Page last updated: 2024-10-22

am 251 and Morphine Abuse

am 251 has been researched along with Morphine Abuse in 2 studies

AM 251: an analog of SR141716A; structure given in first source
AM-251 : A carbohydrazide obtained by formal condensation of the carboxy group of 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. An antagonist at the CB1 cannabinoid receptor.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Khaleghzadeh-Ahangar, H1
Khodagholi, F1
Shaerzadeh, F1
Haghparast, A1
Manwell, LA1
Satvat, E1
Lang, ST1
Allen, CP1
Leri, F1
Parker, LA1

Other Studies

2 other studies available for am 251 and Morphine Abuse

ArticleYear
Modulatory role of the intra-accumbal CB1 receptor in protein level of the c-fos and pCREB/CREB ratio in the nucleus accumbens and ventral tegmental area in extinction and morphine seeking in the rats.
    Brain research bulletin, 2018, Volume: 142

    Topics: Animals; Benzoxazines; Cannabinoid Receptor Modulators; Cyclic AMP Response Element-Binding Protein;

2018
FAAH inhibitor, URB-597, promotes extinction and CB(1) antagonist, SR141716, inhibits extinction of conditioned aversion produced by naloxone-precipitated morphine withdrawal, but not extinction of conditioned preference produced by morphine in rats.
    Pharmacology, biochemistry, and behavior, 2009, Volume: 94, Issue:1

    Topics: Amidohydrolases; Animals; Benzamides; Cannabinoid Receptor Modulators; Carbamates; Choice Behavior;

2009