muscle Contraction in 5 studies
AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lan, R | 1 |
| Liu, Q | 1 |
| Fan, P | 1 |
| Lin, S | 1 |
| Fernando, SR | 1 |
| McCallion, D | 1 |
| Pertwee, R | 1 |
| Makriyannis, A | 1 |
| Makwana, R | 1 |
| Molleman, A | 1 |
| Parsons, ME | 1 |
| Romano, MR | 1 |
| Lograno, MD | 1 |
| Ates, M | 1 |
| Hamza, M | 1 |
| Seidel, K | 1 |
| Kotalla, CE | 1 |
| Ledent, C | 1 |
| Gühring, H | 1 |
| Barun, S | 1 |
| Vural, IM | 1 |
| Dileköz, E | 1 |
| Ercan, ZS | 1 |
| Sarioglu, Y | 1 |
5 other studies available for am 251 and Muscle Contraction
| Article | Year |
|---|---|
Structure-activity relationships of pyrazole derivatives as cannabinoid receptor antagonists.
Topics: Animals; Cannabinoids; Guinea Pigs; Humans; In Vitro Techniques; Intestine, Small; Male; Mice; Muscl | 1999 |
Evidence for both inverse agonism at the cannabinoid CB1 receptor and the lack of an endogenous cannabinoid tone in the rat and guinea-pig isolated ileum myenteric plexus-longitudinal muscle preparation.
Topics: Amidohydrolases; Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Cannabinoids; Dronabin | 2010 |
Signaling cross-talk between cannabinoid and muscarinic systems actives Rho-kinase and increases the contractile responses of the bovine ciliary muscle.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Carbach | 2013 |
Intrathecally applied flurbiprofen produces an endocannabinoid-dependent antinociception in the rat formalin test.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cannabinoid Receptor Modulators; Cyclo | 2003 |
Effects of cannabinoid receptor activation on rabbit bisected vas deferens strips.
Topics: Animals; Arachidonic Acids; Benzoxazines; Calcium Channel Blockers; Cannabinoid Receptor Agonists; D | 2005 |